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The map label for this gene is argC

Identifier: 74316473

GI number: 74316473

Start: 472373

End: 473401

Strand: Direct

Name: argC

Synonym: Tbd_0455

Alternate gene names: 74316473

Gene position: 472373-473401 (Clockwise)

Preceding gene: 74316472

Following gene: 74316474

Centisome position: 16.23

GC content: 64.82

Gene sequence:

>1029_bases
ATGATCAAGGTCGGAATTGTGGGCGGCACGGGTTATACGGGCGTCGAGTTGCTGCGACTACTGGCGCGTCACCCCGAGGT
CGAATTGAAGGCGATCACCTCGCGCAAGGAGGCTGGCATGCCGGTCGCCGACATGTTTCCCAATCTTCGCGGCCGGGTGG
GTCTGGCTTTTTCCACACCCGAGGAAGCAGGGCTCGAGACGTGCGACGTCGTGTTCTTCGCCACGCCCAATGGGGTGGCG
ATGCAACAGACGCGTGCGCTGCTCGACGCTGGCGTCAAGGTGATCGATCTGGCCGCCGACTTCCGCATCAAGGACGTCGC
CGAGTGGCAGAAGTGGTACAAGATGGAGCACGCCTGCCCCGACCTGGTCGACGAGGCGGTCTATGGTCTGCCCGAGATCA
ACCGCGACAAGATCAAGGCGGCACGCCTGATCGCCAACCCCGGTTGCTACCCGACTGCGGTGCAGCTCGGGTTTCTGCCG
CTTCTGGAAGCAGGCGTCGCCGAAACCGGTACCCTCATCGCCGACGCCAAGTCCGGCGTGTCGGGGGCGGGCCGCAAGGC
CGAGACCCATATCCTCTTCGCCGAGGCGGCCGACAACTTCAAGGCCTACGCGGTCGGCGGCCACCGTCATTGGCCGGAAA
TCAAGCAGGGGCTGGAGATTTTTGCAGGCGGACCTGTGGGTTTTACCTTCGTGCCGCACCTGACGCCGCTCATCCGCGGT
ATCCACGCCACGCTCTACGCCAGGGTGAGCGCGGACGTCGACCTGCAGGCCTTGTACGAGAAGCGTTACACGGACGAGGC
TTTCGTCGATGTCATGCCGGCCGGTGCCTGCCCGGAGACCCGCTCGGTCCGTGGGGCGAACGTCTGCCGCATCGCCGTGC
ACCGCCAGCAGGGAAGCGACATGGTGATCGTGCTGTCTGTGATCGACAACCTGGTCAAAGGCGCCGCGGGGCAGGCGGTG
CAGAACATGAACATCCTGTTCGGGCTGGCCGAGGATACGGCGCTGTCGGACGTCGGCATGCTCCCCTGA

Upstream 100 bases:

>100_bases
TTCGGCGCCCGAAAAAAGCCGCCCCGAACCGGGCGGCTTTTTTTGTGCCCGGGCGAGCGGCTACCTTACAATTACTCATC
CATCGCAAGGAAGTTTCACC

Downstream 100 bases:

>100_bases
GCGCGGAACTCCGCGGCCCGCTCAGGGTCTTTGCTTGACGCAAGACGGGTGAAGCGGATAATCACCCCACACTTTTTCAA
GGAGCATCACCATGAATGCA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MIKVGIVGGTGYTGVELLRLLARHPEVELKAITSRKEAGMPVADMFPNLRGRVGLAFSTPEEAGLETCDVVFFATPNGVA
MQQTRALLDAGVKVIDLAADFRIKDVAEWQKWYKMEHACPDLVDEAVYGLPEINRDKIKAARLIANPGCYPTAVQLGFLP
LLEAGVAETGTLIADAKSGVSGAGRKAETHILFAEAADNFKAYAVGGHRHWPEIKQGLEIFAGGPVGFTFVPHLTPLIRG
IHATLYARVSADVDLQALYEKRYTDEAFVDVMPAGACPETRSVRGANVCRIAVHRQQGSDMVIVLSVIDNLVKGAAGQAV
QNMNILFGLAEDTALSDVGMLP

Sequences:

>Translated_342_residues
MIKVGIVGGTGYTGVELLRLLARHPEVELKAITSRKEAGMPVADMFPNLRGRVGLAFSTPEEAGLETCDVVFFATPNGVA
MQQTRALLDAGVKVIDLAADFRIKDVAEWQKWYKMEHACPDLVDEAVYGLPEINRDKIKAARLIANPGCYPTAVQLGFLP
LLEAGVAETGTLIADAKSGVSGAGRKAETHILFAEAADNFKAYAVGGHRHWPEIKQGLEIFAGGPVGFTFVPHLTPLIRG
IHATLYARVSADVDLQALYEKRYTDEAFVDVMPAGACPETRSVRGANVCRIAVHRQQGSDMVIVLSVIDNLVKGAAGQAV
QNMNILFGLAEDTALSDVGMLP
>Mature_342_residues
MIKVGIVGGTGYTGVELLRLLARHPEVELKAITSRKEAGMPVADMFPNLRGRVGLAFSTPEEAGLETCDVVFFATPNGVA
MQQTRALLDAGVKVIDLAADFRIKDVAEWQKWYKMEHACPDLVDEAVYGLPEINRDKIKAARLIANPGCYPTAVQLGFLP
LLEAGVAETGTLIADAKSGVSGAGRKAETHILFAEAADNFKAYAVGGHRHWPEIKQGLEIFAGGPVGFTFVPHLTPLIRG
IHATLYARVSADVDLQALYEKRYTDEAFVDVMPAGACPETRSVRGANVCRIAVHRQQGSDMVIVLSVIDNLVKGAAGQAV
QNMNILFGLAEDTALSDVGMLP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=37.5, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320913, Length=340, Percent_Identity=31.1764705882353, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_THIDA (Q3SF19)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314213.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q3SF19
- SMR:   Q3SF19
- STRING:   Q3SF19
- GeneID:   3673083
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0455
- NMPDR:   fig|292415.3.peg.1026
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q3SF19
- ProtClustDB:   PRK00436
- BioCyc:   TDEN292415:TBD_0455-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36694; Mature: 36694

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGIVGGTGYTGVELLRLLARHPEVELKAITSRKEAGMPVADMFPNLRGRVGLAFSTP
CEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHHCCCCCCCEEEEECCC
EEAGLETCDVVFFATPNGVAMQQTRALLDAGVKVIDLAADFRIKDVAEWQKWYKMEHACP
HHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCH
DLVDEAVYGLPEINRDKIKAARLIANPGCYPTAVQLGFLPLLEAGVAETGTLIADAKSGV
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SGAGRKAETHILFAEAADNFKAYAVGGHRHWPEIKQGLEIFAGGPVGFTFVPHLTPLIRG
CCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHCCCEEEECCCCCEEEHHHHHHHHHH
IHATLYARVSADVDLQALYEKRYTDEAFVDVMPAGACPETRSVRGANVCRIAVHRQQGSD
HHHHHEEEECCCCHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCEEEEEEEECCCCC
MVIVLSVIDNLVKGAAGQAVQNMNILFGLAEDTALSDVGMLP
EEEEHHHHHHHHHCCCCHHHHCCEEEEEECCCCHHCCCCCCC
>Mature Secondary Structure
MIKVGIVGGTGYTGVELLRLLARHPEVELKAITSRKEAGMPVADMFPNLRGRVGLAFSTP
CEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHCCCCHHHHCCCCCCCEEEEECCC
EEAGLETCDVVFFATPNGVAMQQTRALLDAGVKVIDLAADFRIKDVAEWQKWYKMEHACP
HHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCH
DLVDEAVYGLPEINRDKIKAARLIANPGCYPTAVQLGFLPLLEAGVAETGTLIADAKSGV
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SGAGRKAETHILFAEAADNFKAYAVGGHRHWPEIKQGLEIFAGGPVGFTFVPHLTPLIRG
CCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHCCCEEEECCCCCEEEHHHHHHHHHH
IHATLYARVSADVDLQALYEKRYTDEAFVDVMPAGACPETRSVRGANVCRIAVHRQQGSD
HHHHHEEEECCCCHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCEEEEEEEECCCCC
MVIVLSVIDNLVKGAAGQAVQNMNILFGLAEDTALSDVGMLP
EEEEHHHHHHHHHCCCCHHHHCCEEEEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA