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The map label for this gene is groES

Identifier: 74316110

GI number: 74316110

Start: 98205

End: 98495

Strand: Reverse

Name: groES

Synonym: Tbd_0092

Alternate gene names: 74316110

Gene position: 98495-98205 (Counterclockwise)

Preceding gene: 74316115

Following gene: 74316109

Centisome position: 3.38

GC content: 60.48

Gene sequence:

>291_bases
ATGAAAATCCGTCCTCTGCACGACCGAGTGATTGTCAAACGCATGGAAGAAGAGCGCAAGACCGCCTCGGGCATCGTGAT
CCCCGACACCGCCGCCGAAAAACCCGATCAGGGTGAGATCGTGGCCGTCGGCGCGGGCAAGAAAGACGACCAGGGCAAGC
TGATTTCGCTGGACGTAAAGGTCGGCGACCGCGTGCTCTTCGGCAAGTACGCCGGCCAGACCGTCAAGGTCGAGGGCGAG
GAGCTCTTGGTGATGCGCGAAGAAGACATCATGGGCGTGGTCGAGCAGTAA

Upstream 100 bases:

>100_bases
AGCACTCTATGGCGGCGAGTGCTAATCACACCCTCGCCGCTTCCTTATTTTCGGGCAGCCGCGGCTGCCGGTTATCAACG
CTAGCAATGGAGACTTTGCA

Downstream 100 bases:

>100_bases
GCCGCCACCGCACGCAAACCCAACCGAATTCAAATATCTAGGAGTTAAGCAATGGCTGCAAAAGACGTACGTTTTGGTGA
TTCCGCGCGTCACCGCATGG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKIRPLHDRVIVKRMEEERKTASGIVIPDTAAEKPDQGEIVAVGAGKKDDQGKLISLDVKVGDRVLFGKYAGQTVKVEGE
ELLVMREEDIMGVVEQ

Sequences:

>Translated_96_residues
MKIRPLHDRVIVKRMEEERKTASGIVIPDTAAEKPDQGEIVAVGAGKKDDQGKLISLDVKVGDRVLFGKYAGQTVKVEGE
ELLVMREEDIMGVVEQ
>Mature_96_residues
MKIRPLHDRVIVKRMEEERKTASGIVIPDTAAEKPDQGEIVAVGAGKKDDQGKLISLDVKVGDRVLFGKYAGQTVKVEGE
ELLVMREEDIMGVVEQ

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=52.0833333333333, Blast_Score=94, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=41.9354838709677, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=41.7582417582418, Blast_Score=76, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=41.2371134020619, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=39.5833333333333, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_THIDA (Q3SMK0)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_313850.1
- ProteinModelPortal:   Q3SMK0
- SMR:   Q3SMK0
- STRING:   Q3SMK0
- GeneID:   3673870
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0092
- NMPDR:   fig|292415.3.peg.1054
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   FGQYAGQ
- PhylomeDB:   Q3SMK0
- ProtClustDB:   PRK00364
- BioCyc:   TDEN292415:TBD_0092-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10588; Mature: 10588

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRPLHDRVIVKRMEEERKTASGIVIPDTAAEKPDQGEIVAVGAGKKDDQGKLISLDVK
CCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEC
VGDRVLFGKYAGQTVKVEGEELLVMREEDIMGVVEQ
CCCEEEEECCCCCEEEECCCEEEEEECCCCEEEECC
>Mature Secondary Structure
MKIRPLHDRVIVKRMEEERKTASGIVIPDTAAEKPDQGEIVAVGAGKKDDQGKLISLDVK
CCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEC
VGDRVLFGKYAGQTVKVEGEELLVMREEDIMGVVEQ
CCCEEEEECCCCCEEEECCCEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA