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The map label for this gene is yhdG [H]

Identifier: 73539635

GI number: 73539635

Start: 2640477

End: 2641874

Strand: Direct

Name: yhdG [H]

Synonym: Reut_B5815

Alternate gene names: 73539635

Gene position: 2640477-2641874 (Clockwise)

Preceding gene: 73539634

Following gene: 73539636

Centisome position: 96.86

GC content: 61.59

Gene sequence:

>1398_bases
ATGAGCTTGTTTCGAACCAAAGACATTGACGCCATGCTGGTGAACAGCCACGTTGGCGGCCTGAAGAAGGTCCTGGGTCC
GGTGGACCTTGTACTGATGGGCATCGGTGCCATCATCGGGACCGGCATTTTTGTGCTTACCGGAACGGGCGCCTTGACCG
CCGGTCCCGCACTCACCATATCTTTCGTCATTGCCGCCATGGCCTGCGGCTTCGCCGCACTGTGCTATGCCGAGTTCGCC
TCCGCCATCCCTGTGTCGGGATCGATCTACACCTATAGCTATGCGACGCTGGGCGAAATCATCGCGTGGATGATCGGCTG
GGATCTTCTGCTCGAATACGGCCTCGCTACCTCGGCGGTGTCAGTGGGCTGGTCGGGATACTTCCAGTCGTTGGCCGCAG
GTTTCGGCCTGCATTTGCCGGCGGCGCTGACAGCAGCTCCAGGCGCAGTGCCGGGCGTGCAGACCTTGTTCAACCTGCCG
GCCTTCCTGATCATGCTGATTACCACGTGGGTGGTGTCCTGCGGCGTGCGTGAGTCGGCGCGCCTCAACAACGTGATGGT
GGCGATCAAGGTTGCAGTGGTCGTGTTGTTCATCGCAGTCGGCGTCTGGCACGTCAAACCGGCCAACTGGCAGCCATTCG
CGCCGTTCGGGGTATCCGGCATCTTCAATGCTGCAGCGCTGGTGTTCTTCGCCTTCATCGGCTTCGACGCGGTGACGTCG
GCCGCCGAGGAAGTACGCAATCCGCACCGCGACCTGCCGGTCGGCATCATCGGCTCGCTGGCGGTCTGCACAGTGCTATA
CGTGATTGTCGCGGCCATCATGACCGGCGTCGTTCCCTTCGCCAAGTTCGCCGGCATCGACCATCCGGTGTCGCTGGTTC
TGCAGTACGCGGGACAGAACTGGGTGGCCGGCTTTGTCGACCTGGGCGCGATTCTCGGCATGACCACTGTGATCCTGGTC
ATGACCTTTGGCCAGACTCGCGTCATCTTTGCCATGTCGCGCGACGGCCTGTTGCCCGCCAGGCTGTCGTCAGTACACCC
GGTACACGCCACGCCATTCTTTGCCACCTGGACTGTCGGTATCGTATTCGCGATGATCGCCGCATTCGTGCCGCTCAATG
TGCTGGCCGAGTTGATCAATATCGGCACGCTCTCCGCCTTCACGCTGATTTCGATCGCGGTGCTGGTGCTTCGCCGGACC
CGTCCCGAACTGCATAGGGCCTTCCGATGCCCCGGCGTGCCGGTGGTTCCGCTGCTATCGGTGGGCTTCTGCCTGTTTCT
GATGGCACACCTTCAAGCGCTGACCTGGATCGCATTTCTCACCTGGCTGGCGATCGGACTATCGGTCTACTTCCTGTACG
CGCGCCGCAATGCGGTGCTACACGAAGGCAGCAGGTAG

Upstream 100 bases:

>100_bases
CGGCAGCACGCTGCCCGGATGCCGTCACACCCGCATGACCCGTGGCCATCTCCGGCGCGGGCAGTGCGATCGCGCGGCAG
CACATGCAGGAGACACCTAT

Downstream 100 bases:

>100_bases
CGCGCGGGGCCACCTGTAAGCGCACACATGGACGCCACCGTTTGCCTGGCAACGATGGAATCCCGGTAGGACGCCAACCC
GGCGCTGGCGCGACACGATC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSLFRTKDIDAMLVNSHVGGLKKVLGPVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTISFVIAAMACGFAALCYAEFA
SAIPVSGSIYTYSYATLGEIIAWMIGWDLLLEYGLATSAVSVGWSGYFQSLAAGFGLHLPAALTAAPGAVPGVQTLFNLP
AFLIMLITTWVVSCGVRESARLNNVMVAIKVAVVVLFIAVGVWHVKPANWQPFAPFGVSGIFNAAALVFFAFIGFDAVTS
AAEEVRNPHRDLPVGIIGSLAVCTVLYVIVAAIMTGVVPFAKFAGIDHPVSLVLQYAGQNWVAGFVDLGAILGMTTVILV
MTFGQTRVIFAMSRDGLLPARLSSVHPVHATPFFATWTVGIVFAMIAAFVPLNVLAELINIGTLSAFTLISIAVLVLRRT
RPELHRAFRCPGVPVVPLLSVGFCLFLMAHLQALTWIAFLTWLAIGLSVYFLYARRNAVLHEGSR

Sequences:

>Translated_465_residues
MSLFRTKDIDAMLVNSHVGGLKKVLGPVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTISFVIAAMACGFAALCYAEFA
SAIPVSGSIYTYSYATLGEIIAWMIGWDLLLEYGLATSAVSVGWSGYFQSLAAGFGLHLPAALTAAPGAVPGVQTLFNLP
AFLIMLITTWVVSCGVRESARLNNVMVAIKVAVVVLFIAVGVWHVKPANWQPFAPFGVSGIFNAAALVFFAFIGFDAVTS
AAEEVRNPHRDLPVGIIGSLAVCTVLYVIVAAIMTGVVPFAKFAGIDHPVSLVLQYAGQNWVAGFVDLGAILGMTTVILV
MTFGQTRVIFAMSRDGLLPARLSSVHPVHATPFFATWTVGIVFAMIAAFVPLNVLAELINIGTLSAFTLISIAVLVLRRT
RPELHRAFRCPGVPVVPLLSVGFCLFLMAHLQALTWIAFLTWLAIGLSVYFLYARRNAVLHEGSR
>Mature_464_residues
SLFRTKDIDAMLVNSHVGGLKKVLGPVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTISFVIAAMACGFAALCYAEFAS
AIPVSGSIYTYSYATLGEIIAWMIGWDLLLEYGLATSAVSVGWSGYFQSLAAGFGLHLPAALTAAPGAVPGVQTLFNLPA
FLIMLITTWVVSCGVRESARLNNVMVAIKVAVVVLFIAVGVWHVKPANWQPFAPFGVSGIFNAAALVFFAFIGFDAVTSA
AEEVRNPHRDLPVGIIGSLAVCTVLYVIVAAIMTGVVPFAKFAGIDHPVSLVLQYAGQNWVAGFVDLGAILGMTTVILVM
TFGQTRVIFAMSRDGLLPARLSSVHPVHATPFFATWTVGIVFAMIAAFVPLNVLAELINIGTLSAFTLISIAVLVLRRTR
PELHRAFRCPGVPVVPLLSVGFCLFLMAHLQALTWIAFLTWLAIGLSVYFLYARRNAVLHEGSR

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=413, Percent_Identity=37.5302663438257, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=35.1039260969977, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI258614003, Length=489, Percent_Identity=32.1063394683027, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI258614005, Length=489, Percent_Identity=32.1063394683027, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI258645169, Length=489, Percent_Identity=32.1063394683027, Blast_Score=215, Evalue=9e-56,
Organism=Homo sapiens, GI110347453, Length=409, Percent_Identity=35.2078239608802, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI114326544, Length=428, Percent_Identity=33.6448598130841, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI114326550, Length=428, Percent_Identity=33.6448598130841, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI187423910, Length=477, Percent_Identity=26.6247379454927, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI7657591, Length=477, Percent_Identity=26.6247379454927, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI186910308, Length=462, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI186910306, Length=462, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI186910304, Length=462, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI115648063, Length=417, Percent_Identity=24.9400479616307, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI115648022, Length=417, Percent_Identity=24.9400479616307, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33286428, Length=456, Percent_Identity=25.6578947368421, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI71979932, Length=416, Percent_Identity=26.6826923076923, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI9790235, Length=293, Percent_Identity=26.2798634812287, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87081869, Length=462, Percent_Identity=25.3246753246753, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082023, Length=454, Percent_Identity=25.1101321585903, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081915, Length=425, Percent_Identity=23.7647058823529, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786694, Length=441, Percent_Identity=25.1700680272109, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786302, Length=441, Percent_Identity=22.6757369614512, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081708, Length=487, Percent_Identity=23.2032854209446, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788480, Length=448, Percent_Identity=23.2142857142857, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082250, Length=478, Percent_Identity=23.0125523012552, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790653, Length=482, Percent_Identity=22.4066390041494, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786789, Length=337, Percent_Identity=21.3649851632047, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=34.7087378640777, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17533459, Length=408, Percent_Identity=32.5980392156863, Blast_Score=201, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17531343, Length=408, Percent_Identity=32.1078431372549, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17568033, Length=421, Percent_Identity=26.3657957244656, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17537453, Length=378, Percent_Identity=23.2804232804233, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982612, Length=411, Percent_Identity=22.8710462287105, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319991, Length=313, Percent_Identity=26.8370607028754, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24667468, Length=422, Percent_Identity=35.3080568720379, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=35.7487922705314, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=35.7487922705314, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24668806, Length=431, Percent_Identity=35.0348027842227, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI21356285, Length=431, Percent_Identity=35.0348027842227, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24668802, Length=431, Percent_Identity=35.0348027842227, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI161077963, Length=411, Percent_Identity=37.4695863746959, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=31.7191283292978, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=31.7191283292978, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=31.7191283292978, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=31.7191283292978, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21357367, Length=418, Percent_Identity=27.511961722488, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221331183, Length=428, Percent_Identity=25.9345794392523, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17647653, Length=428, Percent_Identity=25.9345794392523, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24664379, Length=428, Percent_Identity=25.9345794392523, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45550968, Length=418, Percent_Identity=25.3588516746411, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19921172, Length=418, Percent_Identity=25.3588516746411, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24651635, Length=407, Percent_Identity=23.8329238329238, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24651633, Length=407, Percent_Identity=23.8329238329238, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641993, Length=429, Percent_Identity=24.9417249417249, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641995, Length=429, Percent_Identity=25.1748251748252, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49290; Mature: 49159

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLFRTKDIDAMLVNSHVGGLKKVLGPVDLVLMGIGAIIGTGIFVLTGTGALTAGPALTI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]