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The map label for this gene is slyD [H]

Identifier: 74316993

GI number: 74316993

Start: 1040336

End: 1040821

Strand: Direct

Name: slyD [H]

Synonym: Tbd_0975

Alternate gene names: 74316993

Gene position: 1040336-1040821 (Clockwise)

Preceding gene: 74316991

Following gene: 74316999

Centisome position: 35.75

GC content: 63.58

Gene sequence:

>486_bases
ATGGTCACCGTGACACGGAACAAACTCGTATACATCACCTATTCCATCCTCGACGCGCGCGGAATGGTCGTCGAGCAGCA
CGATCTGCCGGTCGGCTACGTCCAGGGCGCGCACAGCGGCATCCTTCCCGCAATCGAGACGGCCGTGGCGGGGCGCAAGA
TCGGCGACCGCGTCGAGATCCAGTTGTCGCCCGAGGAGGGGTACGGACTGCGTGACGAGAGCCTGGTCTTCGTCGACGAG
ATCGAGAACGTTCCGCCCGAGTTCCGGCGCACCGGCGCCGAAGTCATGTTCGAAAACGAGTCGGGTGAGACGAAGGTTTT
TTACGTCACCTCGGTCGAAAACGGCAAGGTCACGCTCGATGGCAACCCGTCTCTGGCCGGACAAAGCGTGACCTGCCTCA
TCAACGTCGTCGACGTTCGCGACGCGACGCCCGAGGAAATCCGCAACGGCCGCCCGCTCGACGCCGCGGGCGGAACCGTC
CATTAG

Upstream 100 bases:

>100_bases
GACGTGCGATCAGTCGGCCGGGCTTCGAAGGTATCATAAGCAGCGGCAGCGTCGCCGCCGGGGCGTGCGCCTTTCTTTCG
ACGGTTCAGGATGAGACAGC

Downstream 100 bases:

>100_bases
GCCCGATCCTTTCGGCAGGTCCTGACGCAAGAAAGCCGGGATTTCTCCCGGCTTTCCGTTTCAGCCGCGCGTTTTTACTT
GGCCGGGCAGGCTTTGTCGC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase protein

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MVTVTRNKLVYITYSILDARGMVVEQHDLPVGYVQGAHSGILPAIETAVAGRKIGDRVEIQLSPEEGYGLRDESLVFVDE
IENVPPEFRRTGAEVMFENESGETKVFYVTSVENGKVTLDGNPSLAGQSVTCLINVVDVRDATPEEIRNGRPLDAAGGTV
H

Sequences:

>Translated_161_residues
MVTVTRNKLVYITYSILDARGMVVEQHDLPVGYVQGAHSGILPAIETAVAGRKIGDRVEIQLSPEEGYGLRDESLVFVDE
IENVPPEFRRTGAEVMFENESGETKVFYVTSVENGKVTLDGNPSLAGQSVTCLINVVDVRDATPEEIRNGRPLDAAGGTV
H
>Mature_161_residues
MVTVTRNKLVYITYSILDARGMVVEQHDLPVGYVQGAHSGILPAIETAVAGRKIGDRVEIQLSPEEGYGLRDESLVFVDE
IENVPPEFRRTGAEVMFENESGETKVFYVTSVENGKVTLDGNPSLAGQSVTCLINVVDVRDATPEEIRNGRPLDAAGGTV
H

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=154, Percent_Identity=29.2207792207792, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17472; Mature: 17472

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVTRNKLVYITYSILDARGMVVEQHDLPVGYVQGAHSGILPAIETAVAGRKIGDRVEI
CEEEECCEEEEEEEEEECCCCEEEEECCCCEEEECCCCCCCCHHHHHHHCCCCCCCEEEE
QLSPEEGYGLRDESLVFVDEIENVPPEFRRTGAEVMFENESGETKVFYVTSVENGKVTLD
EECCCCCCCCCCCCEEEEECCCCCCHHHHCCCCEEEEECCCCCEEEEEEEEECCCEEEEC
GNPSLAGQSVTCLINVVDVRDATPEEIRNGRPLDAAGGTVH
CCCCCCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVTVTRNKLVYITYSILDARGMVVEQHDLPVGYVQGAHSGILPAIETAVAGRKIGDRVEI
CEEEECCEEEEEEEEEECCCCEEEEECCCCEEEECCCCCCCCHHHHHHHCCCCCCCEEEE
QLSPEEGYGLRDESLVFVDEIENVPPEFRRTGAEVMFENESGETKVFYVTSVENGKVTLD
EECCCCCCCCCCCCEEEEECCCCCCHHHHCCCCEEEEECCCCCEEEEEEEEECCCEEEEC
GNPSLAGQSVTCLINVVDVRDATPEEIRNGRPLDAAGGTVH
CCCCCCCCEEEEEEEEEECCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]