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The map label for this gene is nahR [H]

Identifier: 73538543

GI number: 73538543

Start: 1419284

End: 1420186

Strand: Reverse

Name: nahR [H]

Synonym: Reut_B4718

Alternate gene names: 73538543

Gene position: 1420186-1419284 (Counterclockwise)

Preceding gene: 73538548

Following gene: 73538538

Centisome position: 52.09

GC content: 62.02

Gene sequence:

>903_bases
ATGGAGCTGAGAGACGTCGATCTGAACCTGCTGGTTGTGTTTGAACAGTTGCTGCGGCAGGGCACCGTTTCTGGCGCCGC
CAAGGCCATGAACCTCAGCCAGCCGGCCGTGAGCAATGCACTGGCCCGCTTGCGCACGCTGTTGGGGGATCAGTTATTTG
TGCGAAGCAGCAAGGGGATGCTGCCAACGCCGCTCGCGCTGGAGTTGGCTGAGCCCATCAGCTTTGCGCTGGAGTCACTG
CAGGCGACGCTGAGCCAGAAGCGCAGCTTCGACCCCGAGCACAGCACTCGCGCGTTCCGTGTCGCGATGACCGATATCGG
CGAGGTTCATTTCATTCCGCCCTTGATGGGTGCGCTGGGACAACGCGCACCTGGCGTGACGCTGGCGACCGTGCGCAATA
CGGCGGTGGACCTCGCGGCGGACATGAGTCAGGGGAAGATCGATCTGGCGGTCGGCCATCTTCCTGAACTCGGCAGCGGG
TTCTTTCAACGGCGCCTGTTCCGACAGCGCTATGTTTGCCTGTTCCGCCCCGGGCATGCGCTGGACAAGAAGAAGATCAG
CATGCGGGACTTCGAAGCGGCGGAACACGTGGTGGTGACGGCAGCGGGCACAGGGCACGCCCGGGTTGACGAGCTTCTTG
CCGAAGCGGGCGTGAACCGGCGGGTTCGCCTGCACGTCCCGCATTTCGTGGCGCTGGCGGACATCATCGCCACCACCGAT
CTGGTAGCCACGGTGACCTGGACCTTTGCGGAACGATGTGCCCGGTACTTCGGGCTTAAATATGTCAGTCACCCGTTTGC
GCTGCCCGAGATACAGATCAATCTGTTCTGGCATGCCAGGTACCATCACGACCCGGCAAACCAGTGGCTGCGCAATCAGT
TTGTCGAACTGTTCGCGGATTAG

Upstream 100 bases:

>100_bases
CCGTATTGCTTTCCGTATGCGAAGGATCATGGAGCGCCGTGCAAAATAAACCAATAGAATCCGGTCTATAGTCAATATTC
ACAGAATCAATAAGACTTCC

Downstream 100 bases:

>100_bases
AGATGGAAAAGCGGCAGGCAGCCAGCTGAGACGCTGGCTGGCTGCCGCCCGGGGTTACTCCGTTCCCTTCAGCTCGATCA
GCAGATCCTTCGCCGACACC

Product: regulatory protein LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MELRDVDLNLLVVFEQLLRQGTVSGAAKAMNLSQPAVSNALARLRTLLGDQLFVRSSKGMLPTPLALELAEPISFALESL
QATLSQKRSFDPEHSTRAFRVAMTDIGEVHFIPPLMGALGQRAPGVTLATVRNTAVDLAADMSQGKIDLAVGHLPELGSG
FFQRRLFRQRYVCLFRPGHALDKKKISMRDFEAAEHVVVTAAGTGHARVDELLAEAGVNRRVRLHVPHFVALADIIATTD
LVATVTWTFAERCARYFGLKYVSHPFALPEIQINLFWHARYHHDPANQWLRNQFVELFAD

Sequences:

>Translated_300_residues
MELRDVDLNLLVVFEQLLRQGTVSGAAKAMNLSQPAVSNALARLRTLLGDQLFVRSSKGMLPTPLALELAEPISFALESL
QATLSQKRSFDPEHSTRAFRVAMTDIGEVHFIPPLMGALGQRAPGVTLATVRNTAVDLAADMSQGKIDLAVGHLPELGSG
FFQRRLFRQRYVCLFRPGHALDKKKISMRDFEAAEHVVVTAAGTGHARVDELLAEAGVNRRVRLHVPHFVALADIIATTD
LVATVTWTFAERCARYFGLKYVSHPFALPEIQINLFWHARYHHDPANQWLRNQFVELFAD
>Mature_300_residues
MELRDVDLNLLVVFEQLLRQGTVSGAAKAMNLSQPAVSNALARLRTLLGDQLFVRSSKGMLPTPLALELAEPISFALESL
QATLSQKRSFDPEHSTRAFRVAMTDIGEVHFIPPLMGALGQRAPGVTLATVRNTAVDLAADMSQGKIDLAVGHLPELGSG
FFQRRLFRQRYVCLFRPGHALDKKKISMRDFEAAEHVVVTAAGTGHARVDELLAEAGVNRRVRLHVPHFVALADIIATTD
LVATVTWTFAERCARYFGLKYVSHPFALPEIQINLFWHARYHHDPANQWLRNQFVELFAD

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081766, Length=277, Percent_Identity=26.7148014440433, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081684, Length=303, Percent_Identity=26.7326732673267, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790147, Length=308, Percent_Identity=24.6753246753247, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786820, Length=298, Percent_Identity=22.4832214765101, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787601, Length=243, Percent_Identity=22.6337448559671, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789204, Length=218, Percent_Identity=26.605504587156, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=204, Percent_Identity=28.921568627451, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33371; Mature: 33371

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRDVDLNLLVVFEQLLRQGTVSGAAKAMNLSQPAVSNALARLRTLLGDQLFVRSSKGM
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCC
LPTPLALELAEPISFALESLQATLSQKRSFDPEHSTRAFRVAMTDIGEVHFIPPLMGALG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHC
QRAPGVTLATVRNTAVDLAADMSQGKIDLAVGHLPELGSGFFQRRLFRQRYVCLFRPGHA
CCCCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCEEEECCCCC
LDKKKISMRDFEAAEHVVVTAAGTGHARVDELLAEAGVNRRVRLHVPHFVALADIIATTD
CCCHHCCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHH
LVATVTWTFAERCARYFGLKYVSHPFALPEIQINLFWHARYHHDPANQWLRNQFVELFAD
HHHHHHHHHHHHHHHHHCHHHHCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELRDVDLNLLVVFEQLLRQGTVSGAAKAMNLSQPAVSNALARLRTLLGDQLFVRSSKGM
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCC
LPTPLALELAEPISFALESLQATLSQKRSFDPEHSTRAFRVAMTDIGEVHFIPPLMGALG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHC
QRAPGVTLATVRNTAVDLAADMSQGKIDLAVGHLPELGSGFFQRRLFRQRYVCLFRPGHA
CCCCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCEEEECCCCC
LDKKKISMRDFEAAEHVVVTAAGTGHARVDELLAEAGVNRRVRLHVPHFVALADIIATTD
CCCHHCCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHH
LVATVTWTFAERCARYFGLKYVSHPFALPEIQINLFWHARYHHDPANQWLRNQFVELFAD
HHHHHHHHHHHHHHHHHCHHHHCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]