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The map label for this gene is trxB [H]

Identifier: 74317019

GI number: 74317019

Start: 1068125

End: 1069162

Strand: Reverse

Name: trxB [H]

Synonym: Tbd_1001

Alternate gene names: 74317019

Gene position: 1069162-1068125 (Counterclockwise)

Preceding gene: 74317034

Following gene: 74317018

Centisome position: 36.74

GC content: 64.35

Gene sequence:

>1038_bases
ATGGAAATGCCGCTCCCGGTTTTGGTTAGAATAAGCCACTGCCCCATCCCACCACTCGGAAGCCAAAGAACACGAGCCAT
GAGCACTCAACACCACAAACTTGTCATTCTCGGTTCCGGCCCCGCCGGCTACTCGGCCGCCGTCTATGCGGCGCGCGCCA
ATCTTTCGCCCGTCGTGATCACCGGCATGCAGCAGGGCGGCCAACTGATGACGACGACCGAGGTCGACAACTGGCCGGCC
GACGTCGACGGCGTGCAGGGCCCGGAACTGATGGACCGTTTCCAGCGCCACGCCGAGCGCTTCCAGACCGAGATCATCTT
CGACCAGATCCACACCGCCAAGCTGAGCGAGAAGCCGTTCACGCTGATCGGCGATTCGGCTACTTACACCTGCGACGCGC
TGATCATCGCAACCGGCGCGTCGGCCATGTACCTCGGCCTGCCGTCCGAACAGGCCTTCATGGGCAAGGGCGTGTCGGGC
TGCGCGACCTGCGACGGCTTTTTCTACAAGGGCCAGGACGTCGCCGTCATCGGCGGCGGCAACTCCGCCGTCGAGGAAGC
GCTCTATCTCGCCAACATTGCGCGCCACGTCACCCTGGTGCACCGCCGCGACACCTTCAAGGCCGAGAAGATCCTGATCA
ACAACCTGATGGACAAGGTCAAGGAGGGCAAGATCACGCTCGCGCTCGACAGCACGCTCGACGAAGTACTGGGCGACAAG
ACCGGCGTGACGGGCATGCGCATCAAGAGCACCAAGGACGGCGCGACCCGCGACATTGCGCTGACCGGCGTCTTCATCGC
CATCGGCCACAAGCCCAATACCGGCATCTTCGAAGGGCAGCTCGAACTGGAAGGCGGCTATATCGTCACCCGCGGCGGCA
ACAAGGGCAACGCGACGGCGACCAGCGTCGAGGGCGTGTTCGCCGCCGGCGACGTGCAGGACCACATCTACCGCCAGGCC
GTCACGAGCGCCGGCACTGGCTGCATGGCGGCACTCGACGCCGAGCGCTATCTCGACGCGCTGGGCAAGACCAAGTGA

Upstream 100 bases:

>100_bases
CGTTGCATGCGTGGCGGCAGCGAAGGGGACGAACGGGGAGCGGGTCGCGCCATGGAAAGGTGACGAGCGAAAGTGTGGCG
GATTATACCGGGGCGGCAGC

Downstream 100 bases:

>100_bases
GATGAAACGGCGTCGCAGCGCGCTCGCGCCAGCCGCGTTCGACGCGCTGGCGCGCGTGCGCCGCGTCCTGCACGAACAGC
CTGGCCGTCCGGAACAGGCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MEMPLPVLVRISHCPIPPLGSQRTRAMSTQHHKLVILGSGPAGYSAAVYAARANLSPVVITGMQQGGQLMTTTEVDNWPA
DVDGVQGPELMDRFQRHAERFQTEIIFDQIHTAKLSEKPFTLIGDSATYTCDALIIATGASAMYLGLPSEQAFMGKGVSG
CATCDGFFYKGQDVAVIGGGNSAVEEALYLANIARHVTLVHRRDTFKAEKILINNLMDKVKEGKITLALDSTLDEVLGDK
TGVTGMRIKSTKDGATRDIALTGVFIAIGHKPNTGIFEGQLELEGGYIVTRGGNKGNATATSVEGVFAAGDVQDHIYRQA
VTSAGTGCMAALDAERYLDALGKTK

