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The map label for this gene is fecA [H]

Identifier: 74316740

GI number: 74316740

Start: 763663

End: 765690

Strand: Reverse

Name: fecA [H]

Synonym: Tbd_0722

Alternate gene names: 74316740

Gene position: 765690-763663 (Counterclockwise)

Preceding gene: 74316741

Following gene: 74316739

Centisome position: 26.31

GC content: 66.96

Gene sequence:

>2028_bases
ATGAAGAAGAAGCTGTTGGCTGTACTGATTCCCCTGGCGTTTTCCGCGCACGCGCAGGAGACCGAGCAACTCGAGGCGGT
GAGCGTGAGCGCCGACTGGCTCGGCGCCGCGACGCCGGAAGCGGCGAAGAAGCACCCCGGTGCACGCACCGTCGTCACCG
AGCAGGAACTCGCCGAATCGGGCGCGCGCACCGTCGAAGACGCCTTGCGCACGGTGCCCGGCGTGCGCGTCCTCGACGAA
AGCGGGACCGGCATCCTGCCCAACATCGGCGTGCGCGGCCTCAGCCCGCTGCGCAGCGAACAGGTGCTGGTGCTCGTCGA
CGGCATGCCGATCACGCTCGCGCCCTACGGCCAGACCGGTTTGTCGCTGTTTCCGCTGACGCTCAATGCGGTCGAGGCGA
TCGACGTGGCGCGCGGCGGCGTCGCGGTCCACTACGGCCCGAACAACGTCGGCGGCGTGATCAATTTCGTGACCAAGCGC
ATCCCGCGCAAACCCGCTTTCACTGCGAAGGAGACGCTGTCGATCGCGAGCAGCGGCAATCTGCTCAGCGACACCTACCT
GCGCGCGGGCGGCTTCGTCAGCGAGCGTCTGGGCCTGCAGGCCCAGGCCAATCTCATCGAAGGCGAAGCCGAGCGCGACC
ATTCGAGCACCTCCGTGCAGAACCTCATGCTCGACGCCGACTGGTTCCTGACCGACAGCGCCAACCTCCGCGCCGGCCTG
CAGTACTACAAGACCGAGAACGACATGCCCGGCGCGCTGACGCCGGCCTCGTACGAAGCCGACCGCGAGCAGTCGACCCG
CCCGCTCGACCGCTTCGACGGCGACACGCTGCGCGGCCACGTCACCTACAGCCAGGCTTTCGCCAACGGCGCGGAATTGA
GCTGGGCGAATTTCGCCCACCGCAGCAACCGGCAGTTCTTCTTCGGCAACTCGAGCAACGCCGACACGCCGTCGACCAAC
GAGATGTCGTCGCCGCGCGAATTCTGGGTCTACGGCAGCGAGCCGCGGCTGACCTTCGACATCGACGCGGGCGTCAAGCA
GAAGATCTCGCTCGGCGCGCGCTACCTGCGCGAGGAGGTCGACTACGTCGTCGACTCGCGCACGCTGGCGACCAATGCCT
ACGCGGTCACGCGCGACTGGCGCTTCGAGAACGACGCCGTCGCCGCCTACCTGAGCGACACCTTCTTCCTGCTCGACGAC
AGGCTCAAGGTCACGCCCGGCGTCCGCCACGAAACGGTCGACCTCTATTACCGCAATAACCTGACCGGCGCGGAAACGCG
TGACACGACCAAGGACTGGCTGCCCGGCATCGACATCGGCTATCAGGCGAGCGACGCGGTCTTCCTGTTCGCGAACTATC
ACAAGTCGCTGCGGCCGGTGCAGTTCACGCAGATCACCTTCGGCGGCGACCTCGACGCCGAGCGCGCGGAAAACTACGAA
GCCGGCATCCGCGTCGCGCCGACCGCGAACGTCGATACGAGCCTGACCGCCTTCCGCTTCGACTTCGACAACAAGCTCGA
ATTCGTCAGCCAGGCCGTCGGCTTCCGCAACCTCGGCGAGGCGCGCCATCAGGGCGTCGAGGCCGAAGTCGCGTGGCGCC
CGGCCGCGGTGCGCGGGCTCGAACTCAAGACCGCCTACACCTACGTCGACACCGAGCAACGCTCGGGCCAGTTCGAGGGC
AACGAACTGCCGCTCGCCCCGCACCACCAGCTCAACCTGCAGGGCAACTACCGCAGCGGCGACTGGAACTGGAACCTGAA
CGGCCTCTACCAGAGCGCGTCCTTCTCCGACGGCGCGAACACGGTCGACGAGAACGCGACCGGCTCGGTCGGACGCATCC
CGGCCTATTCGGTATGGAACGCGCAGGTCACGCGCGACTTCCGCTGGAACGGCACGAAGATGAAGGCCGCGCTCGCGCTC
AACAACCTGTTCGATCGCGACTATTACTTCCGCGGCGTCGACTTCAGCCAGGGCCGCATGCCGGCGCCGGGCCGCGCCGC
CTTGCTCACGCTACAGATGGACATGTGA

Upstream 100 bases:

>100_bases
CTTCGCGGCCGCCGGGCCCGCCCACCCTATCGAGTAGAACCGCTACCACCCAGCCAGCCTTACAGCCAGCCAGAAATCCT
TAACCGTATCTGGAGGCTGC

Downstream 100 bases:

>100_bases
GGAGGGCGACCATGCGAGAGCTCATCCTGCTGGCCCACGTGCCGACCGATTCGGTCAACGACGGCTTCATTCCGGCAGCG
CAGCGGCGCGGCCTGTCGGT

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Iron(III) dicitrate transport protein fecA [H]

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MKKKLLAVLIPLAFSAHAQETEQLEAVSVSADWLGAATPEAAKKHPGARTVVTEQELAESGARTVEDALRTVPGVRVLDE
SGTGILPNIGVRGLSPLRSEQVLVLVDGMPITLAPYGQTGLSLFPLTLNAVEAIDVARGGVAVHYGPNNVGGVINFVTKR
IPRKPAFTAKETLSIASSGNLLSDTYLRAGGFVSERLGLQAQANLIEGEAERDHSSTSVQNLMLDADWFLTDSANLRAGL
QYYKTENDMPGALTPASYEADREQSTRPLDRFDGDTLRGHVTYSQAFANGAELSWANFAHRSNRQFFFGNSSNADTPSTN
EMSSPREFWVYGSEPRLTFDIDAGVKQKISLGARYLREEVDYVVDSRTLATNAYAVTRDWRFENDAVAAYLSDTFFLLDD
RLKVTPGVRHETVDLYYRNNLTGAETRDTTKDWLPGIDIGYQASDAVFLFANYHKSLRPVQFTQITFGGDLDAERAENYE
AGIRVAPTANVDTSLTAFRFDFDNKLEFVSQAVGFRNLGEARHQGVEAEVAWRPAAVRGLELKTAYTYVDTEQRSGQFEG
NELPLAPHHQLNLQGNYRSGDWNWNLNGLYQSASFSDGANTVDENATGSVGRIPAYSVWNAQVTRDFRWNGTKMKAALAL
NNLFDRDYYFRGVDFSQGRMPAPGRAALLTLQMDM

Sequences:

>Translated_675_residues
MKKKLLAVLIPLAFSAHAQETEQLEAVSVSADWLGAATPEAAKKHPGARTVVTEQELAESGARTVEDALRTVPGVRVLDE
SGTGILPNIGVRGLSPLRSEQVLVLVDGMPITLAPYGQTGLSLFPLTLNAVEAIDVARGGVAVHYGPNNVGGVINFVTKR
IPRKPAFTAKETLSIASSGNLLSDTYLRAGGFVSERLGLQAQANLIEGEAERDHSSTSVQNLMLDADWFLTDSANLRAGL
QYYKTENDMPGALTPASYEADREQSTRPLDRFDGDTLRGHVTYSQAFANGAELSWANFAHRSNRQFFFGNSSNADTPSTN
EMSSPREFWVYGSEPRLTFDIDAGVKQKISLGARYLREEVDYVVDSRTLATNAYAVTRDWRFENDAVAAYLSDTFFLLDD
RLKVTPGVRHETVDLYYRNNLTGAETRDTTKDWLPGIDIGYQASDAVFLFANYHKSLRPVQFTQITFGGDLDAERAENYE
AGIRVAPTANVDTSLTAFRFDFDNKLEFVSQAVGFRNLGEARHQGVEAEVAWRPAAVRGLELKTAYTYVDTEQRSGQFEG
NELPLAPHHQLNLQGNYRSGDWNWNLNGLYQSASFSDGANTVDENATGSVGRIPAYSVWNAQVTRDFRWNGTKMKAALAL
NNLFDRDYYFRGVDFSQGRMPAPGRAALLTLQMDM
>Mature_675_residues
MKKKLLAVLIPLAFSAHAQETEQLEAVSVSADWLGAATPEAAKKHPGARTVVTEQELAESGARTVEDALRTVPGVRVLDE
SGTGILPNIGVRGLSPLRSEQVLVLVDGMPITLAPYGQTGLSLFPLTLNAVEAIDVARGGVAVHYGPNNVGGVINFVTKR
IPRKPAFTAKETLSIASSGNLLSDTYLRAGGFVSERLGLQAQANLIEGEAERDHSSTSVQNLMLDADWFLTDSANLRAGL
QYYKTENDMPGALTPASYEADREQSTRPLDRFDGDTLRGHVTYSQAFANGAELSWANFAHRSNRQFFFGNSSNADTPSTN
EMSSPREFWVYGSEPRLTFDIDAGVKQKISLGARYLREEVDYVVDSRTLATNAYAVTRDWRFENDAVAAYLSDTFFLLDD
RLKVTPGVRHETVDLYYRNNLTGAETRDTTKDWLPGIDIGYQASDAVFLFANYHKSLRPVQFTQITFGGDLDAERAENYE
AGIRVAPTANVDTSLTAFRFDFDNKLEFVSQAVGFRNLGEARHQGVEAEVAWRPAAVRGLELKTAYTYVDTEQRSGQFEG
NELPLAPHHQLNLQGNYRSGDWNWNLNGLYQSASFSDGANTVDENATGSVGRIPAYSVWNAQVTRDFRWNGTKMKAALAL
NNLFDRDYYFRGVDFSQGRMPAPGRAALLTLQMDM

Specific function: FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system [H]

COG id: COG4772

COG function: function code P; Outer membrane receptor for Fe3+-dicitrate

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790743, Length=656, Percent_Identity=34.7560975609756, Blast_Score=343, Evalue=3e-95,
Organism=Escherichia coli, GI1788478, Length=703, Percent_Identity=22.0483641536273, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790405, Length=160, Percent_Identity=35.625, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1786798, Length=175, Percent_Identity=30.2857142857143, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR011662
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF07660 STN; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74419; Mature: 74419

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLLAVLIPLAFSAHAQETEQLEAVSVSADWLGAATPEAAKKHPGARTVVTEQELAES
CCCHHEEHHHHHHHCCCCCHHHHEEEEEECCHHCCCCCCHHHHHCCCCCEEEEHHHHHHC
GARTVEDALRTVPGVRVLDESGTGILPNIGVRGLSPLRSEQVLVLVDGMPITLAPYGQTG
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCC
LSLFPLTLNAVEAIDVARGGVAVHYGPNNVGGVINFVTKRIPRKPAFTAKETLSIASSGN
CEEEEEEHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHEEECCCCC
LLSDTYLRAGGFVSERLGLQAQANLIEGEAERDHSSTSVQNLMLDADWFLTDSANLRAGL
CCHHHHHHCCCCHHHHCCCEEECCEECCCCCCCCCHHHHHHEEEECCEEEECCCCHHHCC
QYYKTENDMPGALTPASYEADREQSTRPLDRFDGDTLRGHVTYSQAFANGAELSWANFAH
CEEECCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCEEEEEEEHHHHCCCCCCCHHHHHH
RSNRQFFFGNSSNADTPSTNEMSSPREFWVYGSEPRLTFDIDAGVKQKISLGARYLREEV
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHH
DYVVDSRTLATNAYAVTRDWRFENDAVAAYLSDTFFLLDDRLKVTPGVRHETVDLYYRNN
HHHHCCCEEECCEEEEEECCCCCCCEEEEEECCEEEEEECCEEECCCCCEEEEEEEEECC
LTGAETRDTTKDWLPGIDIGYQASDAVFLFANYHKSLRPVQFTQITFGGDLDAERAENYE
CCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCHHHHCCCC
AGIRVAPTANVDTSLTAFRFDFDNKLEFVSQAVGFRNLGEARHQGVEAEVAWRPAAVRGL
CCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCEEEEECCHHCCCE
ELKTAYTYVDTEQRSGQFEGNELPLAPHHQLNLQGNYRSGDWNWNLNGLYQSASFSDGAN
EEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCC
TVDENATGSVGRIPAYSVWNAQVTRDFRWNGTKMKAALALNNLFDRDYYFRGVDFSQGRM
CCCCCCCCCCCCCCCEEECCCEEEEEEECCCCEEEEHHHHHHHHCCCCEEECCCCCCCCC
PAPGRAALLTLQMDM
CCCCCEEEEEEEECC
>Mature Secondary Structure
MKKKLLAVLIPLAFSAHAQETEQLEAVSVSADWLGAATPEAAKKHPGARTVVTEQELAES
CCCHHEEHHHHHHHCCCCCHHHHEEEEEECCHHCCCCCCHHHHHCCCCCEEEEHHHHHHC
GARTVEDALRTVPGVRVLDESGTGILPNIGVRGLSPLRSEQVLVLVDGMPITLAPYGQTG
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCC
LSLFPLTLNAVEAIDVARGGVAVHYGPNNVGGVINFVTKRIPRKPAFTAKETLSIASSGN
CEEEEEEHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHEEECCCCC
LLSDTYLRAGGFVSERLGLQAQANLIEGEAERDHSSTSVQNLMLDADWFLTDSANLRAGL
CCHHHHHHCCCCHHHHCCCEEECCEECCCCCCCCCHHHHHHEEEECCEEEECCCCHHHCC
QYYKTENDMPGALTPASYEADREQSTRPLDRFDGDTLRGHVTYSQAFANGAELSWANFAH
CEEECCCCCCCCCCCCCCCCCHHHCCCCHHHCCCCCEEEEEEEHHHHCCCCCCCHHHHHH
RSNRQFFFGNSSNADTPSTNEMSSPREFWVYGSEPRLTFDIDAGVKQKISLGARYLREEV
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHH
DYVVDSRTLATNAYAVTRDWRFENDAVAAYLSDTFFLLDDRLKVTPGVRHETVDLYYRNN
HHHHCCCEEECCEEEEEECCCCCCCEEEEEECCEEEEEECCEEECCCCCEEEEEEEEECC
LTGAETRDTTKDWLPGIDIGYQASDAVFLFANYHKSLRPVQFTQITFGGDLDAERAENYE
CCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCHHHHCCCC
AGIRVAPTANVDTSLTAFRFDFDNKLEFVSQAVGFRNLGEARHQGVEAEVAWRPAAVRGL
CCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCEEEEECCHHCCCE
ELKTAYTYVDTEQRSGQFEGNELPLAPHHQLNLQGNYRSGDWNWNLNGLYQSASFSDGAN
EEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCC
TVDENATGSVGRIPAYSVWNAQVTRDFRWNGTKMKAALALNNLFDRDYYFRGVDFSQGRM
CCCCCCCCCCCCCCCEEECCCEEEEEEECCCCEEEEHHHHHHHHCCCCEEECCCCCCCCC
PAPGRAALLTLQMDM
CCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2836368; 7610040; 9278503; 2254251; 2651410 [H]