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The map label for this gene is ycgM [C]

Identifier: 73539629

GI number: 73539629

Start: 2633178

End: 2634026

Strand: Reverse

Name: ycgM [C]

Synonym: Reut_B5809

Alternate gene names: 73539629

Gene position: 2634026-2633178 (Counterclockwise)

Preceding gene: 73539630

Following gene: 73539628

Centisome position: 96.62

GC content: 59.84

Gene sequence:

>849_bases
GTGAAACTCGTAAGCTTCGAACATGCCGGAAGGGCCTCTTTCGGAGTCGTCCTCGGAGACGCAGTGCTGGATCTGGCCCC
CCACGCTGCTGCCGTCGGTCAAAGCCTTCGCGAAGCCCTCAGCAAAGGTGCATTGGGCTCGATTGCCGAAATCGCGAAGG
ATGGAGGGACTACGATTGCGTTGGACAAAGTCCGCCTGATGCCCGTAATTCCCGACCCGGCGAAGATTCTCTGTGTCGGC
ATCAACTACGCGTCTCACGTCAAGGAAACAGGTCGCGAGATGCCGAAGTACCCCATGTTCTTCACACGCTTCGCCGACTC
GCAGGTCGCGCACGACCAACCCATTATTCGCCCCCGTGCCTCGCAAAAGCTGGACTTTGAAGGCGAGCTGGCCGTGGTGA
TCGGACGCACGGCCCGCCATGTCCCTGGGGAGCAGGCATTGAACTATGTTGCCGGCTATTCCTGCTACAACGACGGAAGC
GTTCGCGACTGGCAAAAGCACACCATTCAGTTCACACCGGGCAAGAACTTTCCCCAGACCGGCGCGTTAGGCCCATGGCT
CGTAACAACCGATGAGATTCGCGATCCGTCCGCGCTGTCGCTGACCACGCGGCTCAACGGCGAAGTGGTGCAGGCCGCCA
CGACGGACGACCTCATCTTCAGCGTAAGCGAAGTGATCGCCTATTGCTCAACCTTCACGGAGCTACGCGCTGGCGACGTC
ATCATTACCGGAACGACAGGCGGCGTCGGCGCGTTCCGTGAGCCTCCGCTATGGATGAAGCCCGGCGACGTGGTGGAAGT
GGAAATCTCCAAGATTGGCGTGCTGCGCAACACAATCCAGGACGAATGA

Upstream 100 bases:

>100_bases
CTCTTAACATAGTACTTTATCTTTTTTCTCACTATATGCGAAACTAGAACACATAAAGACGCTGCACTTCTGCTAGCGTC
TCCTCGCAAAGGAGAGAAAA

Downstream 100 bases:

>100_bases
CGCAGCCGTGGGCGAACGCCGCACGATCCAGCGGTCGTCCACGAAGGAGACAACCATGCAAGACGCGAACGCGCTCAACA
CATCCGTGTTGATTGTCGGC

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLVSFEHAGRASFGVVLGDAVLDLAPHAAAVGQSLREALSKGALGSIAEIAKDGGTTIALDKVRLMPVIPDPAKILCVG
INYASHVKETGREMPKYPMFFTRFADSQVAHDQPIIRPRASQKLDFEGELAVVIGRTARHVPGEQALNYVAGYSCYNDGS
VRDWQKHTIQFTPGKNFPQTGALGPWLVTTDEIRDPSALSLTTRLNGEVVQAATTDDLIFSVSEVIAYCSTFTELRAGDV
IITGTTGGVGAFREPPLWMKPGDVVEVEISKIGVLRNTIQDE

Sequences:

>Translated_282_residues
MKLVSFEHAGRASFGVVLGDAVLDLAPHAAAVGQSLREALSKGALGSIAEIAKDGGTTIALDKVRLMPVIPDPAKILCVG
INYASHVKETGREMPKYPMFFTRFADSQVAHDQPIIRPRASQKLDFEGELAVVIGRTARHVPGEQALNYVAGYSCYNDGS
VRDWQKHTIQFTPGKNFPQTGALGPWLVTTDEIRDPSALSLTTRLNGEVVQAATTDDLIFSVSEVIAYCSTFTELRAGDV
IITGTTGGVGAFREPPLWMKPGDVVEVEISKIGVLRNTIQDE
>Mature_282_residues
MKLVSFEHAGRASFGVVLGDAVLDLAPHAAAVGQSLREALSKGALGSIAEIAKDGGTTIALDKVRLMPVIPDPAKILCVG
INYASHVKETGREMPKYPMFFTRFADSQVAHDQPIIRPRASQKLDFEGELAVVIGRTARHVPGEQALNYVAGYSCYNDGS
VRDWQKHTIQFTPGKNFPQTGALGPWLVTTDEIRDPSALSLTTRLNGEVVQAATTDDLIFSVSEVIAYCSTFTELRAGDV
IITGTTGGVGAFREPPLWMKPGDVVEVEISKIGVLRNTIQDE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=287, Percent_Identity=37.2822299651568, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI40786394, Length=287, Percent_Identity=36.9337979094077, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI215422413, Length=183, Percent_Identity=36.0655737704918, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI13654274, Length=183, Percent_Identity=36.0655737704918, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI66348062, Length=184, Percent_Identity=35.8695652173913, Blast_Score=117, Evalue=8e-27,
Organism=Escherichia coli, GI1787428, Length=184, Percent_Identity=35.3260869565217, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17557057, Length=200, Percent_Identity=33, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28572127, Length=238, Percent_Identity=42.0168067226891, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=34.4036697247706, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=31.6037735849057, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 30379; Mature: 30379

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVSFEHAGRASFGVVLGDAVLDLAPHAAAVGQSLREALSKGALGSIAEIAKDGGTTIA
CCEECCCCCCCCEEHEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEE
LDKVRLMPVIPDPAKILCVGINYASHVKETGREMPKYPMFFTRFADSQVAHDQPIIRPRA
EEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
SQKLDFEGELAVVIGRTARHVPGEQALNYVAGYSCYNDGSVRDWQKHTIQFTPGKNFPQT
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GALGPWLVTTDEIRDPSALSLTTRLNGEVVQAATTDDLIFSVSEVIAYCSTFTELRAGDV
CCCCCEEEEHHCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCE
IITGTTGGVGAFREPPLWMKPGDVVEVEISKIGVLRNTIQDE
EEECCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLVSFEHAGRASFGVVLGDAVLDLAPHAAAVGQSLREALSKGALGSIAEIAKDGGTTIA
CCEECCCCCCCCEEHEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEE
LDKVRLMPVIPDPAKILCVGINYASHVKETGREMPKYPMFFTRFADSQVAHDQPIIRPRA
EEEEEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
SQKLDFEGELAVVIGRTARHVPGEQALNYVAGYSCYNDGSVRDWQKHTIQFTPGKNFPQT
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GALGPWLVTTDEIRDPSALSLTTRLNGEVVQAATTDDLIFSVSEVIAYCSTFTELRAGDV
CCCCCEEEEHHCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCE
IITGTTGGVGAFREPPLWMKPGDVVEVEISKIGVLRNTIQDE
EEECCCCCCCCCCCCCCEECCCCEEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]