Sequences:

>Translated_345_residues
MEMPLPVLVRISHCPIPPLGSQRTRAMSTQHHKLVILGSGPAGYSAAVYAARANLSPVVITGMQQGGQLMTTTEVDNWPA
DVDGVQGPELMDRFQRHAERFQTEIIFDQIHTAKLSEKPFTLIGDSATYTCDALIIATGASAMYLGLPSEQAFMGKGVSG
CATCDGFFYKGQDVAVIGGGNSAVEEALYLANIARHVTLVHRRDTFKAEKILINNLMDKVKEGKITLALDSTLDEVLGDK
TGVTGMRIKSTKDGATRDIALTGVFIAIGHKPNTGIFEGQLELEGGYIVTRGGNKGNATATSVEGVFAAGDVQDHIYRQA
VTSAGTGCMAALDAERYLDALGKTK
>Mature_345_residues
MEMPLPVLVRISHCPIPPLGSQRTRAMSTQHHKLVILGSGPAGYSAAVYAARANLSPVVITGMQQGGQLMTTTEVDNWPA
DVDGVQGPELMDRFQRHAERFQTEIIFDQIHTAKLSEKPFTLIGDSATYTCDALIIATGASAMYLGLPSEQAFMGKGVSG
CATCDGFFYKGQDVAVIGGGNSAVEEALYLANIARHVTLVHRRDTFKAEKILINNLMDKVKEGKITLALDSTLDEVLGDK
TGVTGMRIKSTKDGATRDIALTGVFIAIGHKPNTGIFEGQLELEGGYIVTRGGNKGNATATSVEGVFAAGDVQDHIYRQA
VTSAGTGCMAALDAERYLDALGKTK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=67.398119122257, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI87081763, Length=301, Percent_Identity=33.5548172757475, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=45.2012383900929, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=44.7204968944099, Blast_Score=258, Evalue=7e-70,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 36707; Mature: 36707

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMPLPVLVRISHCPIPPLGSQRTRAMSTQHHKLVILGSGPAGYSAAVYAARANLSPVVI
CCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEE
TGMQQGGQLMTTTEVDNWPADVDGVQGPELMDRFQRHAERFQTEIIFDQIHTAKLSEKPF
EECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
TLIGDSATYTCDALIIATGASAMYLGLPSEQAFMGKGVSGCATCDGFFYKGQDVAVIGGG
EEEECCCCEEEEEEEEEECCCEEEEECCCCHHHHCCCCCCCEECCCEEECCCEEEEEECC
NSAVEEALYLANIARHVTLVHRRDTFKAEKILINNLMDKVKEGKITLALDSTLDEVLGDK
CHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCC
TGVTGMRIKSTKDGATRDIALTGVFIAIGHKPNTGIFEGQLELEGGYIVTRGGNKGNATA
CCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEEEECCEEEECCCCCCCCEE
TSVEGVFAAGDVQDHIYRQAVTSAGTGCMAALDAERYLDALGKTK
EEECCEEEECCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEMPLPVLVRISHCPIPPLGSQRTRAMSTQHHKLVILGSGPAGYSAAVYAARANLSPVVI
CCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCEEEE
TGMQQGGQLMTTTEVDNWPADVDGVQGPELMDRFQRHAERFQTEIIFDQIHTAKLSEKPF
EECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
TLIGDSATYTCDALIIATGASAMYLGLPSEQAFMGKGVSGCATCDGFFYKGQDVAVIGGG
EEEECCCCEEEEEEEEEECCCEEEEECCCCHHHHCCCCCCCEECCCEEECCCEEEEEECC
NSAVEEALYLANIARHVTLVHRRDTFKAEKILINNLMDKVKEGKITLALDSTLDEVLGDK
CHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCC
TGVTGMRIKSTKDGATRDIALTGVFIAIGHKPNTGIFEGQLELEGGYIVTRGGNKGNATA
CCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEEEECCEEEECCCCCCCCEE
TSVEGVFAAGDVQDHIYRQAVTSAGTGCMAALDAERYLDALGKTK
EEECCEEEECCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]