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The map label for this gene is metA [H]

Identifier: 74316264

GI number: 74316264

Start: 268846

End: 269895

Strand: Direct

Name: metA [H]

Synonym: Tbd_0246

Alternate gene names: 74316264

Gene position: 268846-269895 (Clockwise)

Preceding gene: 74316263

Following gene: 74316265

Centisome position: 9.24

GC content: 67.62

Gene sequence:

>1050_bases
GTGCCGCTCGTCGCGCACAACGCCCTGCCGACCTTCGAGCGCCTGCGCCGCGACGGCATCACGGTGCTGTCGACCGAGCG
CGCCGCCAACCAGGAAATCCGCGAATTGCACGTCGGCCTGCTGAACATGATGCCCGACGCCGCGCTCGAAGCGACCGAGC
GGCAGTTCTATCGGCTGGTCGGCGAATCGAACCCGATCGCGCAGTTCTACATGCACCCGTTCACGCTCGAGACGCTGCCG
CGCGGCGACAAGGCGCGTGCGCATATCGGGCGCCATTACGAAAAATTCGAGGACATCCGCGCCGCCGGCCTCGACGCGCT
GATCATCACCGGCGCCAACGTCAGCCACGCCAACCTTGCCGACGAGGCCTTCTGGCAGCCGCTCATCGAGGTCATCGACT
GGGCGTGGGACAACGTCACCTCGACGCTGTGCTCGTGCCTCGCGACGCACGCGGTCATGCAGTTCCGCTACGCGCAGACC
CGCGTGCTGCAGCCGCGCAAGATCTGGGGAGTGTTCGAGCATCGCGTGACCGACGTCCGCCACCCGCTCGTCGCCGACGT
CAACACCCGCTTCGACGTGCCGCACTCACGCTGGAACGACGTCTCGCGCGCACAGTTCGAGGCCGCCGGCGTCAAGGTGC
TGGTCGAGAGCGAAGAGGCGGGCGTCCACCTCGCCGTCAGCGGCGACGGGCTGCGCACGGTGTTCTTCCAGGGGCACCCC
GAGTACGACACCGTGTCACTGCTGAAGGAATACAAGCGTGACCTGCTGCTCGCCACGACGGGCGCGCTTGCCGAGCCGCC
CTTCCCGCGCCGTTATTTCGATCGCAAGGCGCAGGCGTTTCTGGCCGAATTCGCGCGCCGCACGCGTGTCGGCGAGACGC
TCGTCTTCCCCGAAGCGGAGGTCGTTCCGCTGCTCGACAATACCTGGCACGACACGGCCGAAGCGGTGATCGGCAACTGG
ATCGGCTGCGTCTATCAGGTCACCCATCGCGAACGCGGCCTGCCCTTCATGCCCGGCGTCGACCCCGACAACCCGCTGGG
CCTCGCGTGA

Upstream 100 bases:

>100_bases
ACGGCTACACGGTGACGTCCGAAGAGGCCGCACAGGTGCGTGACGAGCGCGATTTCCTCGCGCTGCTCGAAGCCGCGATC
GCGCGCAAGGGGAGCTGACC

Downstream 100 bases:

>100_bases
CCGAGGCCCACGCGCACTTCGACGAAGCGGAGGGCGCCCTCGTCGCCCGCGGCGCCTGGCACGCGGACGCCGCGGCGGCG
CTTCCCGACCTTTCCGGCAA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPLVAHNALPTFERLRRDGITVLSTERAANQEIRELHVGLLNMMPDAALEATERQFYRLVGESNPIAQFYMHPFTLETLP
RGDKARAHIGRHYEKFEDIRAAGLDALIITGANVSHANLADEAFWQPLIEVIDWAWDNVTSTLCSCLATHAVMQFRYAQT
RVLQPRKIWGVFEHRVTDVRHPLVADVNTRFDVPHSRWNDVSRAQFEAAGVKVLVESEEAGVHLAVSGDGLRTVFFQGHP
EYDTVSLLKEYKRDLLLATTGALAEPPFPRRYFDRKAQAFLAEFARRTRVGETLVFPEAEVVPLLDNTWHDTAEAVIGNW
IGCVYQVTHRERGLPFMPGVDPDNPLGLA

