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The map label for this gene is hprK [H]

Identifier: 74316548

GI number: 74316548

Start: 555878

End: 556816

Strand: Reverse

Name: hprK [H]

Synonym: Tbd_0530

Alternate gene names: 74316548

Gene position: 556816-555878 (Counterclockwise)

Preceding gene: 74316549

Following gene: 74316547

Centisome position: 19.14

GC content: 66.35

Gene sequence:

>939_bases
ATGGAGGAAGGCGCGCGCGTTTCGGTCGAGACCCTGTTCCGCGACATGGCGGGACAAGTCGACCTGCAATGGGCCGCGGC
CCAGCAGGGCGGCGAACGCAGCCTTTCCTCGGAGCCGACCGTCGCGCTGATCGGCCACCTCAACTTCGTCCACCCCAACC
GCATCCAGGTGCTCGGCAACGCCGAGATGAACTACCTGCGCAGCCTCACCGACATCGGGCTGCGCGACGCCATCGCCCAT
CTGTTCTCGAGCGAACTCGCCGCCGTCGTCGTTGCCAACGGCGAGGGCGTGCCCGCTGTGCTGCTCGAGGGCGCCGAGCG
CACCCAGACGCCGCTTTTCACGTCGTCGCTGCCAAGCCCGGTATTGATGTCGACGCTCGGCCACTATCTGCGGCAGCAGC
TCGCCGAGACCGTATCGGTCCACGGCGTGTTTCTCGAAGTGCTCGGGACGGGCATCCTGATCAAGGGCGACGCCGGCGTC
GGCAAAAGCGAACTCGCCCTCGAGCTGATCACGCGCGGCCATCGCCTGGTCGCCGATGACGTCGTCGAACTCAAGCACGT
CGCGCCCGAAACGCTCGAAGGCAGCTGCCCGCCACTGATCCGCGACTTCCTCGAGGTGCGGGGCCTCGGCATCCTCAACA
TCCGCTTCCTGTTCGGCGAAATGGCGGTCAAGCCGCACCAGAACCTGCGGCTCATCGTCGAACTCGTGCATCCTGAGGAG
ATCGGCGAGGTCGGGCTCAACCGCCTCGACATGGTAGCGTCGACGCAGACGATACTCGGCGTCGCGATTCCCAAGGTCCG
CGTGCCGGTCGCGGCAGGCCGCAACCTCGCGGTCCTGGTCGAGGTCGCGGTGCGCAACCACATCCTCAAGACGCGTGGGA
TCAACCCGGTCGAGCAATTCATCAAGCGCCAGCAGGCGGCGATCAACGGGGAAGACTGA

Upstream 100 bases:

>100_bases
GCAGTTGTTCGGTGACGAAGGCATGCGTGCCCGCATGTTCGAAGCCGCCTCGCCTTCGGATCTGATCGCACTGGTCGCGG
CCTGGTCCGGTTAGCGGCGC

Downstream 100 bases:

>100_bases
TGCAGATCGTTCTGGTGTCCGGACTGTCGGGCTCGGGCAAGAGCATCGCCACTGCAGTGCTCGAAGACGTCGGCTACTAC
TGCGTCGACAACCTGCCGCT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MEEGARVSVETLFRDMAGQVDLQWAAAQQGGERSLSSEPTVALIGHLNFVHPNRIQVLGNAEMNYLRSLTDIGLRDAIAH
LFSSELAAVVVANGEGVPAVLLEGAERTQTPLFTSSLPSPVLMSTLGHYLRQQLAETVSVHGVFLEVLGTGILIKGDAGV
GKSELALELITRGHRLVADDVVELKHVAPETLEGSCPPLIRDFLEVRGLGILNIRFLFGEMAVKPHQNLRLIVELVHPEE
IGEVGLNRLDMVASTQTILGVAIPKVRVPVAAGRNLAVLVEVAVRNHILKTRGINPVEQFIKRQQAAINGED

Sequences:

>Translated_312_residues
MEEGARVSVETLFRDMAGQVDLQWAAAQQGGERSLSSEPTVALIGHLNFVHPNRIQVLGNAEMNYLRSLTDIGLRDAIAH
LFSSELAAVVVANGEGVPAVLLEGAERTQTPLFTSSLPSPVLMSTLGHYLRQQLAETVSVHGVFLEVLGTGILIKGDAGV
GKSELALELITRGHRLVADDVVELKHVAPETLEGSCPPLIRDFLEVRGLGILNIRFLFGEMAVKPHQNLRLIVELVHPEE
IGEVGLNRLDMVASTQTILGVAIPKVRVPVAAGRNLAVLVEVAVRNHILKTRGINPVEQFIKRQQAAINGED
>Mature_312_residues
MEEGARVSVETLFRDMAGQVDLQWAAAQQGGERSLSSEPTVALIGHLNFVHPNRIQVLGNAEMNYLRSLTDIGLRDAIAH
LFSSELAAVVVANGEGVPAVLLEGAERTQTPLFTSSLPSPVLMSTLGHYLRQQLAETVSVHGVFLEVLGTGILIKGDAGV
GKSELALELITRGHRLVADDVVELKHVAPETLEGSCPPLIRDFLEVRGLGILNIRFLFGEMAVKPHQNLRLIVELVHPEE
IGEVGLNRLDMVASTQTILGVAIPKVRVPVAAGRNLAVLVEVAVRNHILKTRGINPVEQFIKRQQAAINGED

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 33709; Mature: 33709

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEGARVSVETLFRDMAGQVDLQWAAAQQGGERSLSSEPTVALIGHLNFVHPNRIQVLGN
CCCCCEEEHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCCEEEEECEEEECCCEEEEEEC
AEMNYLRSLTDIGLRDAIAHLFSSELAAVVVANGEGVPAVLLEGAERTQTPLFTSSLPSP
CHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCHHCCCCCCCCCCCH
VLMSTLGHYLRQQLAETVSVHGVFLEVLGTGILIKGDAGVGKSELALELITRGHRLVADD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHH
VVELKHVAPETLEGSCPPLIRDFLEVRGLGILNIRFLFGEMAVKPHQNLRLIVELVHPEE
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCHHH
IGEVGLNRLDMVASTQTILGVAIPKVRVPVAAGRNLAVLVEVAVRNHILKTRGINPVEQF
HHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEHHHHHHHHHHHHCCCCHHHHH
IKRQQAAINGED
HHHHHHHCCCCC
>Mature Secondary Structure
MEEGARVSVETLFRDMAGQVDLQWAAAQQGGERSLSSEPTVALIGHLNFVHPNRIQVLGN
CCCCCEEEHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCCEEEEECEEEECCCEEEEEEC
AEMNYLRSLTDIGLRDAIAHLFSSELAAVVVANGEGVPAVLLEGAERTQTPLFTSSLPSP
CHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCCCCEECCCCHHCCCCCCCCCCCH
VLMSTLGHYLRQQLAETVSVHGVFLEVLGTGILIKGDAGVGKSELALELITRGHRLVADD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHH
VVELKHVAPETLEGSCPPLIRDFLEVRGLGILNIRFLFGEMAVKPHQNLRLIVELVHPEE
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCHHH
IGEVGLNRLDMVASTQTILGVAIPKVRVPVAAGRNLAVLVEVAVRNHILKTRGINPVEQF
HHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEHHHHHHHHHHHHCCCCHHHHH
IKRQQAAINGED
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]