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The map label for this gene is yceE [C]

Identifier: 74316737

GI number: 74316737

Start: 759364

End: 760527

Strand: Reverse

Name: yceE [C]

Synonym: Tbd_0719

Alternate gene names: 74316737

Gene position: 760527-759364 (Counterclockwise)

Preceding gene: 74316738

Following gene: 74316736

Centisome position: 26.14

GC content: 72.08

Gene sequence:

>1164_bases
ATGAGCCTCGACACGCGGCGCGTCGTCGCCACGATCATGGTCTGCCATTTCGTCGCCGCGTTCGCGGCGCTCGGGATGCC
GCCTTTCTTTGCGCTGATCCTCGAGCGATCGCTGCACAGCGACGCGGCCTACCTGGCGGGCTGGCTCTACATCGTGCCGG
TCTTCTTCACCGCCGTGAGCAGCCCGTGGTGGGGGCGGCTCGCTGACCGCTACGGCAAGAAGCCGCTGCTCCTGCGCGCC
CAGCTCGGCCTCGCGGCGAGCTTCCTGCTCGCCGGCTTCGCGCCCGACGCCGCGACGTTCGCGCTCGCGCTCGCGCTGCA
AGGCCTGCTCGGCGGCACCTTCGCCGCGTCGAACGCGTATCTCGCGACGGTGGTCAGCGGCGCCGCGCTTTCGCGCAGCC
TCGACCTGATGCAATGGTCGGCACGCGCCGCGCTCGTCGCCGCGCCGGCGGGCCTCGGCGTGCTCATGACGATCGAATCG
CCGCTTGAGCTCTACCGTTACCTCGCGCTGCTCCCGCTCGCCGCCGCGGTACTGATCGCGCGCCTGCCGTCGCCGCCGGC
CTCGGCTGCCGCGAAACCCGCGGCGCGCGCGCCGGCCGTTGCACCGGAAGCGCGCGCGAACCAGATCTACGCCGCGCAGT
TCGCGTTCATATTCGCGACCGTGCTGACCTTTCCGTATTTCGTGCCCTTCGCCCAGGCGGCTTCACAGCCGGCGTCGCTC
GCGATGGCCGGGCTGCTGTTCGGCGTCCCGCATCTCGTCTACCTGCTCTGCGCGGTGCCGCTGAGCCGCCGCCTCGTGCC
GGGTCGGCTGCTCGCGACGCTCGCGCTGTCCTTTCTCGTGCTCGCGGGCGCGCTCGCGGCGCAGGCGCTGTTGCCGACAC
TCGCCGGGCTGACCGCCGGGCGCCTGGCGATGGGCCTCGGCATGACGCTCGGCTTCATCAGCCTGCACGCGCTGATCGCC
GCGATCGTGACCCGCGAACGCGCCGGCCGCACCTTCGGCTGGTTCGAGAGCAACGCCAAATGGGGCGCGGTCGGTGCCGG
CGTGATCGCCGGGGCCGCCGTCCAGGCCATCGATTTGCGCGCGCCGTTCTTCATCGGCGCCGCCGTCCTGCTCGCCGCCG
GCGCCTATCTCGGCGCCGTGGCGGCTCAACCGAGAAACCCTTGA

Upstream 100 bases:

>100_bases
ATCTGCTGATCGCGGCGACCCTCGCCGAGAAAAGCGAGACCGGCGCGGCCGACGTCAACAAGTTCTACGGCCGCAGCGCG
CCGAACTTCCTGAAGCCGGC

Downstream 100 bases:

>100_bases
CCCGAGGAGACAGCATGCACTCACACCATCTCGCAAGTGCGATCGACGCCGCGACGCTGGCGCAGCAGGAAGCCGGCCGC
CGCAGCATGGAAACGCTGCT

Product: transport protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLDTRRVVATIMVCHFVAAFAALGMPPFFALILERSLHSDAAYLAGWLYIVPVFFTAVSSPWWGRLADRYGKKPLLLRA
QLGLAASFLLAGFAPDAATFALALALQGLLGGTFAASNAYLATVVSGAALSRSLDLMQWSARAALVAAPAGLGVLMTIES
PLELYRYLALLPLAAAVLIARLPSPPASAAAKPAARAPAVAPEARANQIYAAQFAFIFATVLTFPYFVPFAQAASQPASL
AMAGLLFGVPHLVYLLCAVPLSRRLVPGRLLATLALSFLVLAGALAAQALLPTLAGLTAGRLAMGLGMTLGFISLHALIA
AIVTRERAGRTFGWFESNAKWGAVGAGVIAGAAVQAIDLRAPFFIGAAVLLAAGAYLGAVAAQPRNP

Sequences:

>Translated_387_residues
MSLDTRRVVATIMVCHFVAAFAALGMPPFFALILERSLHSDAAYLAGWLYIVPVFFTAVSSPWWGRLADRYGKKPLLLRA
QLGLAASFLLAGFAPDAATFALALALQGLLGGTFAASNAYLATVVSGAALSRSLDLMQWSARAALVAAPAGLGVLMTIES
PLELYRYLALLPLAAAVLIARLPSPPASAAAKPAARAPAVAPEARANQIYAAQFAFIFATVLTFPYFVPFAQAASQPASL
AMAGLLFGVPHLVYLLCAVPLSRRLVPGRLLATLALSFLVLAGALAAQALLPTLAGLTAGRLAMGLGMTLGFISLHALIA
AIVTRERAGRTFGWFESNAKWGAVGAGVIAGAAVQAIDLRAPFFIGAAVLLAAGAYLGAVAAQPRNP
>Mature_386_residues
SLDTRRVVATIMVCHFVAAFAALGMPPFFALILERSLHSDAAYLAGWLYIVPVFFTAVSSPWWGRLADRYGKKPLLLRAQ
LGLAASFLLAGFAPDAATFALALALQGLLGGTFAASNAYLATVVSGAALSRSLDLMQWSARAALVAAPAGLGVLMTIESP
LELYRYLALLPLAAAVLIARLPSPPASAAAKPAARAPAVAPEARANQIYAAQFAFIFATVLTFPYFVPFAQAASQPASLA
MAGLLFGVPHLVYLLCAVPLSRRLVPGRLLATLALSFLVLAGALAAQALLPTLAGLTAGRLAMGLGMTLGFISLHALIAA
IVTRERAGRTFGWFESNAKWGAVGAGVIAGAAVQAIDLRAPFFIGAAVLLAAGAYLGAVAAQPRNP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40038; Mature: 39907

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDTRRVVATIMVCHFVAAFAALGMPPFFALILERSLHSDAAYLAGWLYIVPVFFTAVS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
SPWWGRLADRYGKKPLLLRAQLGLAASFLLAGFAPDAATFALALALQGLLGGTFAASNAY
CCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHH
LATVVSGAALSRSLDLMQWSARAALVAAPAGLGVLMTIESPLELYRYLALLPLAAAVLIA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
RLPSPPASAAAKPAARAPAVAPEARANQIYAAQFAFIFATVLTFPYFVPFAQAASQPASL
HCCCCCCHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AMAGLLFGVPHLVYLLCAVPLSRRLVPGRLLATLALSFLVLAGALAAQALLPTLAGLTAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAMGLGMTLGFISLHALIAAIVTRERAGRTFGWFESNAKWGAVGAGVIAGAAVQAIDLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
APFFIGAAVLLAAGAYLGAVAAQPRNP
CHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLDTRRVVATIMVCHFVAAFAALGMPPFFALILERSLHSDAAYLAGWLYIVPVFFTAVS
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
SPWWGRLADRYGKKPLLLRAQLGLAASFLLAGFAPDAATFALALALQGLLGGTFAASNAY
CCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHH
LATVVSGAALSRSLDLMQWSARAALVAAPAGLGVLMTIESPLELYRYLALLPLAAAVLIA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
RLPSPPASAAAKPAARAPAVAPEARANQIYAAQFAFIFATVLTFPYFVPFAQAASQPASL
HCCCCCCHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AMAGLLFGVPHLVYLLCAVPLSRRLVPGRLLATLALSFLVLAGALAAQALLPTLAGLTAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAMGLGMTLGFISLHALIAAIVTRERAGRTFGWFESNAKWGAVGAGVIAGAAVQAIDLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
APFFIGAAVLLAAGAYLGAVAAQPRNP
CHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]