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The map label for this gene is caiD [C]

Identifier: 73538605

GI number: 73538605

Start: 1479633

End: 1480403

Strand: Reverse

Name: caiD [C]

Synonym: Reut_B4780

Alternate gene names: 73538605

Gene position: 1480403-1479633 (Counterclockwise)

Preceding gene: 73538606

Following gene: 73538604

Centisome position: 54.3

GC content: 66.02

Gene sequence:

>771_bases
ATGAGCGAGACTTCGCAAGGACAGGCGCCTGAACTGACCGTCGGTGGTCACGTCGCCGTCATCACGCTGCGACGCCCAGA
GGTGGCGAACCGGCTGGAGCCGGAAGACCTGGACCTGTTGCTCAGTTATCTGGAGACCGTGAACGCGGACAGCCAGATTC
GCGTACTGCGCCTCGAAGGACAGGGCCGTCATTTCTGTAGTGGCTTCAACATCGGCCGGCTCGGCGGTGCCGATGTGGGC
GAGCGTTTCGAGGCACTCGCCAACGCATGGGAGCACGCGCGGCCGGTGACCATCGCGGTGCTGCATGGCGGTGCGTACGG
CGGGGCCACGGATCTCGCGCTCGCTTGTGATTTTCGCTTCGGCGCGGCCGCCACCGAGATGTCGGTACCAGCCGCGCGCC
TGGGGCTGCTGTTCTATCGCGGCGGCATGGAGCGTTATGTCACTCGCCTTGGCCTGGCCACGGCCAAGCGCGTGCTGCTG
ATGGCTGACAAGTTCAACGCGGCCGAGATGCTGGCCTGTGGTTACCTAGACCGTCTGGAAGACAACCCCGAGGCGCTGCG
CGCGCTAGTGCAGCGGTGGAGTGCAGAGTTGGCTGGCATGGCGCCGCTGGCACTGCTCGGCATGAAGAAGCACATGAACC
GCATTGCGCGCGGTGAACTCGATACCGTCGAACTCGCCCGCGATATCGCCGCGGCCGATGCCTCCGACGATCTGCGCGAG
GGTGCGCTGGCCTGGCGGGAAAAGCGCGCGCCGCGTTTCAACGGCCGCTGA

Upstream 100 bases:

>100_bases
CAGGACCGCGAGGCGACCGAAGCCGCCATTCTCAAGCGCGTGGAGGCAGGCGAGACCACCATGCGGATCTACGGCTTTCA
CTGAACCGGAGCCGGATGCC

Downstream 100 bases:

>100_bases
TGGGAATGTACTGAATGAGCCAAGACAATTATTTTTCCCGCATGCTGCGTGGCGAGGCGCCCGTGCCGGCCGTTGCCGGC
ACGCTAGGCGGCGTGATCCG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSETSQGQAPELTVGGHVAVITLRRPEVANRLEPEDLDLLLSYLETVNADSQIRVLRLEGQGRHFCSGFNIGRLGGADVG
ERFEALANAWEHARPVTIAVLHGGAYGGATDLALACDFRFGAAATEMSVPAARLGLLFYRGGMERYVTRLGLATAKRVLL
MADKFNAAEMLACGYLDRLEDNPEALRALVQRWSAELAGMAPLALLGMKKHMNRIARGELDTVELARDIAAADASDDLRE
GALAWREKRAPRFNGR

Sequences:

>Translated_256_residues
MSETSQGQAPELTVGGHVAVITLRRPEVANRLEPEDLDLLLSYLETVNADSQIRVLRLEGQGRHFCSGFNIGRLGGADVG
ERFEALANAWEHARPVTIAVLHGGAYGGATDLALACDFRFGAAATEMSVPAARLGLLFYRGGMERYVTRLGLATAKRVLL
MADKFNAAEMLACGYLDRLEDNPEALRALVQRWSAELAGMAPLALLGMKKHMNRIARGELDTVELARDIAAADASDDLRE
GALAWREKRAPRFNGR
>Mature_255_residues
SETSQGQAPELTVGGHVAVITLRRPEVANRLEPEDLDLLLSYLETVNADSQIRVLRLEGQGRHFCSGFNIGRLGGADVGE
RFEALANAWEHARPVTIAVLHGGAYGGATDLALACDFRFGAAATEMSVPAARLGLLFYRGGMERYVTRLGLATAKRVLLM
ADKFNAAEMLACGYLDRLEDNPEALRALVQRWSAELAGMAPLALLGMKKHMNRIARGELDTVELARDIAAADASDDLREG
ALAWREKRAPRFNGR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=30.0380228136882, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787660, Length=252, Percent_Identity=30.952380952381, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788597, Length=249, Percent_Identity=25.3012048192771, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=27.0491803278689, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=266, Percent_Identity=27.0676691729323, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=262, Percent_Identity=25.1908396946565, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=28.2868525896414, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27845; Mature: 27714

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETSQGQAPELTVGGHVAVITLRRPEVANRLEPEDLDLLLSYLETVNADSQIRVLRLEG
CCCCCCCCCCEEEECCEEEEEEEECCHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
QGRHFCSGFNIGRLGGADVGERFEALANAWEHARPVTIAVLHGGAYGGATDLALACDFRF
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCC
GAAATEMSVPAARLGLLFYRGGMERYVTRLGLATAKRVLLMADKFNAAEMLACGYLDRLE
CCCHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCC
DNPEALRALVQRWSAELAGMAPLALLGMKKHMNRIARGELDTVELARDIAAADASDDLRE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
GALAWREKRAPRFNGR
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SETSQGQAPELTVGGHVAVITLRRPEVANRLEPEDLDLLLSYLETVNADSQIRVLRLEG
CCCCCCCCCEEEECCEEEEEEEECCHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
QGRHFCSGFNIGRLGGADVGERFEALANAWEHARPVTIAVLHGGAYGGATDLALACDFRF
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCC
GAAATEMSVPAARLGLLFYRGGMERYVTRLGLATAKRVLLMADKFNAAEMLACGYLDRLE
CCCHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCC
DNPEALRALVQRWSAELAGMAPLALLGMKKHMNRIARGELDTVELARDIAAADASDDLRE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
GALAWREKRAPRFNGR
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA