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The map label for this gene is proA [H]

Identifier: 73538606

GI number: 73538606

Start: 1480420

End: 1481082

Strand: Reverse

Name: proA [H]

Synonym: Reut_B4781

Alternate gene names: 73538606

Gene position: 1481082-1480420 (Counterclockwise)

Preceding gene: 73538607

Following gene: 73538605

Centisome position: 54.33

GC content: 67.12

Gene sequence:

>663_bases
ATGGCGGAACACGACGCAACCAGCACCACGATCCGCGACTTTGAACGCGTAAGCGCCGGGATCATCAATGACGCACGTGC
GCTGCCCACCGCCACGCTGCATGAAGCGGGCGGCAAGATCGGCGTGGTGTCGCCGGCCATCAAGCCCGTCGCACCGGAGT
TCCGCATCTGCGGCCCGGCGCTGACGGTCCATTCGCCGGGCGGCGATAACCTGTGGCTGCACCGCGCCATCGACATCGCG
CAGCCCGGCGACGTACTCGTGGTGCATGTGAGCGGCGCGTATGACCATGGCTACTGGGGCGAGATCATGACCACCGCGGC
CAAGGTGAAGCAACTCGGCGGCCTCATCATAGACGGCTGCGTGCGCGACGGCGTGCTACTTGACGAGATTGGTTTCCCGG
TATTCGCACGCGGCCTGTGCATCCGTGGCACGGGCAAGGACTATGGCGCGATCGGCTGGCTCAATGCGCCGGTGCTGATT
GGTGGCGCGCGTGTCGAAGCGGGCGACCTGGTCGTGGGCGACCGCGACGGCGTGGTGGTCGTGCCGCGCAAGCGCGCAGC
CGAGGTCGTCGGCAAGGCGCAGGACCGCGAGGCGACCGAAGCCGCCATTCTCAAGCGCGTGGAGGCAGGCGAGACCACCA
TGCGGATCTACGGCTTTCACTGA

Upstream 100 bases:

>100_bases
CCGAGAACGCGATCCGCGAAGCCGTGCGCGGCGGCATGCGCCTGGACGAGGCGCGACGCCAGTTCCGCTATCACCAGCTG
CAGACGAAGGGAGCCTGATC

Downstream 100 bases:

>100_bases
ACCGGAGCCGGATGCCATGAGCGAGACTTCGCAAGGACAGGCGCCTGAACTGACCGTCGGTGGTCACGTCGCCGTCATCA
CGCTGCGACGCCCAGAGGTG

Product: dimethylmenaquinone methyltransferase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MAEHDATSTTIRDFERVSAGIINDARALPTATLHEAGGKIGVVSPAIKPVAPEFRICGPALTVHSPGGDNLWLHRAIDIA
QPGDVLVVHVSGAYDHGYWGEIMTTAAKVKQLGGLIIDGCVRDGVLLDEIGFPVFARGLCIRGTGKDYGAIGWLNAPVLI
GGARVEAGDLVVGDRDGVVVVPRKRAAEVVGKAQDREATEAAILKRVEAGETTMRIYGFH

Sequences:

>Translated_220_residues
MAEHDATSTTIRDFERVSAGIINDARALPTATLHEAGGKIGVVSPAIKPVAPEFRICGPALTVHSPGGDNLWLHRAIDIA
QPGDVLVVHVSGAYDHGYWGEIMTTAAKVKQLGGLIIDGCVRDGVLLDEIGFPVFARGLCIRGTGKDYGAIGWLNAPVLI
GGARVEAGDLVVGDRDGVVVVPRKRAAEVVGKAQDREATEAAILKRVEAGETTMRIYGFH
>Mature_219_residues
AEHDATSTTIRDFERVSAGIINDARALPTATLHEAGGKIGVVSPAIKPVAPEFRICGPALTVHSPGGDNLWLHRAIDIAQ
PGDVLVVHVSGAYDHGYWGEIMTTAAKVKQLGGLIIDGCVRDGVLLDEIGFPVFARGLCIRGTGKDYGAIGWLNAPVLIG
GARVEAGDLVVGDRDGVVVVPRKRAAEVVGKAQDREATEAAILKRVEAGETTMRIYGFH

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 23193; Mature: 23062

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHDATSTTIRDFERVSAGIINDARALPTATLHEAGGKIGVVSPAIKPVAPEFRICGPA
CCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHCCCEEEEECCCCCCCCCCEEEECCE
LTVHSPGGDNLWLHRAIDIAQPGDVLVVHVSGAYDHGYWGEIMTTAAKVKQLGGLIIDGC
EEEECCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECH
VRDGVLLDEIGFPVFARGLCIRGTGKDYGAIGWLNAPVLIGGARVEAGDLVVGDRDGVVV
HCCCEEEECCCCCHHHCCEEEECCCCCCCEEEEECCCEEEECCEEECCCEEEECCCCEEE
VPRKRAAEVVGKAQDREATEAAILKRVEAGETTMRIYGFH
ECCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure 
AEHDATSTTIRDFERVSAGIINDARALPTATLHEAGGKIGVVSPAIKPVAPEFRICGPA
CCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHCCCEEEEECCCCCCCCCCEEEECCE
LTVHSPGGDNLWLHRAIDIAQPGDVLVVHVSGAYDHGYWGEIMTTAAKVKQLGGLIIDGC
EEEECCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECH
VRDGVLLDEIGFPVFARGLCIRGTGKDYGAIGWLNAPVLIGGARVEAGDLVVGDRDGVVV
HCCCEEEECCCCCHHHCCEEEECCCCCCCEEEEECCCEEEECCEEECCCEEEECCCCEEE
VPRKRAAEVVGKAQDREATEAAILKRVEAGETTMRIYGFH
ECCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]