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The map label for this gene is comL [H]

Identifier: 74316827

GI number: 74316827

Start: 850817

End: 851662

Strand: Reverse

Name: comL [H]

Synonym: Tbd_0809

Alternate gene names: 74316827

Gene position: 851662-850817 (Counterclockwise)

Preceding gene: 74316830

Following gene: 74316822

Centisome position: 29.27

GC content: 62.88

Gene sequence:

>846_bases
ATGCTTGAGCAATGTTCTTCCCGTATTAACGCGTTCGTCCGGTCACGCGGCCTCCCCGGGGCCGGTCGCGCCGCATTGCT
GGCAGCGGCGCTCGCGCTCGGCGGTTGCGGTCTGCTGCCCGAGGTCAAGGACGAGACCACGGGCTGGTCGGCGCAGAAGC
TCTATGCCGAGGCCAAGGACAACCTCAACGAGGGCAACTACGAACGCGCGGTCAAGCTCTTCGAAACGCTCGAATCGCGC
TACCCCTTCGGCCGTTACGCGCAGCAGGCGCAACTCGAAGTCGCCTACGCCTATTACAAGGACAACGAGCCGATCTCGGC
GGTCGCCGCATGCGACCGTTTCATCAAGCTCCACCCCAACCACCCTAACGTCGATTACGCGTACTATCTGAAGGGGCTGG
CGAATTTTAACGACGACCTCGGTCTGCTGGGCAACCTCGTCGACCAGGACATGAGCGAGCGCGACCCGCGCGCCGCACGG
GACGCCTTCCTCGCGTTCAAGGAACTGGCCACGCGTTTCCCGCAGAGCATTTACGCGGCCGACGCGACCGCGCGGATGAA
ATACCTCGTCAACGCGCTCGCCAACAACGAGGTCCACGTTGCCAAGTACTATCTGAAGCGCAAGGCCTACGTCGCGGCCG
CGAACCGTGCCAAGGAAGTGCTGAAAACTTATCCCGAAGCGCCCGCGCTCGAAGAGGCGCTGGCGATCATGGCCTTGTCC
TACGACCGCCTCAAGCTGCCCGAATTGCGCGACGACGCGCGCCGGGTGCTGACGCTCAACTTCCCCAACAGCAAGTATCT
CCAGGGCGTGAGCATCAAGGAAAAGGCCTGGTACCGCTTCTGGTGA

Upstream 100 bases:

>100_bases
CAGACGCAGCCCGCCCTGCGCGTCGGGGATGACGAGCTCGCGGACGTCGCCCCCGCTATTTCCCTTATAATCGTCCATCA
AATTTTCTGTTTCTTTTCCC

Downstream 100 bases:

>100_bases
AGCCAACCCGCGGCTGAAACCGCGGGTATTCCGAATTAGCGACGCTCACACCGCCGCTTCGCCCGATTCCCCGGTGCGGA
TGCGCACCACCTGCTCGACC

Product: putative competence lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MLEQCSSRINAFVRSRGLPGAGRAALLAAALALGGCGLLPEVKDETTGWSAQKLYAEAKDNLNEGNYERAVKLFETLESR
YPFGRYAQQAQLEVAYAYYKDNEPISAVAACDRFIKLHPNHPNVDYAYYLKGLANFNDDLGLLGNLVDQDMSERDPRAAR
DAFLAFKELATRFPQSIYAADATARMKYLVNALANNEVHVAKYYLKRKAYVAAANRAKEVLKTYPEAPALEEALAIMALS
YDRLKLPELRDDARRVLTLNFPNSKYLQGVSIKEKAWYRFW

Sequences:

>Translated_281_residues
MLEQCSSRINAFVRSRGLPGAGRAALLAAALALGGCGLLPEVKDETTGWSAQKLYAEAKDNLNEGNYERAVKLFETLESR
YPFGRYAQQAQLEVAYAYYKDNEPISAVAACDRFIKLHPNHPNVDYAYYLKGLANFNDDLGLLGNLVDQDMSERDPRAAR
DAFLAFKELATRFPQSIYAADATARMKYLVNALANNEVHVAKYYLKRKAYVAAANRAKEVLKTYPEAPALEEALAIMALS
YDRLKLPELRDDARRVLTLNFPNSKYLQGVSIKEKAWYRFW
>Mature_281_residues
MLEQCSSRINAFVRSRGLPGAGRAALLAAALALGGCGLLPEVKDETTGWSAQKLYAEAKDNLNEGNYERAVKLFETLESR
YPFGRYAQQAQLEVAYAYYKDNEPISAVAACDRFIKLHPNHPNVDYAYYLKGLANFNDDLGLLGNLVDQDMSERDPRAAR
DAFLAFKELATRFPQSIYAADATARMKYLVNALANNEVHVAKYYLKRKAYVAAANRAKEVLKTYPEAPALEEALAIMALS
YDRLKLPELRDDARRVLTLNFPNSKYLQGVSIKEKAWYRFW

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=242, Percent_Identity=39.6694214876033, Blast_Score=175, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31654; Mature: 31654

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQCSSRINAFVRSRGLPGAGRAALLAAALALGGCGLLPEVKDETTGWSAQKLYAEAKD
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHC
NLNEGNYERAVKLFETLESRYPFGRYAQQAQLEVAYAYYKDNEPISAVAACDRFIKLHPN
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHEECCC
HPNVDYAYYLKGLANFNDDLGLLGNLVDQDMSERDPRAARDAFLAFKELATRFPQSIYAA
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
DATARMKYLVNALANNEVHVAKYYLKRKAYVAAANRAKEVLKTYPEAPALEEALAIMALS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YDRLKLPELRDDARRVLTLNFPNSKYLQGVSIKEKAWYRFW
HCCCCCCCHHCCCCEEEEEECCCCHHCCCCCCHHCHHCCCC
>Mature Secondary Structure
MLEQCSSRINAFVRSRGLPGAGRAALLAAALALGGCGLLPEVKDETTGWSAQKLYAEAKD
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHC
NLNEGNYERAVKLFETLESRYPFGRYAQQAQLEVAYAYYKDNEPISAVAACDRFIKLHPN
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHEECCC
HPNVDYAYYLKGLANFNDDLGLLGNLVDQDMSERDPRAARDAFLAFKELATRFPQSIYAA
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
DATARMKYLVNALANNEVHVAKYYLKRKAYVAAANRAKEVLKTYPEAPALEEALAIMALS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
YDRLKLPELRDDARRVLTLNFPNSKYLQGVSIKEKAWYRFW
HCCCCCCCHHCCCCEEEEEECCCCHHCCCCCCHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]