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The map label for this gene is kipR [H]

Identifier: 73539630

GI number: 73539630

Start: 2634405

End: 2635265

Strand: Reverse

Name: kipR [H]

Synonym: Reut_B5810

Alternate gene names: 73539630

Gene position: 2635265-2634405 (Counterclockwise)

Preceding gene: 73539631

Following gene: 73539629

Centisome position: 96.67

GC content: 58.89

Gene sequence:

>861_bases
TTGCCGTGCGGGTATAACCGAATCGCAAAACCCAACATTCTTGCAAGACAGGAAAGGACCGCTGACATGGCAACGGATCG
CGCGCTCGGCGTGCTGACACTCTTCTCCCTGGACAAGCCAATGTGGACGGTTGACGAAATCGGCGAGCAGCTAGGGGTTT
CGTCCAGCAGCGCCTATCGGTACCTCTCCAATCTCTTGGAACTTGGGCTCGTTGCAAGTGCAGGTGCGAAGCGCTATGTG
CTGGGCCCTGCGATCATTCAACTGGATCGGCAGATCCAATTGACCGACCCGATGTTGCAAGCTGCGCGCCCGGTCATGGC
CGAACTTGTTGATTTCGCGCCGAGTGGATCCGTGATGTTGCTATGCCGGGCCTTTGGTGATTCCGTCCTGTGCGTCCATC
AGGTACTCGGTAAAGGACCTCAGCCAATCGTGAGCTACGAACGAGGGCGTCCCATGCTCATGTTCCGGGGCGCGACGTCT
CGCATCATTCTTGCCTTCCAGCAGACGCGAATGCTGCAAGCAATCTACGAAAAACACCATGTCGAGATTGCCGCTGCAGG
GCTCGGAGATGATTGGAGCACCTTCCGCCTTGGCCTGAGCCGTCTCCGGCGTATGGGTTATGCCGTCTCGCACGGCGAAA
TCGATCCAGGCCGGGTCGGTATCGCGGCGCCTATTCTTGGCGAGGATGGTCGCGCGGCTGGCAGCTTGAGCTATGTGGTG
GCGGAAGCCAGCGTGGATCAAGGCTCCATCGCAAGGTTGTCCCACATTCTGATGGGAGCTGCGCACGAAATCTCGATCTC
GATGCTTGCCCAAGGCAAGGACGGTACAAGCGCCGCCGACGCACAGTCTGCCGGACACTAG

Upstream 100 bases:

>100_bases
GAAGGCCATGGAATGCGCGTCACGAAGAACAAGGTTGGCCTCGCTGTCCGCAACTTTTGTCATTCTGCGCAAAAAATGAA
CGACCATGTTGGCATAATCC

Downstream 100 bases:

>100_bases
CACACCTACTTCCCATTCAGGGCCCCGCCTCTTCTTCGAGCCACCGGCAAAGACGCATGGGGAGATCCCCTCCGTCTTAA
CCAATGCGCCCGAGCGCCTG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPCGYNRIAKPNILARQERTADMATDRALGVLTLFSLDKPMWTVDEIGEQLGVSSSSAYRYLSNLLELGLVASAGAKRYV
LGPAIIQLDRQIQLTDPMLQAARPVMAELVDFAPSGSVMLLCRAFGDSVLCVHQVLGKGPQPIVSYERGRPMLMFRGATS
RIILAFQQTRMLQAIYEKHHVEIAAAGLGDDWSTFRLGLSRLRRMGYAVSHGEIDPGRVGIAAPILGEDGRAAGSLSYVV
AEASVDQGSIARLSHILMGAAHEISISMLAQGKDGTSAADAQSAGH

Sequences:

>Translated_286_residues
MPCGYNRIAKPNILARQERTADMATDRALGVLTLFSLDKPMWTVDEIGEQLGVSSSSAYRYLSNLLELGLVASAGAKRYV
LGPAIIQLDRQIQLTDPMLQAARPVMAELVDFAPSGSVMLLCRAFGDSVLCVHQVLGKGPQPIVSYERGRPMLMFRGATS
RIILAFQQTRMLQAIYEKHHVEIAAAGLGDDWSTFRLGLSRLRRMGYAVSHGEIDPGRVGIAAPILGEDGRAAGSLSYVV
AEASVDQGSIARLSHILMGAAHEISISMLAQGKDGTSAADAQSAGH
>Mature_285_residues
PCGYNRIAKPNILARQERTADMATDRALGVLTLFSLDKPMWTVDEIGEQLGVSSSSAYRYLSNLLELGLVASAGAKRYVL
GPAIIQLDRQIQLTDPMLQAARPVMAELVDFAPSGSVMLLCRAFGDSVLCVHQVLGKGPQPIVSYERGRPMLMFRGATSR
IILAFQQTRMLQAIYEKHHVEIAAAGLGDDWSTFRLGLSRLRRMGYAVSHGEIDPGRVGIAAPILGEDGRAAGSLSYVVA
EASVDQGSIARLSHILMGAAHEISISMLAQGKDGTSAADAQSAGH

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30648; Mature: 30517

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCGYNRIAKPNILARQERTADMATDRALGVLTLFSLDKPMWTVDEIGEQLGVSSSSAYR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCHHHHH
YLSNLLELGLVASAGAKRYVLGPAIIQLDRQIQLTDPMLQAARPVMAELVDFAPSGSVML
HHHHHHHHHHHHCCCCCEEEECHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEE
LCRAFGDSVLCVHQVLGKGPQPIVSYERGRPMLMFRGATSRIILAFQQTRMLQAIYEKHH
EEEHHCCCHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHC
VEIAAAGLGDDWSTFRLGLSRLRRMGYAVSHGEIDPGRVGIAAPILGEDGRAAGSLSYVV
EEEEEECCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCEEEEECEECCCCCCCCCEEEEE
AEASVDQGSIARLSHILMGAAHEISISMLAQGKDGTSAADAQSAGH
EECCCCCCHHHHHHHHHHCCHHHEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PCGYNRIAKPNILARQERTADMATDRALGVLTLFSLDKPMWTVDEIGEQLGVSSSSAYR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCHHHHH
YLSNLLELGLVASAGAKRYVLGPAIIQLDRQIQLTDPMLQAARPVMAELVDFAPSGSVML
HHHHHHHHHHHHCCCCCEEEECHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEE
LCRAFGDSVLCVHQVLGKGPQPIVSYERGRPMLMFRGATSRIILAFQQTRMLQAIYEKHH
EEEHHCCCHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHC
VEIAAAGLGDDWSTFRLGLSRLRRMGYAVSHGEIDPGRVGIAAPILGEDGRAAGSLSYVV
EEEEEECCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCEEEEECEECCCCCCCCCEEEEE
AEASVDQGSIARLSHILMGAAHEISISMLAQGKDGTSAADAQSAGH
EECCCCCCHHHHHHHHHHCCHHHEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]