Click here to switch to the map view.

The map label for this gene is sodB [H]

Identifier: 74317033

GI number: 74317033

Start: 1083582

End: 1084166

Strand: Direct

Name: sodB [H]

Synonym: Tbd_1015

Alternate gene names: 74317033

Gene position: 1083582-1084166 (Clockwise)

Preceding gene: 74317032

Following gene: 74317040

Centisome position: 37.24

GC content: 59.83

Gene sequence:

>585_bases
ATGGAACATACCTTGCCCGCACTGCCTTTTGCTATGGACGCGCTCGAGCCGCACATGTCGAAGGAGACCTTCGAATACCA
CTACGCCAAGCACCATCAGGCCTACGTCACGAATCTCAACAACCTGATCAAGGGTGGCGAATTCGAGAGCAAGTCCCTCG
AGGACATCGTCAAGACCGCTCCGGCCGGCGGCATCTACAACAATGCGGCGCAAGTCTGGAACCACACCTTCTTCTGGAAC
TGTCTGACCCCCAACGGTGGCGGTGCCCCGAGCGGCGCGCTCGCTGACGCGATCAACAAGAAGTGGGGTTCGCTCGACGA
ATTCAAGAAGGCCTTCCAGACCAGCGCCGTCGGCAACTTCGGCTCCGGCTGGACCTGGCTCGTCAAGAAGGCCGACGGCT
CGGTCGACATCGTCAACATGGGCGCCGCCGGCACCCCGCTGACCACCGGCGACAAGGCCCTGTTGTGCGTCGACGTGTGG
GAGCACGCCTACTACATCGACTACCGCAACCTGCGTCCCAAGTTCGTCGAGACCTTCCTCAACAACATGGTGAACTGGAA
GTTTGCCGAAGCGAATTTCGCTTAA

Upstream 100 bases:

>100_bases
CGGCAATCAAAACCGGATGCGTGAAAGGGTCTGCAAAGCGCGCCGGACGCACTAGAGTGTTTAGTTGTTGTTTCAGTTTG
TTCAATATCAGGAGAGAGTT

Downstream 100 bases:

>100_bases
GCTGCTTTGCGCGCATCGCGCTTCTGCATAGGCATCAAAAACCGGGACCGAGTGTCCCGGTTTTGTTTGGCAGGCGACGC
CGCGGCCGCAAAATTGGATC

Product: superoxide dismutase, Fe

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MEHTLPALPFAMDALEPHMSKETFEYHYAKHHQAYVTNLNNLIKGGEFESKSLEDIVKTAPAGGIYNNAAQVWNHTFFWN
CLTPNGGGAPSGALADAINKKWGSLDEFKKAFQTSAVGNFGSGWTWLVKKADGSVDIVNMGAAGTPLTTGDKALLCVDVW
EHAYYIDYRNLRPKFVETFLNNMVNWKFAEANFA

Sequences:

>Translated_194_residues
MEHTLPALPFAMDALEPHMSKETFEYHYAKHHQAYVTNLNNLIKGGEFESKSLEDIVKTAPAGGIYNNAAQVWNHTFFWN
CLTPNGGGAPSGALADAINKKWGSLDEFKKAFQTSAVGNFGSGWTWLVKKADGSVDIVNMGAAGTPLTTGDKALLCVDVW
EHAYYIDYRNLRPKFVETFLNNMVNWKFAEANFA
>Mature_194_residues
MEHTLPALPFAMDALEPHMSKETFEYHYAKHHQAYVTNLNNLIKGGEFESKSLEDIVKTAPAGGIYNNAAQVWNHTFFWN
CLTPNGGGAPSGALADAINKKWGSLDEFKKAFQTSAVGNFGSGWTWLVKKADGSVDIVNMGAAGTPLTTGDKALLCVDVW
EHAYYIDYRNLRPKFVETFLNNMVNWKFAEANFA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=198, Percent_Identity=40.4040404040404, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI67782305, Length=198, Percent_Identity=40.4040404040404, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI67782309, Length=189, Percent_Identity=34.9206349206349, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1787946, Length=194, Percent_Identity=62.3711340206186, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI1790342, Length=207, Percent_Identity=40.5797101449275, Blast_Score=143, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17506561, Length=203, Percent_Identity=38.423645320197, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17569479, Length=195, Percent_Identity=38.4615384615385, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321796, Length=209, Percent_Identity=35.8851674641148, Blast_Score=115, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136812, Length=198, Percent_Identity=41.9191919191919, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 21526; Mature: 21526

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHTLPALPFAMDALEPHMSKETFEYHYAKHHQAYVTNLNNLIKGGEFESKSLEDIVKTA
CCCCCCCCHHHHHHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
PAGGIYNNAAQVWNHTFFWNCLTPNGGGAPSGALADAINKKWGSLDEFKKAFQTSAVGNF
CCCCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GSGWTWLVKKADGSVDIVNMGAAGTPLTTGDKALLCVDVWEHAYYIDYRNLRPKFVETFL
CCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHH
NNMVNWKFAEANFA
HHHCCEEECCCCCC
>Mature Secondary Structure
MEHTLPALPFAMDALEPHMSKETFEYHYAKHHQAYVTNLNNLIKGGEFESKSLEDIVKTA
CCCCCCCCHHHHHHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
PAGGIYNNAAQVWNHTFFWNCLTPNGGGAPSGALADAINKKWGSLDEFKKAFQTSAVGNF
CCCCCCCCHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GSGWTWLVKKADGSVDIVNMGAAGTPLTTGDKALLCVDVWEHAYYIDYRNLRPKFVETFL
CCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHH
NNMVNWKFAEANFA
HHHCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181762; 12910271 [H]