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The map label for this gene is sucC

Identifier: 74316823

GI number: 74316823

Start: 846766

End: 847926

Strand: Direct

Name: sucC

Synonym: Tbd_0805

Alternate gene names: 74316823

Gene position: 846766-847926 (Clockwise)

Preceding gene: 74316820

Following gene: 74316824

Centisome position: 29.1

GC content: 67.7

Gene sequence:

>1161_bases
ATGAACCTGCACGAATACCAGGCCAAACAAGTCTTGCGGTCGAGCAACCTTAACACGCCGCGCGGCATCGCTGCGACGAG
CGCCGACGCCGCGGCCGACGCCGCCCGCGAACTGGGCGGCGAGGCCTGGGTCGTGAAGGCCCAGATCCACGCCGGCGGGC
GCGGCAAGGCCGGCGGCGTCAAGGTCGTGACGAGCATCGACGCGGTGCGCAGCGTCGCCGCCGCGTTGCTCGGCAAGCCG
CTCGTCACCGTGCAGAACGCGCCCGACGGCCAGCCGGTCCATACCGTGCTGGTCGAGGAAACGCTGCCGATCGCACGCGA
ACTGTATCTTTCGCTGCTGGTCGACCGTGCCTCCGAGCGCGTCGCGGTCGTCGCGTCGGCCGCGGGCGGCATGGACATCG
AGCAGGTCGCCCATGCCACACCCGAGAAAGTTCTGACCGAGATCTGCGATCCGCTGCTCGGCGTGCAGGATTTCCAGTGC
CGCGCGCTCGCTTTCGCGCTCGGGCTCGGCGGCGACGCCTACAAGGATTTCTGCCGCCTGCTGCCGCAGCTCTACCGTGT
CTTCGTCGCCAATGATCTGAGCCTGCTCGAGATCAATCCGCTCGTCGTCACCACCGACAACCGCGTTCTGCCGCTCGACT
GCAAGATGAGCGTCGACGACAACGCGCTCTACCGCAGGAAGGCGCTCGCCGACCTGCGCGACGACAGCCAGATCGACGCC
AAGGAAGCGGCCGCCAACGCGGCCAACGTCAACTACGTCGCGCTCGCCGGCAACATCGGCTGCATGGTCAACGGTGCCGG
TCTCGCGATGGCGACGATGGACCTGATCCAGCTCGAAGGCGGCGCGCCGGCCAACTTTCTCGACGTCGGCGGCGGAGCGA
CGCCCGAGACCGTCGCGCAGGGCTTCAAGATCATCCTGCTCGACCCCAACGTGAAGGCCGTGCTGATCAACATCTTCGGC
GGCATCGTGCGCTGCGACGTGATCGCCGAGGGCATCATCCAGGCGGTCAGGGAAGTCGGCGTCGAGGTTCCGGTCATCGT
GCGCCTCGAGGGCACGAATGCCGAACTCGGCCGCACCCTGCTGGCCGAATCGGGCCTCGCGATCGTCGCGGCCGAGAGCC
TGACCCAGGCCGCGAAATTCGCCGTGGAGAAAGCGGCATGA

Upstream 100 bases:

>100_bases
GCCGACAGCGCCGCGATGCGCGTCACGACGCGGATCACGGCTTCCGTCGCGGGGACCTTTGCTTCAGAATGCGCGTTTTG
GGGAGTTTCCATCAACAGCG

Downstream 100 bases:

>100_bases
GCATTCTGGTCGACAAGGACACCAAGGTCATCTGCCAGGGCTTCACGGGCAAGCAGGGCAGCTTCCATTCCGAGCAGGCG
ATCGCCTACGGCACCCGCAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNLHEYQAKQVLRSSNLNTPRGIAATSADAAADAARELGGEAWVVKAQIHAGGRGKAGGVKVVTSIDAVRSVAAALLGKP
LVTVQNAPDGQPVHTVLVEETLPIARELYLSLLVDRASERVAVVASAAGGMDIEQVAHATPEKVLTEICDPLLGVQDFQC
RALAFALGLGGDAYKDFCRLLPQLYRVFVANDLSLLEINPLVVTTDNRVLPLDCKMSVDDNALYRRKALADLRDDSQIDA
KEAAANAANVNYVALAGNIGCMVNGAGLAMATMDLIQLEGGAPANFLDVGGGATPETVAQGFKIILLDPNVKAVLINIFG
GIVRCDVIAEGIIQAVREVGVEVPVIVRLEGTNAELGRTLLAESGLAIVAAESLTQAAKFAVEKAA

Sequences:

>Translated_386_residues
MNLHEYQAKQVLRSSNLNTPRGIAATSADAAADAARELGGEAWVVKAQIHAGGRGKAGGVKVVTSIDAVRSVAAALLGKP
LVTVQNAPDGQPVHTVLVEETLPIARELYLSLLVDRASERVAVVASAAGGMDIEQVAHATPEKVLTEICDPLLGVQDFQC
RALAFALGLGGDAYKDFCRLLPQLYRVFVANDLSLLEINPLVVTTDNRVLPLDCKMSVDDNALYRRKALADLRDDSQIDA
KEAAANAANVNYVALAGNIGCMVNGAGLAMATMDLIQLEGGAPANFLDVGGGATPETVAQGFKIILLDPNVKAVLINIFG
GIVRCDVIAEGIIQAVREVGVEVPVIVRLEGTNAELGRTLLAESGLAIVAAESLTQAAKFAVEKAA
>Mature_386_residues
MNLHEYQAKQVLRSSNLNTPRGIAATSADAAADAARELGGEAWVVKAQIHAGGRGKAGGVKVVTSIDAVRSVAAALLGKP
LVTVQNAPDGQPVHTVLVEETLPIARELYLSLLVDRASERVAVVASAAGGMDIEQVAHATPEKVLTEICDPLLGVQDFQC
RALAFALGLGGDAYKDFCRLLPQLYRVFVANDLSLLEINPLVVTTDNRVLPLDCKMSVDDNALYRRKALADLRDDSQIDA
KEAAANAANVNYVALAGNIGCMVNGAGLAMATMDLIQLEGGAPANFLDVGGGATPETVAQGFKIILLDPNVKAVLINIFG
GIVRCDVIAEGIIQAVREVGVEVPVIVRLEGTNAELGRTLLAESGLAIVAAESLTQAAKFAVEKAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=42.5641025641026, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=41.5343915343915, Blast_Score=292, Evalue=3e-79,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=41.7127071823204, Blast_Score=281, Evalue=7e-76,
Organism=Escherichia coli, GI1786948, Length=382, Percent_Identity=56.8062827225131, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.1876606683805, Blast_Score=319, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=43.4782608695652, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=41.7302798982188, Blast_Score=320, Evalue=3e-88,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=44.1326530612245, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=44.1326530612245, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=44.0203562340967, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=44.0203562340967, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=42.3076923076923, Blast_Score=291, Evalue=6e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_THIDA (Q3SKM1)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314563.1
- HSSP:   P53590
- ProteinModelPortal:   Q3SKM1
- SMR:   Q3SKM1
- STRING:   Q3SKM1
- GeneID:   3673502
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0805
- NMPDR:   fig|292415.3.peg.112
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- PhylomeDB:   Q3SKM1
- ProtClustDB:   PRK00696
- BioCyc:   TDEN292415:TBD_0805-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 40316; Mature: 40316

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQVLRSSNLNTPRGIAATSADAAADAARELGGEAWVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVVTSIDAVRSVAAALLGKPLVTVQNAPDGQPVHTVLVEETLPIARELYLSLLVDRASER
EEEHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCC
VAVVASAAGGMDIEQVAHATPEKVLTEICDPLLGVQDFQCRALAFALGLGGDAYKDFCRL
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHH
LPQLYRVFVANDLSLLEINPLVVTTDNRVLPLDCKMSVDDNALYRRKALADLRDDSQIDA
HHHHHHHHHHCCCEEEEECCEEEECCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCH
KEAAANAANVNYVALAGNIGCMVNGAGLAMATMDLIQLEGGAPANFLDVGGGATPETVAQ
HHHHCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCCHHHHHC
GFKIILLDPNVKAVLINIFGGIVRCDVIAEGIIQAVREVGVEVPVIVRLEGTNAELGRTL
CCEEEEECCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAESGLAIVAAESLTQAAKFAVEKAA
HHCCCEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKQVLRSSNLNTPRGIAATSADAAADAARELGGEAWVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVVTSIDAVRSVAAALLGKPLVTVQNAPDGQPVHTVLVEETLPIARELYLSLLVDRASER
EEEHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCC
VAVVASAAGGMDIEQVAHATPEKVLTEICDPLLGVQDFQCRALAFALGLGGDAYKDFCRL
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHH
LPQLYRVFVANDLSLLEINPLVVTTDNRVLPLDCKMSVDDNALYRRKALADLRDDSQIDA
HHHHHHHHHHCCCEEEEECCEEEECCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCH
KEAAANAANVNYVALAGNIGCMVNGAGLAMATMDLIQLEGGAPANFLDVGGGATPETVAQ
HHHHCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCCHHHHHC
GFKIILLDPNVKAVLINIFGGIVRCDVIAEGIIQAVREVGVEVPVIVRLEGTNAELGRTL
CCEEEEECCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAESGLAIVAAESLTQAAKFAVEKAA
HHCCCEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA