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The map label for this gene is nahD [H]

Identifier: 73538548

GI number: 73538548

Start: 1423746

End: 1424336

Strand: Reverse

Name: nahD [H]

Synonym: Reut_B4723

Alternate gene names: 73538548

Gene position: 1424336-1423746 (Counterclockwise)

Preceding gene: 73538551

Following gene: 73538543

Centisome position: 52.25

GC content: 66.16

Gene sequence:

>591_bases
GTGACCAAGACGGTGGAGTTCTACTTCGATGTGGGCAGTCCGGCCTCCTACCTGGCCTGGACGCAGCTTCCCGTGCTCTG
TGCGCAAGCCGGCGCGCAACTCGTCTACAAGCCGATGCTATTGGGCGGCGTGTTCCAGGCCACCGGCAATGCATCGCCGG
CCGCGGTGCCGGCGAAGGGGCGCTACGTCTCGCACGACCTGGCCCGCTTTGCGCGGCGCTACGGCGTGCCGCTTGCGCGG
AACCCGCACTTTCCCATCATCACGCTGATGCTCATGCGCGCGGCCACCGCGGTCCAGTTGCGCGAGCCGGAGCGGTTCGA
CCACTTCCTGTCCACGGTTTTCCAGGCCATCTGGGTGGATTCGCTCAACCTGAATGACATGGGGCTGACCGCGCAGACGC
TCGCGCGCGGCGGGTTCGACGCAGGTCAGATCGAAGCGTGGGTCAGCGATCCCGAGATCAAGGCGGCGTTGAAGGCCACC
ACCGACGAGGCGCTGCAGCGTGGCGTCTTCGGCGCCCCGACGATGTTCGTCGGGCAGGAGATGTTCTTCGGACAGGACCG
GCTGGACTTTGTACAGGAAGCCCTAGGCTGA

Upstream 100 bases:

>100_bases
GTCTTGGTGTAGCGCATGGCAGCGGACTGGCAGTTGACATCAACTGAACCATAGCATATCGTCCGTTAACTAAACGTACG
TTAAATAAAAGGAGGATGAC

Downstream 100 bases:

>100_bases
CCGACGTGTTGCGCCGGCCAGGCCTGCAACGCTTGCCGAACACCCGCTCGCCGCGCGTGCTCACCACTCTTGCCATCAGG
CTCGGTGGTGAAGCGTCGTC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTKTVEFYFDVGSPASYLAWTQLPVLCAQAGAQLVYKPMLLGGVFQATGNASPAAVPAKGRYVSHDLARFARRYGVPLAR
NPHFPIITLMLMRAATAVQLREPERFDHFLSTVFQAIWVDSLNLNDMGLTAQTLARGGFDAGQIEAWVSDPEIKAALKAT
TDEALQRGVFGAPTMFVGQEMFFGQDRLDFVQEALG

Sequences:

>Translated_196_residues
MTKTVEFYFDVGSPASYLAWTQLPVLCAQAGAQLVYKPMLLGGVFQATGNASPAAVPAKGRYVSHDLARFARRYGVPLAR
NPHFPIITLMLMRAATAVQLREPERFDHFLSTVFQAIWVDSLNLNDMGLTAQTLARGGFDAGQIEAWVSDPEIKAALKAT
TDEALQRGVFGAPTMFVGQEMFFGQDRLDFVQEALG
>Mature_195_residues
TKTVEFYFDVGSPASYLAWTQLPVLCAQAGAQLVYKPMLLGGVFQATGNASPAAVPAKGRYVSHDLARFARRYGVPLARN
PHFPIITLMLMRAATAVQLREPERFDHFLSTVFQAIWVDSLNLNDMGLTAQTLARGGFDAGQIEAWVSDPEIKAALKATT
DEALQRGVFGAPTMFVGQEMFFGQDRLDFVQEALG

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705704, Length=215, Percent_Identity=28.8372093023256, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI219842333, Length=212, Percent_Identity=30.188679245283, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538137, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 21462; Mature: 21331

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTVEFYFDVGSPASYLAWTQLPVLCAQAGAQLVYKPMLLGGVFQATGNASPAAVPAKG
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RYVSHDLARFARRYGVPLARNPHFPIITLMLMRAATAVQLREPERFDHFLSTVFQAIWVD
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SLNLNDMGLTAQTLARGGFDAGQIEAWVSDPEIKAALKATTDEALQRGVFGAPTMFVGQE
CCCCCCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MFFGQDRLDFVQEALG
HHCCCHHHHHHHHHHC
>Mature Secondary Structure 
TKTVEFYFDVGSPASYLAWTQLPVLCAQAGAQLVYKPMLLGGVFQATGNASPAAVPAKG
CCEEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RYVSHDLARFARRYGVPLARNPHFPIITLMLMRAATAVQLREPERFDHFLSTVFQAIWVD
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SLNLNDMGLTAQTLARGGFDAGQIEAWVSDPEIKAALKATTDEALQRGVFGAPTMFVGQE
CCCCCCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MFFGQDRLDFVQEALG
HHCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]