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The map label for this gene is cbbG [H]

Identifier: 74316178

GI number: 74316178

Start: 172476

End: 173477

Strand: Direct

Name: cbbG [H]

Synonym: Tbd_0160

Alternate gene names: 74316178

Gene position: 172476-173477 (Clockwise)

Preceding gene: 74316177

Following gene: 74316179

Centisome position: 5.93

GC content: 62.97

Gene sequence:

>1002_bases
GTGGCTATCAAAGTAGGTATCAACGGTTTTGGCCGCATCGGCCGCATGGCTTTCCGCGCGATCGCCAAGGACTTCCCGGA
CATCGAAGTGGTCGCGATCAACGACCTGCTCGATCCCGAGTACCTGGCCTACATGCTGAAATACGATTCGGTGCACGGCA
ACTTCAAGGGCGACATCGCCGTCGAAGGCAACAACCTCATCGTCAACGGCAAGAAGATCCGCCTGACCGCCGAGCGCGAG
CCCGCCAACCTGAAGTGGAACGAAGTCGGCGCCGAGCTGGTGATCGAGTGCACGGGCTTCTTCCTGACCAAGGAAACCTG
CCAGAAGCACATCGACGCCGGCGCCAAGAAAGTCGTGCAGTCCGCGCCTTCCAAGGACGACACCCCGATGTTCGTATACG
GCGTGAACCACGAGAAGTACGCCGGCGAGGCCATCGTCTCGGCCGCTTCGTGCACGACCAACTGCCTCGCGCCGATCGCC
AAGGTGCTGAACGACAACTGGGGCATCAAGCGCGGCCTGATGAGCACCGTGCACGCCGCCACCGCGACCCAGAAGACCGT
CGACGGCCCGTCGTCCAAGGACTGGCGCGGCGGCCGCGGCATCCTCGAAAACATCATCCCGTCCTCGACCGGCGCCGCCA
AGGCCGTCGGCGTGGTGTTGCCTGAGCTGAAGGGCAAGCTGACCGGCATGGCGTTCCGCGTTCCGACCTCCGACGTCTCG
GTCGTCGACCTGACCGTCGAGCTCGAGAAGCCCGCCAAGTACGCGGACATCTGCGCCGCGATGAAGAAGGCTTCGCAGTC
GGGCGACATCAGCAAGACCCTCGGCTACACCGACGAGAAAGTCGTTTCGACCGACTTCCGCGGCAACGGCTTCTCGTCGA
TCTTCGACGCCGAAGCCGGCATCGCGCTCGACGACACCTTCGTCAAGGTCGTGTCGTGGTACGACAACGAGTACGGCTAC
ACCTGCAACATGCTGCGCTTCGTGCAGCACGTCGCGAAGTAA

Upstream 100 bases:

>100_bases
GCGTCAGAGACGACGCGGCCTTCGGCCGCTCACTCCCTGACCCCTGAATCCCGGCCCCTGACCCCTAGATAAGATTTTCA
ACCTGACTGGGAGACTGTAA

Downstream 100 bases:

>100_bases
GGGGTCAGGATTCAGGGATCAGGGTTCAGGGAATGCGCGGGCGTAGCCCGCCCAAATCAGGGGTGCGGCCTCGGCCGCTC
GTTCCCTGACCCCTGAATCC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAIKVGINGFGRIGRMAFRAIAKDFPDIEVVAINDLLDPEYLAYMLKYDSVHGNFKGDIAVEGNNLIVNGKKIRLTAERE
PANLKWNEVGAELVIECTGFFLTKETCQKHIDAGAKKVVQSAPSKDDTPMFVYGVNHEKYAGEAIVSAASCTTNCLAPIA
KVLNDNWGIKRGLMSTVHAATATQKTVDGPSSKDWRGGRGILENIIPSSTGAAKAVGVVLPELKGKLTGMAFRVPTSDVS
VVDLTVELEKPAKYADICAAMKKASQSGDISKTLGYTDEKVVSTDFRGNGFSSIFDAEAGIALDDTFVKVVSWYDNEYGY
TCNMLRFVQHVAK

Sequences:

>Translated_333_residues
MAIKVGINGFGRIGRMAFRAIAKDFPDIEVVAINDLLDPEYLAYMLKYDSVHGNFKGDIAVEGNNLIVNGKKIRLTAERE
PANLKWNEVGAELVIECTGFFLTKETCQKHIDAGAKKVVQSAPSKDDTPMFVYGVNHEKYAGEAIVSAASCTTNCLAPIA
KVLNDNWGIKRGLMSTVHAATATQKTVDGPSSKDWRGGRGILENIIPSSTGAAKAVGVVLPELKGKLTGMAFRVPTSDVS
VVDLTVELEKPAKYADICAAMKKASQSGDISKTLGYTDEKVVSTDFRGNGFSSIFDAEAGIALDDTFVKVVSWYDNEYGY
TCNMLRFVQHVAK
>Mature_332_residues
AIKVGINGFGRIGRMAFRAIAKDFPDIEVVAINDLLDPEYLAYMLKYDSVHGNFKGDIAVEGNNLIVNGKKIRLTAEREP
ANLKWNEVGAELVIECTGFFLTKETCQKHIDAGAKKVVQSAPSKDDTPMFVYGVNHEKYAGEAIVSAASCTTNCLAPIAK
VLNDNWGIKRGLMSTVHAATATQKTVDGPSSKDWRGGRGILENIIPSSTGAAKAVGVVLPELKGKLTGMAFRVPTSDVSV
VDLTVELEKPAKYADICAAMKKASQSGDISKTLGYTDEKVVSTDFRGNGFSSIFDAEAGIALDDTFVKVVSWYDNEYGYT
CNMLRFVQHVAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=59.3373493975904, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=56.6265060240964, Blast_Score=371, Evalue=1e-103,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=69.6696696696697, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=38.2978723404255, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=58.4569732937685, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=58.4569732937685, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=58.4569732937685, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=57.8635014836795, Blast_Score=372, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=60.960960960961, Blast_Score=398, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=60.0600600600601, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=60.3603603603604, Blast_Score=392, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=61.7021276595745, Blast_Score=400, Evalue=1e-112,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=58.1818181818182, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=58.1818181818182, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=57.8787878787879, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=57.8787878787879, Blast_Score=378, Evalue=1e-105,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36004; Mature: 35873

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVGINGFGRIGRMAFRAIAKDFPDIEVVAINDLLDPEYLAYMLKYDSVHGNFKGDIA
CEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
VEGNNLIVNGKKIRLTAEREPANLKWNEVGAELVIECTGFFLTKETCQKHIDAGAKKVVQ
EECCEEEEECEEEEEEECCCCCCCCHHHHCCEEEEEECCCEEEHHHHHHHHHHHHHHHHH
SAPSKDDTPMFVYGVNHEKYAGEAIVSAASCTTNCLAPIAKVLNDNWGIKRGLMSTVHAA
CCCCCCCCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TATQKTVDGPSSKDWRGGRGILENIIPSSTGAAKAVGVVLPELKGKLTGMAFRVPTSDVS
HHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCE
VVDLTVELEKPAKYADICAAMKKASQSGDISKTLGYTDEKVVSTDFRGNGFSSIFDAEAG
EEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEECCCCCCCCHHHCCCCC
IALDDTFVKVVSWYDNEYGYTCNMLRFVQHVAK
CEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AIKVGINGFGRIGRMAFRAIAKDFPDIEVVAINDLLDPEYLAYMLKYDSVHGNFKGDIA
EEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
VEGNNLIVNGKKIRLTAEREPANLKWNEVGAELVIECTGFFLTKETCQKHIDAGAKKVVQ
EECCEEEEECEEEEEEECCCCCCCCHHHHCCEEEEEECCCEEEHHHHHHHHHHHHHHHHH
SAPSKDDTPMFVYGVNHEKYAGEAIVSAASCTTNCLAPIAKVLNDNWGIKRGLMSTVHAA
CCCCCCCCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TATQKTVDGPSSKDWRGGRGILENIIPSSTGAAKAVGVVLPELKGKLTGMAFRVPTSDVS
HHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCE
VVDLTVELEKPAKYADICAAMKKASQSGDISKTLGYTDEKVVSTDFRGNGFSSIFDAEAG
EEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEECCCCCCCCHHHCCCCC
IALDDTFVKVVSWYDNEYGYTCNMLRFVQHVAK
CEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852; 8366033 [H]