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The map label for this gene is pheA [H]

Identifier: 74316969

GI number: 74316969

Start: 1013368

End: 1014465

Strand: Direct

Name: pheA [H]

Synonym: Tbd_0951

Alternate gene names: 74316969

Gene position: 1013368-1014465 (Clockwise)

Preceding gene: 74316968

Following gene: 74316970

Centisome position: 34.83

GC content: 69.22

Gene sequence:

>1098_bases
ATGAAGGACCAGGCAGGGACTAGGCCCGACGTGTCGGCGGAACTCGGTGCGCTGCGCGCGCGTATTGACAGCATCGACGA
CACGCTCCTTGCGCTGATTTCGGAGCGCGCCGCGCTCGCGCAGCAGGTCGGGCACGCGAAGCAGGGTGAGCGCATCTATC
GGCCCGAGCGCGAAGCGCAGATCGTACGCAGGCTGCGTGAGTCGAATCCCGGCCCGCTGTCGGGCGAGACCGTCGAGCGC
CTGATCCGCGAAATCATGTCGGCCTGCCGCGCGGTCGAGGAAGTGACGCGGGTTGCCTATCTCGGCCCGGCCGGAACGTT
CAGCGAGCAGGCCGTGCACAAGCAGTTCGGCCATGAAGTCGACGCGCTCGCCGAGGCCGACATCGACGCGTGCTTCCATG
CCGTCGAGACCGGCCGCGCCGATTTTGCCGTGGTGCCGGTCGAGAACTCGACCGACGGCGCGGTCGGGCGCACGCTCGAC
CTCGTCGTGGCAAGCCCGCTCAGCATCTGCGGCGAAGTCATGCTGCCGATCCATCAGACCTTGATGCGCAAACACGGCGA
TCTCGACGGCATCCGCCGCGTCTACGGTCACGCGCAATCGCTCGCCCAGTGCCAGCACTGGCTGAGCCGCCACCTGCCCG
ACGCCGAGCGCGTCAGCGTCGTCAGCAACAGCGAGGGCGCGCGCCGCGCCGCGGCAGAGCCGGTAGCGGCGACGCTCGGC
AGCGAAGCGGCCGCTGCGCTTTACGGACTTTCCGTGGTCGCCGCGCGGGTCGAGGACGAGGCGAGCAACACGACGCGCTT
TCTGGTTCTCGGCGCGCACGACGCGGCACCGTCGGGGCGCGACAAGACCTCGCTCGTGATGGGCGCGAAGAACCAGCCGG
GCGCCGTGGTCAAGCTGCTGCAGCCGCTCGCCGACGCGGGCGTGTCGATGAGCAAGTTCGAGTCGCGACCGGCCCGCTCG
GGCACCTGGGAATACCTGTTCTTCGTCGTCTGCGAAGGTCACCGCAAGGACGCACGGCTCGCCGCGGCGCTCGCCGAAAT
CGATTCGCGGGCGGCCTTCCTCAAGATCCTCGGCTCCTACCCTGCGGCGTCGGCATGA

Upstream 100 bases:

>100_bases
TGGCCTACACGCTCGTCGACGTCGACAGCGCGGTGGCGGGATCGGTCATCGCGCAGCTCAACGCGATCGGCGGCGTGCTC
GGCGTGCGCTATCTGCCCGC

Downstream 100 bases:

>100_bases
GCGGCTGCGATTCGATCTGCGCTGCAACCGCGCCGCCCCACGTGCGCGCGATCGCTCCGTATCAGCCCGGCAAGCCGATT
TCCGAGCTTGCACGCGAACT

Product: chorismate mutase / prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKDQAGTRPDVSAELGALRARIDSIDDTLLALISERAALAQQVGHAKQGERIYRPEREAQIVRRLRESNPGPLSGETVER
LIREIMSACRAVEEVTRVAYLGPAGTFSEQAVHKQFGHEVDALAEADIDACFHAVETGRADFAVVPVENSTDGAVGRTLD
LVVASPLSICGEVMLPIHQTLMRKHGDLDGIRRVYGHAQSLAQCQHWLSRHLPDAERVSVVSNSEGARRAAAEPVAATLG
SEAAAALYGLSVVAARVEDEASNTTRFLVLGAHDAAPSGRDKTSLVMGAKNQPGAVVKLLQPLADAGVSMSKFESRPARS
GTWEYLFFVVCEGHRKDARLAAALAEIDSRAAFLKILGSYPAASA

Sequences:

>Translated_365_residues
MKDQAGTRPDVSAELGALRARIDSIDDTLLALISERAALAQQVGHAKQGERIYRPEREAQIVRRLRESNPGPLSGETVER
LIREIMSACRAVEEVTRVAYLGPAGTFSEQAVHKQFGHEVDALAEADIDACFHAVETGRADFAVVPVENSTDGAVGRTLD
LVVASPLSICGEVMLPIHQTLMRKHGDLDGIRRVYGHAQSLAQCQHWLSRHLPDAERVSVVSNSEGARRAAAEPVAATLG
SEAAAALYGLSVVAARVEDEASNTTRFLVLGAHDAAPSGRDKTSLVMGAKNQPGAVVKLLQPLADAGVSMSKFESRPARS
GTWEYLFFVVCEGHRKDARLAAALAEIDSRAAFLKILGSYPAASA
>Mature_365_residues
MKDQAGTRPDVSAELGALRARIDSIDDTLLALISERAALAQQVGHAKQGERIYRPEREAQIVRRLRESNPGPLSGETVER
LIREIMSACRAVEEVTRVAYLGPAGTFSEQAVHKQFGHEVDALAEADIDACFHAVETGRADFAVVPVENSTDGAVGRTLD
LVVASPLSICGEVMLPIHQTLMRKHGDLDGIRRVYGHAQSLAQCQHWLSRHLPDAERVSVVSNSEGARRAAAEPVAATLG
SEAAAALYGLSVVAARVEDEASNTTRFLVLGAHDAAPSGRDKTSLVMGAKNQPGAVVKLLQPLADAGVSMSKFESRPARS
GTWEYLFFVVCEGHRKDARLAAALAEIDSRAAFLKILGSYPAASA

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=377, Percent_Identity=33.42175066313, Blast_Score=179, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324013, Length=320, Percent_Identity=25.9375, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39031; Mature: 39031

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDQAGTRPDVSAELGALRARIDSIDDTLLALISERAALAQQVGHAKQGERIYRPEREAQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHH
IVRRLRESNPGPLSGETVERLIREIMSACRAVEEVTRVAYLGPAGTFSEQAVHKQFGHEV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHH
DALAEADIDACFHAVETGRADFAVVPVENSTDGAVGRTLDLVVASPLSICGEVMLPIHQT
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHH
LMRKHGDLDGIRRVYGHAQSLAQCQHWLSRHLPDAERVSVVSNSEGARRAAAEPVAATLG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHCCHHHHHHC
SEAAAALYGLSVVAARVEDEASNTTRFLVLGAHDAAPSGRDKTSLVMGAKNQPGAVVKLL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHH
QPLADAGVSMSKFESRPARSGTWEYLFFVVCEGHRKDARLAAALAEIDSRAAFLKILGSY
HHHHHCCCCHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PAASA
CCCCC
>Mature Secondary Structure
MKDQAGTRPDVSAELGALRARIDSIDDTLLALISERAALAQQVGHAKQGERIYRPEREAQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHH
IVRRLRESNPGPLSGETVERLIREIMSACRAVEEVTRVAYLGPAGTFSEQAVHKQFGHEV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHH
DALAEADIDACFHAVETGRADFAVVPVENSTDGAVGRTLDLVVASPLSICGEVMLPIHQT
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHH
LMRKHGDLDGIRRVYGHAQSLAQCQHWLSRHLPDAERVSVVSNSEGARRAAAEPVAATLG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHCCHHHHHHC
SEAAAALYGLSVVAARVEDEASNTTRFLVLGAHDAAPSGRDKTSLVMGAKNQPGAVVKLL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHH
QPLADAGVSMSKFESRPARSGTWEYLFFVVCEGHRKDARLAAALAEIDSRAAFLKILGSY
HHHHHCCCCHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PAASA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]