Sequences:

>Translated_349_residues
MPLVAHNALPTFERLRRDGITVLSTERAANQEIRELHVGLLNMMPDAALEATERQFYRLVGESNPIAQFYMHPFTLETLP
RGDKARAHIGRHYEKFEDIRAAGLDALIITGANVSHANLADEAFWQPLIEVIDWAWDNVTSTLCSCLATHAVMQFRYAQT
RVLQPRKIWGVFEHRVTDVRHPLVADVNTRFDVPHSRWNDVSRAQFEAAGVKVLVESEEAGVHLAVSGDGLRTVFFQGHP
EYDTVSLLKEYKRDLLLATTGALAEPPFPRRYFDRKAQAFLAEFARRTRVGETLVFPEAEVVPLLDNTWHDTAEAVIGNW
IGCVYQVTHRERGLPFMPGVDPDNPLGLA
>Mature_348_residues
PLVAHNALPTFERLRRDGITVLSTERAANQEIRELHVGLLNMMPDAALEATERQFYRLVGESNPIAQFYMHPFTLETLPR
GDKARAHIGRHYEKFEDIRAAGLDALIITGANVSHANLADEAFWQPLIEVIDWAWDNVTSTLCSCLATHAVMQFRYAQTR
VLQPRKIWGVFEHRVTDVRHPLVADVNTRFDVPHSRWNDVSRAQFEAAGVKVLVESEEAGVHLAVSGDGLRTVFFQGHPE
YDTVSLLKEYKRDLLLATTGALAEPPFPRRYFDRKAQAFLAEFARRTRVGETLVFPEAEVVPLLDNTWHDTAEAVIGNWI
GCVYQVTHRERGLPFMPGVDPDNPLGLA

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=274, Percent_Identity=33.9416058394161, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 39428; Mature: 39297

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVAHNALPTFERLRRDGITVLSTERAANQEIRELHVGLLNMMPDAALEATERQFYRLV
CCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GESNPIAQFYMHPFTLETLPRGDKARAHIGRHYEKFEDIRAAGLDALIITGANVSHANLA
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
DEAFWQPLIEVIDWAWDNVTSTLCSCLATHAVMQFRYAQTRVLQPRKIWGVFEHRVTDVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
HPLVADVNTRFDVPHSRWNDVSRAQFEAAGVKVLVESEEAGVHLAVSGDGLRTVFFQGHP
CCCEECCCCCCCCCCHHHCCHHHHHHHHCCEEEEEECCCCCEEEEEECCCEEEEEECCCC
EYDTVSLLKEYKRDLLLATTGALAEPPFPRRYFDRKAQAFLAEFARRTRVGETLVFPEAE
CHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
VVPLLDNTWHDTAEAVIGNWIGCVYQVTHRERGLPFMPGVDPDNPLGLA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLVAHNALPTFERLRRDGITVLSTERAANQEIRELHVGLLNMMPDAALEATERQFYRLV
CCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GESNPIAQFYMHPFTLETLPRGDKARAHIGRHYEKFEDIRAAGLDALIITGANVSHANLA
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
DEAFWQPLIEVIDWAWDNVTSTLCSCLATHAVMQFRYAQTRVLQPRKIWGVFEHRVTDVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
HPLVADVNTRFDVPHSRWNDVSRAQFEAAGVKVLVESEEAGVHLAVSGDGLRTVFFQGHP
CCCEECCCCCCCCCCHHHCCHHHHHHHHCCEEEEEECCCCCEEEEEECCCEEEEEECCCC
EYDTVSLLKEYKRDLLLATTGALAEPPFPRRYFDRKAQAFLAEFARRTRVGETLVFPEAE
CHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
VVPLLDNTWHDTAEAVIGNWIGCVYQVTHRERGLPFMPGVDPDNPLGLA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA