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The map label for this gene is luxQ [H]

Identifier: 73538799

GI number: 73538799

Start: 1699977

End: 1700876

Strand: Direct

Name: luxQ [H]

Synonym: Reut_B4974

Alternate gene names: 73538799

Gene position: 1699977-1700876 (Clockwise)

Preceding gene: 73538798

Following gene: 73538800

Centisome position: 62.36

GC content: 62.89

Gene sequence:

>900_bases
ATGAACGCACCCGCTTCCACCCCCCAAGACATTGCCAGCCTGCAGGCAGCACTGGACGCGCGTACGCGGGAAGTGGAGAC
CTTGCGCACCGAGATCGACGAGACCAACCGCGGTGTCGTAGCGCTCTACGCCGAACTCGACATCCAGGCGGAACAGCTTC
GGCAGGCCACCGAACTCAAGAGCCGCTTTCTGGCCTATATGAGCCACGAGTTCCGCACGCCGATCGTGGCGATTCAAAGC
ATCACGCGTTTGCTGATCGACCGTGTCGATGGCCCACTTACCCCGGAACAGGAGAAGCAGGTCAGGTTCGTGCGCGATAC
GGCCGCCGAGTTTGCCGGCATGGTCAATGACCTGCTGGACCTGGCGCGCCTGGAAGCGGGCCGCGTCGATGTATCGCCGG
CTTGGTTCGACATGGTGGCGCTGTTCGATGCGCTGCGTGGCATGTTCAAGCCGGTGCTGACCAATCCCGAGGTATCGCTG
ATCTTCGAGGAGCCACATGACGTGAGCAAGTTGTTCAGCGACGACCGCAAGGTGTCGCAAATCCTGCGCAACTTTATCTC
GAACGCGCTGAAATTTACCCCCAGTGGTGAAGTGCGGGTTTCGGCGAAGCGCGAGCCTGGCGACATGATCATGTTCTCCG
TGCGCGATACCGGCATCGGGATACCGGCGGAGGCGCATGGCGCGGTGTTCGGTGACTTCGTGCAGGTCGATTCGCCGCTG
CAGCGCCGCTATCGCGGCTCGGGACTCGGACTGGCGCTCAGCAAGCGACTGGCGGAACTGCTCGGCGGCTCGATAGGCTT
CGAAAGTCAGGTCGGGGTCGGTTCGCGCTTCTACGTGACCTTGCCCGCGACGTTCCCGAGCCAGAGCCAGGCGCCCGCTG
GAGACGGTCATGCCGGATAG

Upstream 100 bases:

>100_bases
CAACGCGACCCCGCGCTGATTGCCGCCTTTGTGCTCTGGAGGTTCTGCCGCGGACGGGACGATGCCACGGTGGTGGTCAT
CCGCCGCGCGGAGGTCTGAA

Downstream 100 bases:

>100_bases
CGTCGACGTCGTCCCGGGCGGACACGCAGCGGGCGGCGCCGTCCAGCCGCTGGTGCTGGTGGTGGACGACAATCCCGTCA
CGCGGTACGCGACGGTGCGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNAPASTPQDIASLQAALDARTREVETLRTEIDETNRGVVALYAELDIQAEQLRQATELKSRFLAYMSHEFRTPIVAIQS
ITRLLIDRVDGPLTPEQEKQVRFVRDTAAEFAGMVNDLLDLARLEAGRVDVSPAWFDMVALFDALRGMFKPVLTNPEVSL
IFEEPHDVSKLFSDDRKVSQILRNFISNALKFTPSGEVRVSAKREPGDMIMFSVRDTGIGIPAEAHGAVFGDFVQVDSPL
QRRYRGSGLGLALSKRLAELLGGSIGFESQVGVGSRFYVTLPATFPSQSQAPAGDGHAG

Sequences:

>Translated_299_residues
MNAPASTPQDIASLQAALDARTREVETLRTEIDETNRGVVALYAELDIQAEQLRQATELKSRFLAYMSHEFRTPIVAIQS
ITRLLIDRVDGPLTPEQEKQVRFVRDTAAEFAGMVNDLLDLARLEAGRVDVSPAWFDMVALFDALRGMFKPVLTNPEVSL
IFEEPHDVSKLFSDDRKVSQILRNFISNALKFTPSGEVRVSAKREPGDMIMFSVRDTGIGIPAEAHGAVFGDFVQVDSPL
QRRYRGSGLGLALSKRLAELLGGSIGFESQVGVGSRFYVTLPATFPSQSQAPAGDGHAG
>Mature_299_residues
MNAPASTPQDIASLQAALDARTREVETLRTEIDETNRGVVALYAELDIQAEQLRQATELKSRFLAYMSHEFRTPIVAIQS
ITRLLIDRVDGPLTPEQEKQVRFVRDTAAEFAGMVNDLLDLARLEAGRVDVSPAWFDMVALFDALRGMFKPVLTNPEVSL
IFEEPHDVSKLFSDDRKVSQILRNFISNALKFTPSGEVRVSAKREPGDMIMFSVRDTGIGIPAEAHGAVFGDFVQVDSPL
QRRYRGSGLGLALSKRLAELLGGSIGFESQVGVGSRFYVTLPATFPSQSQAPAGDGHAG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=36.1344537815126, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=30.2583025830258, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=31.8681318681319, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=30.46875, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87081816, Length=289, Percent_Identity=32.1799307958478, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=27.1186440677966, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=25.2066115702479, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=27.0386266094421, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=25, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=25.6756756756757, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=23.4432234432234, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=27.1551724137931, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=28.7610619469027, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=47.2972972972973, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 32766; Mature: 32766

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPASTPQDIASLQAALDARTREVETLRTEIDETNRGVVALYAELDIQAEQLRQATELK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHH
SRFLAYMSHEFRTPIVAIQSITRLLIDRVDGPLTPEQEKQVRFVRDTAAEFAGMVNDLLD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LARLEAGRVDVSPAWFDMVALFDALRGMFKPVLTNPEVSLIFEEPHDVSKLFSDDRKVSQ
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCHHHHH
ILRNFISNALKFTPSGEVRVSAKREPGDMIMFSVRDTGIGIPAEAHGAVFGDFVQVDSPL
HHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHH
QRRYRGSGLGLALSKRLAELLGGSIGFESQVGVGSRFYVTLPATFPSQSQAPAGDGHAG
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAPASTPQDIASLQAALDARTREVETLRTEIDETNRGVVALYAELDIQAEQLRQATELK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHH
SRFLAYMSHEFRTPIVAIQSITRLLIDRVDGPLTPEQEKQVRFVRDTAAEFAGMVNDLLD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LARLEAGRVDVSPAWFDMVALFDALRGMFKPVLTNPEVSLIFEEPHDVSKLFSDDRKVSQ
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCHHHHH
ILRNFISNALKFTPSGEVRVSAKREPGDMIMFSVRDTGIGIPAEAHGAVFGDFVQVDSPL
HHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHH
QRRYRGSGLGLALSKRLAELLGGSIGFESQVGVGSRFYVTLPATFPSQSQAPAGDGHAG
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]