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The map label for this gene is aroC

Identifier: 74316684

GI number: 74316684

Start: 706654

End: 707754

Strand: Direct

Name: aroC

Synonym: Tbd_0666

Alternate gene names: 74316684

Gene position: 706654-707754 (Clockwise)

Preceding gene: 74316678

Following gene: 74316688

Centisome position: 24.29

GC content: 68.12

Gene sequence:

>1101_bases
ATGTCTGGCAGCACCCTCGGCAAACTGTTCTGCGTGACCGTATTCGGCGAGTCGCACGGCCCCGCGATCGGCTGCGTCGT
CGACGGCTGCCCGCCCGGCATGACGCTGGGCGAATCCGACATCCAGCACGATCTCGACCGGCGCAAGCCCGGCACCTCCC
GCCACGTCACGCAACGTCGCGAATCCGACACGGCCGAGATTCTTTCCGGCGTCTACGAAGGCAGGACCACCGGCACGCCG
ATCGCGCTGCTGATCCGCAACGAGGACCAGCGCAGCAAGGACTACGGAAACATTGCCGCGACCTTCCGGCCGGGGCACGC
CGACTATACCTATACGCAGAAATACGGCTTTCGCGACCCGCGGGGAGGCGGCCGTTCGTCTGCGCGGCTGACTGCGCCGA
TCGTCGGCGCCGGCGCCATCGCGAAGAAGTGGCTGAAGGAAAAATACGGCATCGTGATCCGCGGCTACATGAGCGCGCTC
GGCCCGCTCGACATTCCCTTCGAATCCTGGGATGAAGTCGACAACAACGCCTTCTTCTCGCCCAACGCCGCGATCGTGCC
CGAACTCGAGCAATACATGGACGCGCTGAGAAAATCCGGCGACTCGGTCGGTGCGCGCGTCAGCGTCGTCGCCGAGAACG
TGCCGCCCGGCTGGGGCGAGCCGCTGTACGACAAGCTCGACGCCGACCTCGCCCACGCGCTGATGGGCCTGAACGCCGTC
AAGGGCGTCGAGATCGGCGACGGCATGCAGGCCGCGCGACAGCTCGGCACCGAGCATCGCGACGAGATCACCCCCGCGGG
ATTTCTCTCCAACCATGCCGGCGGCGTGCTCGGCGGCATCTCGTCGGGGCAGGCGATCGTCGCCCACGTCGCGATCAAGC
CGACCTCGTCGATGCGCCTGCCCGGGCGCTCGGTCGACCTCGATGGCCAGCCGATCGAGGTCGTCACCCACGGCCGGCAC
GACCCCTGCGTCGGCATCCGCGCGACGCCGATCGTCGAGGCGCTGACCGCGATCGTGCTGATGGACCATGCGCTGCGCCA
CCGCGCGCAGTGCGGCGATGTCGCGAGCGGCGTTCCGATCGTGCCCGCACGGCTGGACTGA

Upstream 100 bases:

>100_bases
GGGCCAAGGTTCCGCCTACCGCCTCGCGCGGCGGCCCGGCCACGGCCTGCGCCTGTGCTAGACTCCGCCGCATTCCCAAG
GTTTTTTCGCGGCTCATTCC

Downstream 100 bases:

>100_bases
GCCGACCCGGCGCGCGCCCGGCCGTGGGCGCTACGGTGATACCGCCGTCGGAAGCCTTCCCGTCTCGCGCCTGAACACGC
TTTTGGCGAACTGCGGCGGA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSGSTLGKLFCVTVFGESHGPAIGCVVDGCPPGMTLGESDIQHDLDRRKPGTSRHVTQRRESDTAEILSGVYEGRTTGTP
IALLIRNEDQRSKDYGNIAATFRPGHADYTYTQKYGFRDPRGGGRSSARLTAPIVGAGAIAKKWLKEKYGIVIRGYMSAL
GPLDIPFESWDEVDNNAFFSPNAAIVPELEQYMDALRKSGDSVGARVSVVAENVPPGWGEPLYDKLDADLAHALMGLNAV
KGVEIGDGMQAARQLGTEHRDEITPAGFLSNHAGGVLGGISSGQAIVAHVAIKPTSSMRLPGRSVDLDGQPIEVVTHGRH
DPCVGIRATPIVEALTAIVLMDHALRHRAQCGDVASGVPIVPARLD

Sequences:

>Translated_366_residues
MSGSTLGKLFCVTVFGESHGPAIGCVVDGCPPGMTLGESDIQHDLDRRKPGTSRHVTQRRESDTAEILSGVYEGRTTGTP
IALLIRNEDQRSKDYGNIAATFRPGHADYTYTQKYGFRDPRGGGRSSARLTAPIVGAGAIAKKWLKEKYGIVIRGYMSAL
GPLDIPFESWDEVDNNAFFSPNAAIVPELEQYMDALRKSGDSVGARVSVVAENVPPGWGEPLYDKLDADLAHALMGLNAV
KGVEIGDGMQAARQLGTEHRDEITPAGFLSNHAGGVLGGISSGQAIVAHVAIKPTSSMRLPGRSVDLDGQPIEVVTHGRH
DPCVGIRATPIVEALTAIVLMDHALRHRAQCGDVASGVPIVPARLD
>Mature_365_residues
SGSTLGKLFCVTVFGESHGPAIGCVVDGCPPGMTLGESDIQHDLDRRKPGTSRHVTQRRESDTAEILSGVYEGRTTGTPI
ALLIRNEDQRSKDYGNIAATFRPGHADYTYTQKYGFRDPRGGGRSSARLTAPIVGAGAIAKKWLKEKYGIVIRGYMSALG
PLDIPFESWDEVDNNAFFSPNAAIVPELEQYMDALRKSGDSVGARVSVVAENVPPGWGEPLYDKLDADLAHALMGLNAVK
GVEIGDGMQAARQLGTEHRDEITPAGFLSNHAGGVLGGISSGQAIVAHVAIKPTSSMRLPGRSVDLDGQPIEVVTHGRHD
PCVGIRATPIVEALTAIVLMDHALRHRAQCGDVASGVPIVPARLD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=62.6740947075209, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=41.9618528610354, Blast_Score=282, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_THIDA (Q3SL02)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314424.1
- HSSP:   P63611
- ProteinModelPortal:   Q3SL02
- SMR:   Q3SL02
- STRING:   Q3SL02
- GeneID:   3672631
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0666
- NMPDR:   fig|292415.3.peg.631
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q3SL02
- ProtClustDB:   PRK05382
- BioCyc:   TDEN292415:TBD_0666-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38919; Mature: 38787

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSTLGKLFCVTVFGESHGPAIGCVVDGCPPGMTLGESDIQHDLDRRKPGTSRHVTQRR
CCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHH
ESDTAEILSGVYEGRTTGTPIALLIRNEDQRSKDYGNIAATFRPGHADYTYTQKYGFRDP
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEHHCCCCCCC
RGGGRSSARLTAPIVGAGAIAKKWLKEKYGIVIRGYMSALGPLDIPFESWDEVDNNAFFS
CCCCCCCCEEECCEECCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHCCCCCEEEC
PNAAIVPELEQYMDALRKSGDSVGARVSVVAENVPPGWGEPLYDKLDADLAHALMGLNAV
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGMQAARQLGTEHRDEITPAGFLSNHAGGVLGGISSGQAIVAHVAIKPTSSMRL
CCCCCCCHHHHHHHHCCHHHHHCCCCHHHHCCCCCEEECCCCCCEEEEEEEECCCCCCCC
PGRSVDLDGQPIEVVTHGRHDPCVGIRATPIVEALTAIVLMDHALRHRAQCGDVASGVPI
CCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VPARLD
CCCCCC
>Mature Secondary Structure 
SGSTLGKLFCVTVFGESHGPAIGCVVDGCPPGMTLGESDIQHDLDRRKPGTSRHVTQRR
CCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHH
ESDTAEILSGVYEGRTTGTPIALLIRNEDQRSKDYGNIAATFRPGHADYTYTQKYGFRDP
CCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEHHCCCCCCC
RGGGRSSARLTAPIVGAGAIAKKWLKEKYGIVIRGYMSALGPLDIPFESWDEVDNNAFFS
CCCCCCCCEEECCEECCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHCCCCCEEEC
PNAAIVPELEQYMDALRKSGDSVGARVSVVAENVPPGWGEPLYDKLDADLAHALMGLNAV
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGMQAARQLGTEHRDEITPAGFLSNHAGGVLGGISSGQAIVAHVAIKPTSSMRL
CCCCCCCHHHHHHHHCCHHHHHCCCCHHHHCCCCCEEECCCCCCEEEEEEEECCCCCCCC
PGRSVDLDGQPIEVVTHGRHDPCVGIRATPIVEALTAIVLMDHALRHRAQCGDVASGVPI
CCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VPARLD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA