Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 74316408

GI number: 74316408

Start: 417818

End: 418909

Strand: Direct

Name: engD [H]

Synonym: Tbd_0390

Alternate gene names: 74316408

Gene position: 417818-418909 (Clockwise)

Preceding gene: 74316407

Following gene: 74316409

Centisome position: 14.36

GC content: 66.12

Gene sequence:

>1092_bases
ATGAGCCTCAAATGCGGCATCGTTGGCTTGCCCAACGTCGGAAAATCCACCCTGTTCAACGCGCTGACCCAGGCGGGCAT
CGCGGCGGAAAACTACCCGTTCTGCACCATCGAGCCGAACACGGGCGTCGTCGAGGTGCCGGACCCGCGGCTCGACGAGC
TCGCGAAGGTCGTCAAGCCGCAGCGCGTCGTTCCTGCGATCGTCGAGTTCGTCGACATCGCGGGCCTGGTCGCCGGGGCA
TCGAAGGGCGAGGGCCTCGGCAACCAGTTTCTCGCCAACATTCGGGAGACCGACGCGATCTGCCACGTCGTGCGCTGTTT
CCATGACGAAAACGTGATCCACGTCGCCGGCAAGGTCGACCCGCTGTCCGACGTCGAGACGATCGCGACCGAACTCGCGC
TCGCCGATCTCGCGAGCGCCGAAAAAGCACTGGCCCGTTACGAGAAACCCGCCCGTGCCGGAGACAAGGAGGCGCAGCAC
ATGGTCGCGGCGCTGAAACCGGTCGTCGCGGCGCTAAACGAGGGTCGCCCGGCGCGCGCCGCCGGCCTCGACGCCGAAGG
GCTCGCGCGCATCAAGCCGCTGTGCCTGATGACCGTCAAGCCGACGCTCTATGTCGCCAACGTCGACGAGGACGGCTTCC
ACGACAATCCGCTGCTCGACGCCCTGACTGCCTTTGCGGAAAAAGAGGGCGCCCCGGTGGTGCCGGTCTGTGCCGCGCTC
GAAGCCGAACTGCAGGAGCTTTCGCCGGAGGAGCGCGTGGAATACCTGAACGAGCTCGGCTGGGACGAGCCCGGTCTCAA
TCGCCTGATACGCGCGGCCTACGCGCTGCTCGGTCTGCAGACCTATTTCACGGCCGGCGTGAAGGAGGTGCGGGCGTGGA
CGATCCACAAGGGCGACACCGCACCGCAGGCGGCCGGCGTCATCCACACCGACTTCGAGCGGGGCTTCATCCGCGCGCAG
ACCATTTCCTTCGACGACTTCATCGCCTGCCAGGGCGAGCAGGGCGCGAAGGAGGCCGGCAAGATGCGCGCCGAGGGCAA
GGAATACGTCGTCAAGGACGGCGACGTGCTCAATTTCCTGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
GTGCGCTCGGACTCCTTCCCCTGATCGAAAAGGGCGAGTGGAACGCCGCGACCCAGCGCGCCAACAGCAAACCTGCATCA
CCCAAATCCCAGGAAACCCC

Downstream 100 bases:

>100_bases
AATCGCGAGTTTTTGCCGGCGAGTGTTTGACAGCATCTTCCCGGCACACATATAATCTCGCGCTTCGTTTGGGTGGGGTT
CCCGAGCGGTCAAAGGGATC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLKCGIVGLPNVGKSTLFNALTQAGIAAENYPFCTIEPNTGVVEVPDPRLDELAKVVKPQRVVPAIVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAICHVVRCFHDENVIHVAGKVDPLSDVETIATELALADLASAEKALARYEKPARAGDKEAQH
MVAALKPVVAALNEGRPARAAGLDAEGLARIKPLCLMTVKPTLYVANVDEDGFHDNPLLDALTAFAEKEGAPVVPVCAAL
EAELQELSPEERVEYLNELGWDEPGLNRLIRAAYALLGLQTYFTAGVKEVRAWTIHKGDTAPQAAGVIHTDFERGFIRAQ
TISFDDFIACQGEQGAKEAGKMRAEGKEYVVKDGDVLNFLFNV

Sequences:

>Translated_363_residues
MSLKCGIVGLPNVGKSTLFNALTQAGIAAENYPFCTIEPNTGVVEVPDPRLDELAKVVKPQRVVPAIVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAICHVVRCFHDENVIHVAGKVDPLSDVETIATELALADLASAEKALARYEKPARAGDKEAQH
MVAALKPVVAALNEGRPARAAGLDAEGLARIKPLCLMTVKPTLYVANVDEDGFHDNPLLDALTAFAEKEGAPVVPVCAAL
EAELQELSPEERVEYLNELGWDEPGLNRLIRAAYALLGLQTYFTAGVKEVRAWTIHKGDTAPQAAGVIHTDFERGFIRAQ
TISFDDFIACQGEQGAKEAGKMRAEGKEYVVKDGDVLNFLFNV
>Mature_362_residues
SLKCGIVGLPNVGKSTLFNALTQAGIAAENYPFCTIEPNTGVVEVPDPRLDELAKVVKPQRVVPAIVEFVDIAGLVAGAS
KGEGLGNQFLANIRETDAICHVVRCFHDENVIHVAGKVDPLSDVETIATELALADLASAEKALARYEKPARAGDKEAQHM
VAALKPVVAALNEGRPARAAGLDAEGLARIKPLCLMTVKPTLYVANVDEDGFHDNPLLDALTAFAEKEGAPVVPVCAALE
AELQELSPEERVEYLNELGWDEPGLNRLIRAAYALLGLQTYFTAGVKEVRAWTIHKGDTAPQAAGVIHTDFERGFIRAQT
ISFDDFIACQGEQGAKEAGKMRAEGKEYVVKDGDVLNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=44.7154471544715, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI58761502, Length=220, Percent_Identity=39.5454545454545, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=68.5950413223141, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1789574, Length=141, Percent_Identity=31.2056737588652, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.3497267759563, Blast_Score=285, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=40.3794037940379, Blast_Score=253, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=34.2036553524804, Blast_Score=192, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6321649, Length=229, Percent_Identity=33.6244541484716, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=44.6866485013624, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=44.6866485013624, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=44.6866485013624, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=42.0731707317073, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24585318, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38939; Mature: 38808

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKCGIVGLPNVGKSTLFNALTQAGIAAENYPFCTIEPNTGVVEVPDPRLDELAKVVKP
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHCC
QRVVPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAICHVVRCFHDENVIHVAGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PLSDVETIATELALADLASAEKALARYEKPARAGDKEAQHMVAALKPVVAALNEGRPARA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
AGLDAEGLARIKPLCLMTVKPTLYVANVDEDGFHDNPLLDALTAFAEKEGAPVVPVCAAL
CCCCHHHHHHHCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
EAELQELSPEERVEYLNELGWDEPGLNRLIRAAYALLGLQTYFTAGVKEVRAWTIHKGDT
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
APQAAGVIHTDFERGFIRAQTISFDDFIACQGEQGAKEAGKMRAEGKEYVVKDGDVLNFL
CCHHCCCEEECCCCCEEEEEEECCCHHEEECCCCCHHHHHHHHCCCCEEEECCCHHHHHH
FNV
HCC
>Mature Secondary Structure 
SLKCGIVGLPNVGKSTLFNALTQAGIAAENYPFCTIEPNTGVVEVPDPRLDELAKVVKP
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCHHHHHHHHCC
QRVVPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAICHVVRCFHDENVIHVAGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PLSDVETIATELALADLASAEKALARYEKPARAGDKEAQHMVAALKPVVAALNEGRPARA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHH
AGLDAEGLARIKPLCLMTVKPTLYVANVDEDGFHDNPLLDALTAFAEKEGAPVVPVCAAL
CCCCHHHHHHHCCEEEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
EAELQELSPEERVEYLNELGWDEPGLNRLIRAAYALLGLQTYFTAGVKEVRAWTIHKGDT
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
APQAAGVIHTDFERGFIRAQTISFDDFIACQGEQGAKEAGKMRAEGKEYVVKDGDVLNFL
CCHHCCCEEECCCCCEEEEEEECCCHHEEECCCCCHHHHHHHHCCCCEEEECCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]