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The map label for this gene is dacC [H]

Identifier: 74316284

GI number: 74316284

Start: 287620

End: 288753

Strand: Direct

Name: dacC [H]

Synonym: Tbd_0266

Alternate gene names: 74316284

Gene position: 287620-288753 (Clockwise)

Preceding gene: 74316283

Following gene: 74316285

Centisome position: 9.88

GC content: 68.34

Gene sequence:

>1134_bases
ATGATTTTGAAGCCCCCGATGAAATTCCTGTGGTTGACGCTCGCCTGGCTGCTATCCGCTTCGGCAATCGCCGCGCCGAC
CGGTATTGCGGCCCGCGCGTGGGTCATCGTCGATCAGACGAGCGGGCGAGAACTCGCCTCGCATCAGCCCGACCTGCCGC
TCGCGCCCGCGTCGCTGACGCAGTTGATGACGGTCTACGTCTTGCTGGGTGACATCCGCCGCAACGCGCTGCGTCTCGAC
GCGGAAGTCCGCGTCCCGGACGCCGCCGCCGAGGCCGACGGCGCGCGCGTGTTTCTCAAGCCCGGCGAGCGCGTGCGCGT
CGACACGTTGCTGCGCGCGATACTCGTGCAGTCGGCGAGCGATGCGACCGTGACGCTGGCGACGGCGACCGACGGCAGCG
AGGCCGCGTTCGTCGAGCGCATGAATCGCGAAGCTGCGCGGCTCGGCATGAAGCGCACGCACTTTGCCAACGCCACGGGT
CTCGCCCAGCCGGGGCACGTTTCCAGCGCGCGCGACCTTGCTGTGCTCGGACGCGCACTGCTCCGCGAGCATCCCGCGCA
GCAGGCCTTGTTTGCGCAGAAAGAGTTCACGCTAGACGGCCTGACCTACTACAACGCCAACCGCCTGCTCTGGCGCGACG
GCACCGTGACCGGGCTGAAAGTCGGCCGCAATCCCGAGTCCGGCTATTCGGCCGTGGCGTCGGCGCAGCGGGGCGAGCAG
CGCCGCGTCGCCGTCGTGCTCGGCGCGCGCTCGGATGCCCAGCGCACGCAGGACGCGCTGCGCCTGCTCAACTACGGCTT
CGAGAAATTCGATAGCGTGCTGCTTTATCGTGCGCGCCAGCCGGTCAAGGTGGTCCGGCTCTATCGCGGCACCCGCCAGT
CGGTGGGCATCGGTTTCGAACAGGATTTCCATCTGCTCGCACCGCGTGGCAGCCTGCCGCGCGTGAAGGCCGAGATCGTG
ACCCAGCGCCCGATCGTCGCACCGATCCACAAGGGCCAGCGCATCGGACTGCTGCGCCTGACGCTTGACGGCAAGCCGCT
CGGCAACCGTCCGCTGGTCGCACTGCACGACGTCGCCGTTGCCGGCATCTTCGGGCGCGGCTGGGATTCGCTGCGTCTGC
TCTTCGACCAATGA

Upstream 100 bases:

>100_bases
ATGTGCAACTCGGGCCTTATCCGAGCGACGCCGCCGCGAAGGCCGACCGCGCGCGGGTTAGGGAACGTCTCGACCTTTCG
GCAGTCCTCGTCAGACGCGA

Downstream 100 bases:

>100_bases
GCGTCTATCTAAACGGCCGCTTCCAGCCGCTGGCCGAGGCGACGATCCCCGTGCTCGACCGCGGCTTCGTTTTCGGCGAC
GGTGTCTACGAACTGGTGCC

Product: serine-type D-ala-D-ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MILKPPMKFLWLTLAWLLSASAIAAPTGIAARAWVIVDQTSGRELASHQPDLPLAPASLTQLMTVYVLLGDIRRNALRLD
AEVRVPDAAAEADGARVFLKPGERVRVDTLLRAILVQSASDATVTLATATDGSEAAFVERMNREAARLGMKRTHFANATG
LAQPGHVSSARDLAVLGRALLREHPAQQALFAQKEFTLDGLTYYNANRLLWRDGTVTGLKVGRNPESGYSAVASAQRGEQ
RRVAVVLGARSDAQRTQDALRLLNYGFEKFDSVLLYRARQPVKVVRLYRGTRQSVGIGFEQDFHLLAPRGSLPRVKAEIV
TQRPIVAPIHKGQRIGLLRLTLDGKPLGNRPLVALHDVAVAGIFGRGWDSLRLLFDQ

Sequences:

>Translated_377_residues
MILKPPMKFLWLTLAWLLSASAIAAPTGIAARAWVIVDQTSGRELASHQPDLPLAPASLTQLMTVYVLLGDIRRNALRLD
AEVRVPDAAAEADGARVFLKPGERVRVDTLLRAILVQSASDATVTLATATDGSEAAFVERMNREAARLGMKRTHFANATG
LAQPGHVSSARDLAVLGRALLREHPAQQALFAQKEFTLDGLTYYNANRLLWRDGTVTGLKVGRNPESGYSAVASAQRGEQ
RRVAVVLGARSDAQRTQDALRLLNYGFEKFDSVLLYRARQPVKVVRLYRGTRQSVGIGFEQDFHLLAPRGSLPRVKAEIV
TQRPIVAPIHKGQRIGLLRLTLDGKPLGNRPLVALHDVAVAGIFGRGWDSLRLLFDQ
>Mature_377_residues
MILKPPMKFLWLTLAWLLSASAIAAPTGIAARAWVIVDQTSGRELASHQPDLPLAPASLTQLMTVYVLLGDIRRNALRLD
AEVRVPDAAAEADGARVFLKPGERVRVDTLLRAILVQSASDATVTLATATDGSEAAFVERMNREAARLGMKRTHFANATG
LAQPGHVSSARDLAVLGRALLREHPAQQALFAQKEFTLDGLTYYNANRLLWRDGTVTGLKVGRNPESGYSAVASAQRGEQ
RRVAVVLGARSDAQRTQDALRLLNYGFEKFDSVLLYRARQPVKVVRLYRGTRQSVGIGFEQDFHLLAPRGSLPRVKAEIV
TQRPIVAPIHKGQRIGLLRLTLDGKPLGNRPLVALHDVAVAGIFGRGWDSLRLLFDQ

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=363, Percent_Identity=37.465564738292, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1786851, Length=355, Percent_Identity=34.9295774647887, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI87082022, Length=349, Percent_Identity=36.3896848137536, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI87082054, Length=247, Percent_Identity=32.7935222672065, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41236; Mature: 41236

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKPPMKFLWLTLAWLLSASAIAAPTGIAARAWVIVDQTSGRELASHQPDLPLAPASLT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCHHHHH
QLMTVYVLLGDIRRNALRLDAEVRVPDAAAEADGARVFLKPGERVRVDTLLRAILVQSAS
HHHHHHHHHHHHHHHHEEECCEEECCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHCCCC
DATVTLATATDGSEAAFVERMNREAARLGMKRTHFANATGLAQPGHVSSARDLAVLGRAL
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LREHPAQQALFAQKEFTLDGLTYYNANRLLWRDGTVTGLKVGRNPESGYSAVASAQRGEQ
HHHCCHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCC
RRVAVVLGARSDAQRTQDALRLLNYGFEKFDSVLLYRARQPVKVVRLYRGTRQSVGIGFE
CEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCCCCC
QDFHLLAPRGSLPRVKAEIVTQRPIVAPIHKGQRIGLLRLTLDGKPLGNRPLVALHDVAV
CCCEEECCCCCCCCHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCCCCCCEEEEEHHHH
AGIFGRGWDSLRLLFDQ
HHHHCCCCCCEEEEECC
>Mature Secondary Structure
MILKPPMKFLWLTLAWLLSASAIAAPTGIAARAWVIVDQTSGRELASHQPDLPLAPASLT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCHHHHH
QLMTVYVLLGDIRRNALRLDAEVRVPDAAAEADGARVFLKPGERVRVDTLLRAILVQSAS
HHHHHHHHHHHHHHHHEEECCEEECCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHCCCC
DATVTLATATDGSEAAFVERMNREAARLGMKRTHFANATGLAQPGHVSSARDLAVLGRAL
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LREHPAQQALFAQKEFTLDGLTYYNANRLLWRDGTVTGLKVGRNPESGYSAVASAQRGEQ
HHHCCHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCC
RRVAVVLGARSDAQRTQDALRLLNYGFEKFDSVLLYRARQPVKVVRLYRGTRQSVGIGFE
CEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCCCCC
QDFHLLAPRGSLPRVKAEIVTQRPIVAPIHKGQRIGLLRLTLDGKPLGNRPLVALHDVAV
CCCEEECCCCCCCCHHHHHHHCCCCEEECCCCCEEEEEEEEECCCCCCCCCEEEEEHHHH
AGIFGRGWDSLRLLFDQ
HHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]