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The map label for this gene is dksA [H]

Identifier: 74316709

GI number: 74316709

Start: 731275

End: 731694

Strand: Direct

Name: dksA [H]

Synonym: Tbd_0691

Alternate gene names: 74316709

Gene position: 731275-731694 (Clockwise)

Preceding gene: 74316707

Following gene: 74316710

Centisome position: 25.13

GC content: 58.57

Gene sequence:

>420_bases
ATGGCTGAAACTTTGATGCGCTTTGAGCCCTACAAGGCCAAAAAGGGCGAAGAATACATGAACGCGAAGCAGCTCGAGCA
TTTTCGCAAAATGCTCGACGCCTGGAAAGCCGAGCTCTCGCAGGACATCGACACGACACTGCATTCGATGCAGGACGAGC
AGACCGTTTTTGCCGATCCCAACGATCGCGCGACGCAGGAATCGGACATGGCGCTCGAGCTGCGCAACCGCGATCGCGAG
CGCAAGCTGATCAAGAAGATCAACGAAACCATCGGCAAGATCGACGCCGGGGACTACGGTTATTGCGAGTCGTGCGGCGT
CGAAATCGGCCTCGACCGCCTGCAGGCGCGACCGACCGCGACGCTGTGCATCGACTGCAAGACGCTCGAGGAAATCCGCG
AGCGCCAGGTCGCCAAATAA

Upstream 100 bases:

>100_bases
AGGGCGCGTAATGTCATTTCGGGTTGCGGCAGGAATGCGATTCTGATATTAAGTCGGGGTTGGGCTTGCCCCGGAACTGT
GAATTTTCGAAGAGAACGAG

Downstream 100 bases:

>100_bases
CAGACACCTCATATCCCGGACGACGCCGATGGCCGATAACAGTGAATTCGACCGTTACTACAACGGCCTTTTGTACAGCG
TGATGCGCTGGGAGCAGTTG

Product: TraR/DksA family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MAETLMRFEPYKAKKGEEYMNAKQLEHFRKMLDAWKAELSQDIDTTLHSMQDEQTVFADPNDRATQESDMALELRNRDRE
RKLIKKINETIGKIDAGDYGYCESCGVEIGLDRLQARPTATLCIDCKTLEEIRERQVAK

Sequences:

>Translated_139_residues
MAETLMRFEPYKAKKGEEYMNAKQLEHFRKMLDAWKAELSQDIDTTLHSMQDEQTVFADPNDRATQESDMALELRNRDRE
RKLIKKINETIGKIDAGDYGYCESCGVEIGLDRLQARPTATLCIDCKTLEEIRERQVAK
>Mature_138_residues
AETLMRFEPYKAKKGEEYMNAKQLEHFRKMLDAWKAELSQDIDTTLHSMQDEQTVFADPNDRATQESDMALELRNRDRER
KLIKKINETIGKIDAGDYGYCESCGVEIGLDRLQARPTATLCIDCKTLEEIRERQVAK

Specific function: Dosage-dependent suppressor of a dnaK deletion mutation. It suppressed not only the temperature-sensitive growth but also the filamentous phenotype of the dnaK deletion strain, while the defect of lambda growth is not suppressed [H]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=131, Percent_Identity=64.1221374045801, Blast_Score=182, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR020460
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 16134; Mature: 16003

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01102 ZF_DKSA_1 ; PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLMRFEPYKAKKGEEYMNAKQLEHFRKMLDAWKAELSQDIDTTLHSMQDEQTVFADP
CCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
NDRATQESDMALELRNRDRERKLIKKINETIGKIDAGDYGYCESCGVEIGLDRLQARPTA
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHCHHHHHCCCCC
TLCIDCKTLEEIRERQVAK
EEEECHHHHHHHHHHHCCC
>Mature Secondary Structure 
AETLMRFEPYKAKKGEEYMNAKQLEHFRKMLDAWKAELSQDIDTTLHSMQDEQTVFADP
CCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
NDRATQESDMALELRNRDRERKLIKKINETIGKIDAGDYGYCESCGVEIGLDRLQARPTA
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHCHHHHHCCCCC
TLCIDCKTLEEIRERQVAK
EEEECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]