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The map label for this gene is tsr [H]

Identifier: 74316678

GI number: 74316678

Start: 699960

End: 701720

Strand: Direct

Name: tsr [H]

Synonym: Tbd_0660

Alternate gene names: 74316678

Gene position: 699960-701720 (Clockwise)

Preceding gene: 74316676

Following gene: 74316684

Centisome position: 24.06

GC content: 69.17

Gene sequence:

>1761_bases
ATGTGCGCCCGGCCGGACTGTCACGCGTCACGAGGCTGTCACGCGGCGAGGCTACAGTGCGCCCGCTGGGGCGACTGCGC
CTCGATGCATCGAGGGAGAACCATGACGCTCGTCAACATGAAAATCGGCACGCGGCTCGGCACCGGCTTCGGCGCGGTGC
TGCTGCTCACGCTCGCGGTTGCGGGCCTCGGTCTCGCGTACCTGTCGCAGATCCAGCGGCACGTCGACGACGTAGCCGGC
AGCCGCATGGGCAAGATCAAACTGGTCAATGGCATGCGGGACGCGATGCAGAGCGGCGCGGTCGCCGTGCGCAATCTCGT
TCTGCTCACCGACGAGGGCGCGATGGCGGAGGAAGCGCAACGCTTCCTCGCGCACCGGGCGCGCTACGCCGACGCCGCGG
CGAAACTCGCCACCGCGGTCAGGAGTCCGGCGGAAACGTCGGTGTACGACAAGATCGCGGCTGCCCGCGCGCGAACCGAG
CCTGCGCTCGACAAGGTCCGCGAGTTCGCGATGGGCAACCCGCTCGAGGCCACGCGTGTGCTCGTCGAGGAGGTGCGCCC
GCTGCAGCAGCAATGGCTCGCCGCGCTCGAGGAGATGGCGGCGCTGCAGGAGCGCGGGGCTGCCGTGGCCATGGTCGACG
CGGCCGACGCCTACGCGAACGCGTTTTCGATCCTGCTCGTGCTGTCCCTTGGCGCTGTCGTCACCGGCGCTGGCGTCGCC
TGGCGGATCACGCGCTCGGTCACCGAACCGGTGCGGAAAGCCGTCGCGCTCGCGCGCTCGGTGGCTGGCGGCGACCTGAC
CGCGCGCGGCGAAAGCCGTGCGGACGACGAATTCGGTCAGTTGCAGCGCGCGCTCACCGGCATGACCGCGAGTCTGGCGG
GAATCGTCGCGGAAGTGCGCCACACGACCGACACCATCGCCGTCGCCTCGCGCGAAATCGCCTCCGGCAACGCCGACCTC
TCGTCTCGCACCGAATCGCAGGCCTCGAGCCTCGAAGAGACCGCGAGCTCGATGGAAGAACTGACCAGCACCGTACGGCA
GAACGCCGAGAACGCCCGCCAGGCCAACCAGCTCGTCGTCTCCACCGCCGACGTCGCCGTCAAGGGTGGCGAAGTCGTCG
GCCAGGTCGTCGACACCATGGCCTCCATCAAGGACAGCTCGCGGAAGATCTCCGACATCATCGGCGTCATCGACGGCATC
GCCTTCCAGACCAACATCCTTGCGCTCAACGCCGCCGTCGAAGCGGCGCGTGCCGGCGAGCAGGGCAGGGGCTTCGCCGT
CGTCGCCAGCGAAGTCAGGAATCTTGCCCAGCGCAGCGCCGGTGCCGCCAAGGAAATCAAGTCCCTGATCGAAGACTCCG
TCGGCAAGGTCGACGCCGGCAGCAAGCTCGTCGACGAAGCCGGCAAGACCATGGACGAGATCGTCAGCTCGGTCAAACGC
GTCACCGACATCATGAGCGAGATCGCCGCCGCGAGCCAGGAGCAGAGCGCCGGGATCGAGCAGGTCAACCAGGCCGTCGG
CCAGATGGACGAGATGACCCAGCAGAATGCCGCGCTCGTCGAAGAGGCAGCCGCTGCGGCCGAGAGCCTGCAGGAGCAGG
CGGCGAAGCTCGCCGACGCGGTCAGCGTGTTCAAGCTCGATGGCGGCGATGGCGAGCGGCTCGGCGTGGCGGCCCCGGTC
GCTCGGGCTTCGGTCCGACGCGCCACATCCCTACAGGTGGCCAAGGCCCGCGCGCCCAGGCTCGCGCTCGTCGCCCGCTG
A

Upstream 100 bases:

>100_bases
TTCTCCTTGTTGATGGGTTACAGGCTGCCGGTCGGCAACCGGGCCGCCGGCCTTCTCAAAGCGTAGGCGAAGCCGCCGGC
GTGGCAAGCGCGCCGGGTCG

Downstream 100 bases:

>100_bases
AGGCGCGACCGCTGTAAATCTCCGGGCCGCTGCACGCGGCGGCGAGGTCTCAGCGCGGCTTCAGCGTCGCCGCCCGTGGA
ACGACGAGCCTGACGTAGTC

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MCARPDCHASRGCHAARLQCARWGDCASMHRGRTMTLVNMKIGTRLGTGFGAVLLLTLAVAGLGLAYLSQIQRHVDDVAG
SRMGKIKLVNGMRDAMQSGAVAVRNLVLLTDEGAMAEEAQRFLAHRARYADAAAKLATAVRSPAETSVYDKIAAARARTE
PALDKVREFAMGNPLEATRVLVEEVRPLQQQWLAALEEMAALQERGAAVAMVDAADAYANAFSILLVLSLGAVVTGAGVA
WRITRSVTEPVRKAVALARSVAGGDLTARGESRADDEFGQLQRALTGMTASLAGIVAEVRHTTDTIAVASREIASGNADL
SSRTESQASSLEETASSMEELTSTVRQNAENARQANQLVVSTADVAVKGGEVVGQVVDTMASIKDSSRKISDIIGVIDGI
AFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAGAAKEIKSLIEDSVGKVDAGSKLVDEAGKTMDEIVSSVKR
VTDIMSEIAAASQEQSAGIEQVNQAVGQMDEMTQQNAALVEEAAAAAESLQEQAAKLADAVSVFKLDGGDGERLGVAAPV
ARASVRRATSLQVAKARAPRLALVAR

Sequences:

>Translated_586_residues
MCARPDCHASRGCHAARLQCARWGDCASMHRGRTMTLVNMKIGTRLGTGFGAVLLLTLAVAGLGLAYLSQIQRHVDDVAG
SRMGKIKLVNGMRDAMQSGAVAVRNLVLLTDEGAMAEEAQRFLAHRARYADAAAKLATAVRSPAETSVYDKIAAARARTE
PALDKVREFAMGNPLEATRVLVEEVRPLQQQWLAALEEMAALQERGAAVAMVDAADAYANAFSILLVLSLGAVVTGAGVA
WRITRSVTEPVRKAVALARSVAGGDLTARGESRADDEFGQLQRALTGMTASLAGIVAEVRHTTDTIAVASREIASGNADL
SSRTESQASSLEETASSMEELTSTVRQNAENARQANQLVVSTADVAVKGGEVVGQVVDTMASIKDSSRKISDIIGVIDGI
AFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAGAAKEIKSLIEDSVGKVDAGSKLVDEAGKTMDEIVSSVKR
VTDIMSEIAAASQEQSAGIEQVNQAVGQMDEMTQQNAALVEEAAAAAESLQEQAAKLADAVSVFKLDGGDGERLGVAAPV
ARASVRRATSLQVAKARAPRLALVAR
>Mature_586_residues
MCARPDCHASRGCHAARLQCARWGDCASMHRGRTMTLVNMKIGTRLGTGFGAVLLLTLAVAGLGLAYLSQIQRHVDDVAG
SRMGKIKLVNGMRDAMQSGAVAVRNLVLLTDEGAMAEEAQRFLAHRARYADAAAKLATAVRSPAETSVYDKIAAARARTE
PALDKVREFAMGNPLEATRVLVEEVRPLQQQWLAALEEMAALQERGAAVAMVDAADAYANAFSILLVLSLGAVVTGAGVA
WRITRSVTEPVRKAVALARSVAGGDLTARGESRADDEFGQLQRALTGMTASLAGIVAEVRHTTDTIAVASREIASGNADL
SSRTESQASSLEETASSMEELTSTVRQNAENARQANQLVVSTADVAVKGGEVVGQVVDTMASIKDSSRKISDIIGVIDGI
AFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAGAAKEIKSLIEDSVGKVDAGSKLVDEAGKTMDEIVSSVKR
VTDIMSEIAAASQEQSAGIEQVNQAVGQMDEMTQQNAALVEEAAAAAESLQEQAAKLADAVSVFKLDGGDGERLGVAAPV
ARASVRRATSLQVAKARAPRLALVAR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=380, Percent_Identity=55.2631578947368, Blast_Score=336, Evalue=3e-93,
Organism=Escherichia coli, GI1788195, Length=307, Percent_Identity=62.5407166123778, Blast_Score=329, Evalue=3e-91,
Organism=Escherichia coli, GI1787690, Length=399, Percent_Identity=49.1228070175439, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1788194, Length=324, Percent_Identity=54.0123456790123, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI1789453, Length=320, Percent_Identity=38.125, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 61309; Mature: 61309

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCARPDCHASRGCHAARLQCARWGDCASMHRGRTMTLVNMKIGTRLGTGFGAVLLLTLAV
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEEEEEECCCHHCCHHHHHHHHHHHH
AGLGLAYLSQIQRHVDDVAGSRMGKIKLVNGMRDAMQSGAVAVRNLVLLTDEGAMAEEAQ
HHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCHHHHHHEEEEECCCCHHHHHH
RFLAHRARYADAAAKLATAVRSPAETSVYDKIAAARARTEPALDKVREFAMGNPLEATRV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHH
LVEEVRPLQQQWLAALEEMAALQERGAAVAMVDAADAYANAFSILLVLSLGAVVTGAGVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHH
WRITRSVTEPVRKAVALARSVAGGDLTARGESRADDEFGQLQRALTGMTASLAGIVAEVR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HTTDTIAVASREIASGNADLSSRTESQASSLEETASSMEELTSTVRQNAENARQANQLVV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
STADVAVKGGEVVGQVVDTMASIKDSSRKISDIIGVIDGIAFQTNILALNAAVEAARAGE
EHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVASEVRNLAQRSAGAAKEIKSLIEDSVGKVDAGSKLVDEAGKTMDEIVSSVKR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHH
VTDIMSEIAAASQEQSAGIEQVNQAVGQMDEMTQQNAALVEEAAAAAESLQEQAAKLADA
HHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVFKLDGGDGERLGVAAPVARASVRRATSLQVAKARAPRLALVAR
HHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MCARPDCHASRGCHAARLQCARWGDCASMHRGRTMTLVNMKIGTRLGTGFGAVLLLTLAV
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEEEEEECCCHHCCHHHHHHHHHHHH
AGLGLAYLSQIQRHVDDVAGSRMGKIKLVNGMRDAMQSGAVAVRNLVLLTDEGAMAEEAQ
HHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCHHHHHHEEEEECCCCHHHHHH
RFLAHRARYADAAAKLATAVRSPAETSVYDKIAAARARTEPALDKVREFAMGNPLEATRV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHH
LVEEVRPLQQQWLAALEEMAALQERGAAVAMVDAADAYANAFSILLVLSLGAVVTGAGVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHH
WRITRSVTEPVRKAVALARSVAGGDLTARGESRADDEFGQLQRALTGMTASLAGIVAEVR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HTTDTIAVASREIASGNADLSSRTESQASSLEETASSMEELTSTVRQNAENARQANQLVV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
STADVAVKGGEVVGQVVDTMASIKDSSRKISDIIGVIDGIAFQTNILALNAAVEAARAGE
EHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVASEVRNLAQRSAGAAKEIKSLIEDSVGKVDAGSKLVDEAGKTMDEIVSSVKR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHH
VTDIMSEIAAASQEQSAGIEQVNQAVGQMDEMTQQNAALVEEAAAAAESLQEQAAKLADA
HHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVFKLDGGDGERLGVAAPVARASVRRATSLQVAKARAPRLALVAR
HHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]