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The map label for this gene is cya [H]

Identifier: 74316689

GI number: 74316689

Start: 712034

End: 713815

Strand: Direct

Name: cya [H]

Synonym: Tbd_0671

Alternate gene names: 74316689

Gene position: 712034-713815 (Clockwise)

Preceding gene: 74316688

Following gene: 74316693

Centisome position: 24.47

GC content: 67.12

Gene sequence:

>1782_bases
TTGGACGAACCGGCCCGCTGCGCTAGGGTTGAGGGTATCGAGCAGCCAGGAGATCGCGTGCGCCTTCCCATCAGCCTGAA
GATCTTCAGCATCACGACCGCACTCCTTGTGCTGATGGTCGCCGTCACCTGGCTCTCGGTGCTCAATTTCCGGCATCTCA
ACGGCCAGGTCCGCGCGCTTTCGGACTGGTACCTGCCGCTCGAGCAGCAGGTCGCGAGCGTCGAAATCCTGATCCGTCAG
CAGATGGTGCACATGGAGCGGGTCATGGCCGGCATCGAAGCAGCGCGGCCCGACCCCGACTATCTGGCGCGGGAGTCGAC
CAGCTTCGATGCGCGCGGCGTCAACGCCGACCAGATCATCGATTCCTCGCTGCGCTTTCTCGCCGAGGCCGACGCCGAGA
AGGCGATCGATCTCGACCGCGTGACGCTCGCCAAGCTGGCCGAGCAGTTGCCGGCGATCCAGACCGCGCGCCAGCAGTTC
CACCGCACCTTCCGCCTGTTCCAGATCGAGGCCGAGGAAGGCACGCCGCGCTCGCAGAACCTCGTGCGCGACGCTCTGCT
GCGCGAGAAGGACCGGGTCGACGTCGAGATCGGCAAGACCATCGAGCTCCTCGCCAAGCTCACGCAGGACACCGCTGCCG
CGGCCAAGGCCGAGGAGGCGCGCGCGACCACGCTGAACTGGATCGTGACCGGCGTCGCCACCCTGCTGGGTCTCATCTTC
GCGACCTTCGTCACGCGCTCGCTCGTCGACTCGGTCCGGCGCCTGGTAGGCGGCACCCAGGCCGTCGAAGCCGGCGACCT
CGGCGTCGAGATCCGCGTGCGCACGCGCGACGAGATGGCGACGCTGGCAAGCTCGTTCAACCACATGGTCCTCGGCCTGC
GCGAGAAGGAGCGCATCCGCGAAACCTTCGGCCAGTACGTCGACCCGCGCATCGTCAAGAGCCTGCTCGACAACCGCATC
GCGGCGGACCGCGGGCAGCGCGAGGTCATGACCGTGTTCTTCTCCGACCTCGAAGGCTTCACGCGCATGTGCGAGGACCT
CACGCCTGACGCGGCAGTCCGCTTCCTCAACCGCTACTTCGCGATGATGTCCGAGGTCATCCGCGGCCGTCAGGGCATCG
TCGACAAGTACATCGGCGATTCCGTCATGGCGTTCTGGGGTCCGCCGTTCACCGACGCGAAAGGCCACGCGCAGCTCGGC
TGCCTCGCCGCACTCGACCAGATGGCGAAGATGGACGCCTTCCGCGCCAGCCTGCCCGAGCTTTTCGGCGTCAAACACGG
CCTGCCCGACGTCCAGGTGCGCATGGGCATCGCGAGCGGCGAGGTCACCGTCGGCAACATCGGCTCGGAAACCTCGCGCG
GCTACACCGTCATCGGCGACACCGTGAACCTCGCCTCACGCCTCGAGCAGGCCAACAAGTTCTACGGCACGCGCATCCTC
GTCAGCGAGGGCACGCGAAAGCTCGCCGGGGATGACTTCGCCGTCCGCGAAATCGACAGCCTGCGCGTCGCCGGCAAGCT
GCAGCCCGTGCGTGTGTACGAATTGCTCGGCATGGCGAACGAATTGAGCGAAGCGAGCCGGCTGGCCGTCACGGCGTACG
AAGCCGGGCTCGCTCGTTATCGTGCGGAAGACTGGACGGCGGCTGAAGCGGCGTTCAGGGAATGTCTGGCGAAGGCGCCG
GGCGATCGGCCCAGTGCGGTGATGCTGGCGCGGGTCGAGGCGTTCAGGAAAGCACCGCCGGTGGCCGGGTGGAAGGGGGT
CTGGGTGGCGGGGAGCAAGTGA

Upstream 100 bases:

>100_bases
ACGGCTGAAGCGGCTGAAGCGGTCCTACGCGGGCAGACGCTGTCGGACGAGGGGCTGAGCGCTGGCCGGCGCCGACCGCC
GTTTACGGCGTTCCCCGCGC

Downstream 100 bases:

>100_bases
TCTTCTGATACTGAGGCCATCACGCTTCCTCCTGCGGATTCTTCATGCGGCCTGTTCCATCGCATGACATCGCGCTCGAT
CTGCGCGCCATGCTCGGCCA

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MDEPARCARVEGIEQPGDRVRLPISLKIFSITTALLVLMVAVTWLSVLNFRHLNGQVRALSDWYLPLEQQVASVEILIRQ
QMVHMERVMAGIEAARPDPDYLARESTSFDARGVNADQIIDSSLRFLAEADAEKAIDLDRVTLAKLAEQLPAIQTARQQF
HRTFRLFQIEAEEGTPRSQNLVRDALLREKDRVDVEIGKTIELLAKLTQDTAAAAKAEEARATTLNWIVTGVATLLGLIF
ATFVTRSLVDSVRRLVGGTQAVEAGDLGVEIRVRTRDEMATLASSFNHMVLGLREKERIRETFGQYVDPRIVKSLLDNRI
AADRGQREVMTVFFSDLEGFTRMCEDLTPDAAVRFLNRYFAMMSEVIRGRQGIVDKYIGDSVMAFWGPPFTDAKGHAQLG
CLAALDQMAKMDAFRASLPELFGVKHGLPDVQVRMGIASGEVTVGNIGSETSRGYTVIGDTVNLASRLEQANKFYGTRIL
VSEGTRKLAGDDFAVREIDSLRVAGKLQPVRVYELLGMANELSEASRLAVTAYEAGLARYRAEDWTAAEAAFRECLAKAP
GDRPSAVMLARVEAFRKAPPVAGWKGVWVAGSK

Sequences:

>Translated_593_residues
MDEPARCARVEGIEQPGDRVRLPISLKIFSITTALLVLMVAVTWLSVLNFRHLNGQVRALSDWYLPLEQQVASVEILIRQ
QMVHMERVMAGIEAARPDPDYLARESTSFDARGVNADQIIDSSLRFLAEADAEKAIDLDRVTLAKLAEQLPAIQTARQQF
HRTFRLFQIEAEEGTPRSQNLVRDALLREKDRVDVEIGKTIELLAKLTQDTAAAAKAEEARATTLNWIVTGVATLLGLIF
ATFVTRSLVDSVRRLVGGTQAVEAGDLGVEIRVRTRDEMATLASSFNHMVLGLREKERIRETFGQYVDPRIVKSLLDNRI
AADRGQREVMTVFFSDLEGFTRMCEDLTPDAAVRFLNRYFAMMSEVIRGRQGIVDKYIGDSVMAFWGPPFTDAKGHAQLG
CLAALDQMAKMDAFRASLPELFGVKHGLPDVQVRMGIASGEVTVGNIGSETSRGYTVIGDTVNLASRLEQANKFYGTRIL
VSEGTRKLAGDDFAVREIDSLRVAGKLQPVRVYELLGMANELSEASRLAVTAYEAGLARYRAEDWTAAEAAFRECLAKAP
GDRPSAVMLARVEAFRKAPPVAGWKGVWVAGSK
>Mature_593_residues
MDEPARCARVEGIEQPGDRVRLPISLKIFSITTALLVLMVAVTWLSVLNFRHLNGQVRALSDWYLPLEQQVASVEILIRQ
QMVHMERVMAGIEAARPDPDYLARESTSFDARGVNADQIIDSSLRFLAEADAEKAIDLDRVTLAKLAEQLPAIQTARQQF
HRTFRLFQIEAEEGTPRSQNLVRDALLREKDRVDVEIGKTIELLAKLTQDTAAAAKAEEARATTLNWIVTGVATLLGLIF
ATFVTRSLVDSVRRLVGGTQAVEAGDLGVEIRVRTRDEMATLASSFNHMVLGLREKERIRETFGQYVDPRIVKSLLDNRI
AADRGQREVMTVFFSDLEGFTRMCEDLTPDAAVRFLNRYFAMMSEVIRGRQGIVDKYIGDSVMAFWGPPFTDAKGHAQLG
CLAALDQMAKMDAFRASLPELFGVKHGLPDVQVRMGIASGEVTVGNIGSETSRGYTVIGDTVNLASRLEQANKFYGTRIL
VSEGTRKLAGDDFAVREIDSLRVAGKLQPVRVYELLGMANELSEASRLAVTAYEAGLARYRAEDWTAAEAAFRECLAKAP
GDRPSAVMLARVEAFRKAPPVAGWKGVWVAGSK

Specific function: May function as a membrane-localized receptor protein [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Homo sapiens, GI167830411, Length=194, Percent_Identity=32.4742268041237, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI134152694, Length=192, Percent_Identity=29.6875, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI222080083, Length=164, Percent_Identity=31.7073170731707, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4580422, Length=192, Percent_Identity=30.2083333333333, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4504217, Length=188, Percent_Identity=27.1276595744681, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193206632, Length=239, Percent_Identity=29.2887029288703, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI212645052, Length=231, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534659, Length=252, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563954, Length=164, Percent_Identity=29.8780487804878, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71989822, Length=178, Percent_Identity=30.3370786516854, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71989805, Length=178, Percent_Identity=30.3370786516854, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508769, Length=178, Percent_Identity=30.3370786516854, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193207841, Length=146, Percent_Identity=32.8767123287671, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17568383, Length=197, Percent_Identity=32.48730964467, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71982300, Length=208, Percent_Identity=27.4038461538462, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193206054, Length=213, Percent_Identity=30.9859154929577, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24663839, Length=238, Percent_Identity=30.672268907563, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24663843, Length=238, Percent_Identity=30.672268907563, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62484298, Length=177, Percent_Identity=31.638418079096, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62484477, Length=177, Percent_Identity=31.638418079096, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116008008, Length=177, Percent_Identity=31.638418079096, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221330470, Length=213, Percent_Identity=31.4553990610329, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI85725044, Length=153, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221330468, Length=213, Percent_Identity=31.4553990610329, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076872, Length=181, Percent_Identity=30.3867403314917, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574512, Length=181, Percent_Identity=30.3867403314917, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366459, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281366457, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281366455, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI56292422, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI56292424, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666940, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161078020, Length=180, Percent_Identity=31.1111111111111, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647268, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 65536; Mature: 65536

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEPARCARVEGIEQPGDRVRLPISLKIFSITTALLVLMVAVTWLSVLNFRHLNGQVRAL
CCCCHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
SDWYLPLEQQVASVEILIRQQMVHMERVMAGIEAARPDPDYLARESTSFDARGVNADQII
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHH
DSSLRFLAEADAEKAIDLDRVTLAKLAEQLPAIQTARQQFHRTFRLFQIEAEEGTPRSQN
HHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
LVRDALLREKDRVDVEIGKTIELLAKLTQDTAAAAKAEEARATTLNWIVTGVATLLGLIF
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATFVTRSLVDSVRRLVGGTQAVEAGDLGVEIRVRTRDEMATLASSFNHMVLGLREKERIR
HHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHH
ETFGQYVDPRIVKSLLDNRIAADRGQREVMTVFFSDLEGFTRMCEDLTPDAAVRFLNRYF
HHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AMMSEVIRGRQGIVDKYIGDSVMAFWGPPFTDAKGHAQLGCLAALDQMAKMDAFRASLPE
HHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFGVKHGLPDVQVRMGIASGEVTVGNIGSETSRGYTVIGDTVNLASRLEQANKFYGTRIL
HHHHHCCCCCCEEEEEECCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCEEE
VSEGTRKLAGDDFAVREIDSLRVAGKLQPVRVYELLGMANELSEASRLAVTAYEAGLARY
EECCCCHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEDWTAAEAAFRECLAKAPGDRPSAVMLARVEAFRKAPPVAGWKGVWVAGSK
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MDEPARCARVEGIEQPGDRVRLPISLKIFSITTALLVLMVAVTWLSVLNFRHLNGQVRAL
CCCCHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEH
SDWYLPLEQQVASVEILIRQQMVHMERVMAGIEAARPDPDYLARESTSFDARGVNADQII
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHH
DSSLRFLAEADAEKAIDLDRVTLAKLAEQLPAIQTARQQFHRTFRLFQIEAEEGTPRSQN
HHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHH
LVRDALLREKDRVDVEIGKTIELLAKLTQDTAAAAKAEEARATTLNWIVTGVATLLGLIF
HHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATFVTRSLVDSVRRLVGGTQAVEAGDLGVEIRVRTRDEMATLASSFNHMVLGLREKERIR
HHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHH
ETFGQYVDPRIVKSLLDNRIAADRGQREVMTVFFSDLEGFTRMCEDLTPDAAVRFLNRYF
HHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AMMSEVIRGRQGIVDKYIGDSVMAFWGPPFTDAKGHAQLGCLAALDQMAKMDAFRASLPE
HHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFGVKHGLPDVQVRMGIASGEVTVGNIGSETSRGYTVIGDTVNLASRLEQANKFYGTRIL
HHHHHCCCCCCEEEEEECCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCEEE
VSEGTRKLAGDDFAVREIDSLRVAGKLQPVRVYELLGMANELSEASRLAVTAYEAGLARY
EECCCCHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEDWTAAEAAFRECLAKAPGDRPSAVMLARVEAFRKAPPVAGWKGVWVAGSK
HCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7601856 [H]