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The map label for this gene is erpA

Identifier: 74316474

GI number: 74316474

Start: 473493

End: 473843

Strand: Direct

Name: erpA

Synonym: Tbd_0456

Alternate gene names: 74316474

Gene position: 473493-473843 (Clockwise)

Preceding gene: 74316473

Following gene: 74316477

Centisome position: 16.27

GC content: 59.26

Gene sequence:

>351_bases
ATGAATGCAACCACCGAGATGGAATCCCCGCTCGTCTTCACCGACAGCGCCGCAAGCAAAGTCAAAAGCCTGATCGACGA
GGAGGGTAACCCTGACCTCAAGCTGCGCGTGTTCGTGTCGGGCGGCGGCTGCTCGGGCTTTCAGTACGGCTTCACCTTCG
ACGAAGCACAAAACGCCGACGATACCGTTATGGTGAAAAACGGCGTGACCCTGCTCGTCGATTCGATGAGCTTCCAGTAT
CTGGTCGGCGCCGAAATCGACTATTCGGAAGGCCTCGAAGGCGCGCAGTTCGTGATCAAGAACCCGAACGCCACGACCAC
CTGCGGCTGCGGCTCGTCCTTCTCGGCCTGA

Upstream 100 bases:

>100_bases
CTCCCCTGAGCGCGGAACTCCGCGGCCCGCTCAGGGTCTTTGCTTGACGCAAGACGGGTGAAGCGGATAATCACCCCACA
CTTTTTCAAGGAGCATCACC

Downstream 100 bases:

>100_bases
GGCGCTGCGCGCCCGGCAGAAAGCGGCTTCGGCCGCTTTTTTCGTTTCCGGTCCGGCTTCAGGCCGGATGGATCGCGCCG
AGTATGCGTTCCCCGCATGC

Product: HesB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MNATTEMESPLVFTDSAASKVKSLIDEEGNPDLKLRVFVSGGGCSGFQYGFTFDEAQNADDTVMVKNGVTLLVDSMSFQY
LVGAEIDYSEGLEGAQFVIKNPNATTTCGCGSSFSA

Sequences:

>Translated_116_residues
MNATTEMESPLVFTDSAASKVKSLIDEEGNPDLKLRVFVSGGGCSGFQYGFTFDEAQNADDTVMVKNGVTLLVDSMSFQY
LVGAEIDYSEGLEGAQFVIKNPNATTTCGCGSSFSA
>Mature_116_residues
MNATTEMESPLVFTDSAASKVKSLIDEEGNPDLKLRVFVSGGGCSGFQYGFTFDEAQNADDTVMVKNGVTLLVDSMSFQY
LVGAEIDYSEGLEGAQFVIKNPNATTTCGCGSSFSA

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=109, Percent_Identity=42.2018348623853, Blast_Score=82, Evalue=8e-17,
Organism=Homo sapiens, GI52426768, Length=108, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=66.9811320754717, Blast_Score=156, Evalue=3e-40,
Organism=Escherichia coli, GI1788877, Length=108, Percent_Identity=37.962962962963, Blast_Score=67, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=111, Percent_Identity=39.6396396396396, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=111, Percent_Identity=28.8288288288288, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146411, Length=110, Percent_Identity=28.1818181818182, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=32.3809523809524, Blast_Score=68, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24649697, Length=82, Percent_Identity=46.3414634146341, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24642263, Length=109, Percent_Identity=33.9449541284404, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_THIDA (Q3SF18)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314214.1
- HSSP:   O67709
- ProteinModelPortal:   Q3SF18
- SMR:   Q3SF18
- STRING:   Q3SF18
- GeneID:   3673084
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0456
- NMPDR:   fig|292415.3.peg.1027
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   Q3SF18
- BioCyc:   TDEN292415:TBD_0456-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12274; Mature: 12274

Theoretical pI: Translated: 3.82; Mature: 3.82

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATTEMESPLVFTDSAASKVKSLIDEEGNPDLKLRVFVSGGGCSGFQYGFTFDEAQNAD
CCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCC
DTVMVKNGVTLLVDSMSFQYLVGAEIDYSEGLEGAQFVIKNPNATTTCGCGSSFSA
CEEEEECCEEEEEECCCEEEEECCCCCHHCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure
MNATTEMESPLVFTDSAASKVKSLIDEEGNPDLKLRVFVSGGGCSGFQYGFTFDEAQNAD
CCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCC
DTVMVKNGVTLLVDSMSFQYLVGAEIDYSEGLEGAQFVIKNPNATTTCGCGSSFSA
CEEEEECCEEEEEECCCEEEEECCCCCHHCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA