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The map label for this gene is mreB [H]

Identifier: 74316278

GI number: 74316278

Start: 281252

End: 282295

Strand: Direct

Name: mreB [H]

Synonym: Tbd_0260

Alternate gene names: 74316278

Gene position: 281252-282295 (Clockwise)

Preceding gene: 74316274

Following gene: 74316279

Centisome position: 9.67

GC content: 66.57

Gene sequence:

>1044_bases
ATGTTCAAGTTCTTGACCAGCTATTTCTCGACCGATCTCGCGATCGACCTCGGTACCGCCAACACGCTGATCTACGTGCG
TGATCGTGGCATCGTCCTCGACGAGCCGTCGGTGGTGTCGATCCGCACCGACGCGTCGGTCGGCGGCAAGCGCACGGTCC
AGGCGGTCGGTGCCGAGGCCAAGCAGATGCTCGGACGCACGCCGGGCAACCTGCAGGCGATCCGGCCGATGAAGGACGGC
GTGATCGCCGACTTCACCGTCACCGAGCAGATGCTCAAGTATTTCATCAAGAAGGTGCACGACACGCGCATGCTGCGGCC
GAGCCCGCGCATCATCATCTGCGTGCCCTGCGGCTCGACCCAGGTCGAGCGGCGCGCGATCCGCGAGTCGGCGATCGGCG
CCGGCGCCCGCCAGGTCTATCTGATCGAGGAACCGATGGCGGCGGCGATCGGCGCCGGCATGCCGGTGGCGGACGCGACC
GGGTCGATGGTCGTCGACATCGGCGGCGGCACCACCGAGGTCGGCGTGATCTCGCTCGGCGGCGTCGTCTACGCCAACTC
GGTACGCGTCGGCGGCGACCGCATGGACGACGCGATCATCAATTACATTCGCCGCAACTACGGCATGCTGATCGGCGAGG
CGACGGCCGAACTGATCAAGAAGAAAATGGGCTCGGCCTTCCCTGGCGCCGAAGTGCTCGAAATGGAAGTCAAGGGCCGC
AGCCTCGCCGAAGGGGTGCCGCGCAGCTTCAACGTCTCGTCGAACGAAATCCTCGAAGCCCTGACCGAACCGCTCAACGC
GATCGTCAGCGCGGTCAAGCTCGCGCTCGAGCAGACGCCGCCCGAACTCGGCGCCGACATCGCCGAGAAGGGCATGGTGC
TGACCGGCGGCGGTGCGCTGCTGCGCGATCTCGACCGCCTGCTGATGGAAGAGACCGGTCTGCCCGTCATCGTCGCGGAC
GACCCGCTGACGTGCGTGGTGCGCGGGTCGGGCCGCGCGCTCGAGGAAATGGACAAGCTCGCGTCGGTGTTCACCAACGA
GTGA

Upstream 100 bases:

>100_bases
GAGGCACCTAGATGACTTACGGGAACGAAGCCCGTTAGGGTATCATAGCCCCCTTGTTTTTTCTGCCCTTTTATCCGTTC
GAACCGGGATCGCAGCCACT

Downstream 100 bases:

>100_bases
AGAAGCGCGCCGCTGCTGACCGGGTCGGCTGATGGCGATGCCGGGCCAGCTCATGTTCGCGCGCCGGCTCGGGCCGACGG
CGCGCCTGTCGATCTGGCTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFKFLTSYFSTDLAIDLGTANTLIYVRDRGIVLDEPSVVSIRTDASVGGKRTVQAVGAEAKQMLGRTPGNLQAIRPMKDG
VIADFTVTEQMLKYFIKKVHDTRMLRPSPRIIICVPCGSTQVERRAIRESAIGAGARQVYLIEEPMAAAIGAGMPVADAT
GSMVVDIGGGTTEVGVISLGGVVYANSVRVGGDRMDDAIINYIRRNYGMLIGEATAELIKKKMGSAFPGAEVLEMEVKGR
SLAEGVPRSFNVSSNEILEALTEPLNAIVSAVKLALEQTPPELGADIAEKGMVLTGGGALLRDLDRLLMEETGLPVIVAD
DPLTCVVRGSGRALEEMDKLASVFTNE

Sequences:

>Translated_347_residues
MFKFLTSYFSTDLAIDLGTANTLIYVRDRGIVLDEPSVVSIRTDASVGGKRTVQAVGAEAKQMLGRTPGNLQAIRPMKDG
VIADFTVTEQMLKYFIKKVHDTRMLRPSPRIIICVPCGSTQVERRAIRESAIGAGARQVYLIEEPMAAAIGAGMPVADAT
GSMVVDIGGGTTEVGVISLGGVVYANSVRVGGDRMDDAIINYIRRNYGMLIGEATAELIKKKMGSAFPGAEVLEMEVKGR
SLAEGVPRSFNVSSNEILEALTEPLNAIVSAVKLALEQTPPELGADIAEKGMVLTGGGALLRDLDRLLMEETGLPVIVAD
DPLTCVVRGSGRALEEMDKLASVFTNE
>Mature_347_residues
MFKFLTSYFSTDLAIDLGTANTLIYVRDRGIVLDEPSVVSIRTDASVGGKRTVQAVGAEAKQMLGRTPGNLQAIRPMKDG
VIADFTVTEQMLKYFIKKVHDTRMLRPSPRIIICVPCGSTQVERRAIRESAIGAGARQVYLIEEPMAAAIGAGMPVADAT
GSMVVDIGGGTTEVGVISLGGVVYANSVRVGGDRMDDAIINYIRRNYGMLIGEATAELIKKKMGSAFPGAEVLEMEVKGR
SLAEGVPRSFNVSSNEILEALTEPLNAIVSAVKLALEQTPPELGADIAEKGMVLTGGGALLRDLDRLLMEETGLPVIVAD
DPLTCVVRGSGRALEEMDKLASVFTNE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=338, Percent_Identity=73.6686390532544, Blast_Score=511, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36961; Mature: 36961

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFLTSYFSTDLAIDLGTANTLIYVRDRGIVLDEPSVVSIRTDASVGGKRTVQAVGAEA
CHHHHHHHHCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCHHHHHHHHHH
KQMLGRTPGNLQAIRPMKDGVIADFTVTEQMLKYFIKKVHDTRMLRPSPRIIICVPCGST
HHHHCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCH
QVERRAIRESAIGAGARQVYLIEEPMAAAIGAGMPVADATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GVVYANSVRVGGDRMDDAIINYIRRNYGMLIGEATAELIKKKMGSAFPGAEVLEMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCC
SLAEGVPRSFNVSSNEILEALTEPLNAIVSAVKLALEQTPPELGADIAEKGMVLTGGGAL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCEEEECCCHH
LRDLDRLLMEETGLPVIVADDPLTCVVRGSGRALEEMDKLASVFTNE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKFLTSYFSTDLAIDLGTANTLIYVRDRGIVLDEPSVVSIRTDASVGGKRTVQAVGAEA
CHHHHHHHHCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCHHHHHHHHHH
KQMLGRTPGNLQAIRPMKDGVIADFTVTEQMLKYFIKKVHDTRMLRPSPRIIICVPCGST
HHHHCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCH
QVERRAIRESAIGAGARQVYLIEEPMAAAIGAGMPVADATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GVVYANSVRVGGDRMDDAIINYIRRNYGMLIGEATAELIKKKMGSAFPGAEVLEMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCC
SLAEGVPRSFNVSSNEILEALTEPLNAIVSAVKLALEQTPPELGADIAEKGMVLTGGGAL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCEEEECCCHH
LRDLDRLLMEETGLPVIVADDPLTCVVRGSGRALEEMDKLASVFTNE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]