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The map label for this gene is coaX

Identifier: 74316479

GI number: 74316479

Start: 484682

End: 485416

Strand: Direct

Name: coaX

Synonym: Tbd_0461

Alternate gene names: 74316479

Gene position: 484682-485416 (Clockwise)

Preceding gene: 74316478

Following gene: 74316480

Centisome position: 16.66

GC content: 69.39

Gene sequence:

>735_bases
ATGAGCGGATGCCGTATCTTGCTCGACGCCGGTAACTCCAGCCTCAAGTGGGCCGTCGTCGAGGACGGAACATGGCTCGC
CCGCGGCCGCAGCGACTACAGTGACCTGTCGGCCGTAGAGGCGGAATTGGACGCGGGGTCGGAATGCTTCATCGCGAGCG
TGGCAAGCCGGGTCTACGAGGAGAAGCTGGCGGCCCTGCTGACGGCGGCCGGCTGTTCGGCCGTCTGGCTCAAAAGCGAA
GCGGCTTTCGACGACGTGACGAACGACTATCGTGATCCGACACAGCTCGGCGTGGATCGCTGGATGGGTCTGGTCGCGGC
GCGCGCGCGCCGACGCGCCCCGACGCTCGTCGTGTCGGCCGGAACGGCGATGACGGTCGACGCCTTGTCCGGCGACGGCA
GCTTCCTCGGTGGACTCATCGTGCCGGGGGTGGCGTTGATGCAGCGGTCCCTGCAACAGGGGACGGCGGGCGGCGCAGCC
GCCGGTGGCGCGTGGCAGGCGTTTCCCCGTTGTACTGCGGATGCGGCATATAGCGGAATCATCGCCGCGCTATGCGGGGC
CGTGGAGGGCCAGCACGTGCGGCTGGCGGCGCATGAGGGCATCTCGCCGGCCTGCCTGATCACCGGCGGCGGGGCCGAGA
CACTGCTTCCGCATTTGGGGGTCGACGCCGAGCACGTGCCCACGCTCGTGCTCGAAGGTATCGAGCGCGTCGCGCGCGCA
GGGGGGCGAGGATGA

Upstream 100 bases:

>100_bases
CCGGCGTCGACGAAACGGGCGCCTTCCTGTTGCAGGCGCCAAACGCGAGCGTGGCGCCCTATAGCGGTGGCGAAATCAGC
CTGCGTCTGGACGCGCGCCG

Downstream 100 bases:

>100_bases
AACGTCTGGCATGGTCCCTGCTGATCGCGAACGTGCTCGCGGCCGGTTTCTTCCTCGCACGCGATCACTGGCCGACGGCG
AGCGCGCCGCACAGTGCACC

Product: putative transcriptional acitvator, Baf

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSGCRILLDAGNSSLKWAVVEDGTWLARGRSDYSDLSAVEAELDAGSECFIASVASRVYEEKLAALLTAAGCSAVWLKSE
AAFDDVTNDYRDPTQLGVDRWMGLVAARARRRAPTLVVSAGTAMTVDALSGDGSFLGGLIVPGVALMQRSLQQGTAGGAA
AGGAWQAFPRCTADAAYSGIIAALCGAVEGQHVRLAAHEGISPACLITGGGAETLLPHLGVDAEHVPTLVLEGIERVARA
GGRG

Sequences:

>Translated_244_residues
MSGCRILLDAGNSSLKWAVVEDGTWLARGRSDYSDLSAVEAELDAGSECFIASVASRVYEEKLAALLTAAGCSAVWLKSE
AAFDDVTNDYRDPTQLGVDRWMGLVAARARRRAPTLVVSAGTAMTVDALSGDGSFLGGLIVPGVALMQRSLQQGTAGGAA
AGGAWQAFPRCTADAAYSGIIAALCGAVEGQHVRLAAHEGISPACLITGGGAETLLPHLGVDAEHVPTLVLEGIERVARA
GGRG
>Mature_243_residues
SGCRILLDAGNSSLKWAVVEDGTWLARGRSDYSDLSAVEAELDAGSECFIASVASRVYEEKLAALLTAAGCSAVWLKSEA
AFDDVTNDYRDPTQLGVDRWMGLVAARARRRAPTLVVSAGTAMTVDALSGDGSFLGGLIVPGVALMQRSLQQGTAGGAAA
GGAWQAFPRCTADAAYSGIIAALCGAVEGQHVRLAAHEGISPACLITGGGAETLLPHLGVDAEHVPTLVLEGIERVARAG
GRG

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_THIDA (Q3SLJ6)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314219.1
- ProteinModelPortal:   Q3SLJ6
- SMR:   Q3SLJ6
- STRING:   Q3SLJ6
- GeneID:   3673094
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0461
- NMPDR:   fig|292415.3.peg.22
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   CRIVSVR
- BioCyc:   TDEN292415:TBD_0461-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 25011; Mature: 24879

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: ACT_SITE 99-99 BINDING 90-90 BINDING 122-122 BINDING 172-172

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGCRILLDAGNSSLKWAVVEDGTWLARGRSDYSDLSAVEAELDAGSECFIASVASRVYE
CCCCEEEEECCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EKLAALLTAAGCSAVWLKSEAAFDDVTNDYRDPTQLGVDRWMGLVAARARRRAPTLVVSA
HHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
GTAMTVDALSGDGSFLGGLIVPGVALMQRSLQQGTAGGAAAGGAWQAFPRCTADAAYSGI
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHH
IAALCGAVEGQHVRLAAHEGISPACLITGGGAETLLPHLGVDAEHVPTLVLEGIERVARA
HHHHHHHCCCCEEEEEECCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GGRG
CCCC
>Mature Secondary Structure 
SGCRILLDAGNSSLKWAVVEDGTWLARGRSDYSDLSAVEAELDAGSECFIASVASRVYE
CCCEEEEECCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EKLAALLTAAGCSAVWLKSEAAFDDVTNDYRDPTQLGVDRWMGLVAARARRRAPTLVVSA
HHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
GTAMTVDALSGDGSFLGGLIVPGVALMQRSLQQGTAGGAAAGGAWQAFPRCTADAAYSGI
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHH
IAALCGAVEGQHVRLAAHEGISPACLITGGGAETLLPHLGVDAEHVPTLVLEGIERVARA
HHHHHHHCCCCEEEEEECCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GGRG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA