The gene/protein map for NC_007348 is currently unavailable.
Definition Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession NC_007348
Length 2,726,152

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The map label for this gene is livF [H]

Identifier: 73537616

GI number: 73537616

Start: 382108

End: 382845

Strand: Reverse

Name: livF [H]

Synonym: Reut_B3781

Alternate gene names: 73537616

Gene position: 382845-382108 (Counterclockwise)

Preceding gene: 73537617

Following gene: 73537615

Centisome position: 14.04

GC content: 65.31

Gene sequence:

>738_bases
ATGACCCAGGCCACGATACCTGCACTGGAAATCCGCGACCTCCACGCCTGGTACGGCGAATCGCACATCCTGCATGGCGT
TGATCTCACGGTGAATGCCGGCGAGGTCGTCACGCTGCTGGGCCGCAACGGCGCGGGCCGCACCACTACCCTGCGCGCGA
TCATGGGCCTGGTGGGCCAGCGCAAGGGCTCGGTGCGCGTGCATGGCCAGGAGACCGTCACGATGAAGACGCACCGCATC
GCGCCGCTCGGACTCGGCTACTGCCCGGAAGAGCGCGCCATCTTCTCGAGCCTGTCTTGCGAGGAAAACCTGCTCCTGCC
GCCCGAGTTCCCGCGCTCGGCCGGCGCAGTTGGCCTGCGCGAGCCCATGACAGTCGGCGAAATCTACGAGATGTTCCCGA
ACCTGCTCGAACGGCGTAAGAGCCAGGGCACGCGTATGTCGGGCGGGGAGCAGCAGATGCTGGCGGTCGCGCGGATCCTG
CGCACGGGCGCTAGCGTACTGCTACTCGATGAAATCTCGGAGGGCCTCGCGCCGGTCATCGTGCAGAAGCTCGCGAAGAT
GATCACCATGCTGCGCCGGCGCGGCTACACCATCGTGATGGTCGAACAGAACTTCCGCTTCGCCGCGCCGCTGGCTGACC
GCTTCTATGTGATGGAGCACGGCGCCATTGTGGAGGCATTCGAATCGGCGGAGCTGGAACGCAAGATGCCGACGCTTAAC
GCACTGCTCGGCGTGTAA

Upstream 100 bases:

>100_bases
AAGGCAGCTATCAGGAAGTCTCGAACGACCCTCAGGTGAAAGAAGCGTATATGGGAACCACCGACGAGGCCGACGACCTT
CACGTCCGTGCGGAGGCCGC

Downstream 100 bases:

>100_bases
GGAGATTTGCCAATGGAATTGTTCGGAGTGCCCCTGCCGGCGCTGCTTAGTCAGCTCTTGCTGGGACTGGTGAACGGGTC
GTTCTACGCGATCCTGAGTC

Product: ABC transporter-like protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTQATIPALEIRDLHAWYGESHILHGVDLTVNAGEVVTLLGRNGAGRTTTLRAIMGLVGQRKGSVRVHGQETVTMKTHRI
APLGLGYCPEERAIFSSLSCEENLLLPPEFPRSAGAVGLREPMTVGEIYEMFPNLLERRKSQGTRMSGGEQQMLAVARIL
RTGASVLLLDEISEGLAPVIVQKLAKMITMLRRRGYTIVMVEQNFRFAAPLADRFYVMEHGAIVEAFESAELERKMPTLN
ALLGV

Sequences:

>Translated_245_residues
MTQATIPALEIRDLHAWYGESHILHGVDLTVNAGEVVTLLGRNGAGRTTTLRAIMGLVGQRKGSVRVHGQETVTMKTHRI
APLGLGYCPEERAIFSSLSCEENLLLPPEFPRSAGAVGLREPMTVGEIYEMFPNLLERRKSQGTRMSGGEQQMLAVARIL
RTGASVLLLDEISEGLAPVIVQKLAKMITMLRRRGYTIVMVEQNFRFAAPLADRFYVMEHGAIVEAFESAELERKMPTLN
ALLGV
>Mature_244_residues
TQATIPALEIRDLHAWYGESHILHGVDLTVNAGEVVTLLGRNGAGRTTTLRAIMGLVGQRKGSVRVHGQETVTMKTHRIA
PLGLGYCPEERAIFSSLSCEENLLLPPEFPRSAGAVGLREPMTVGEIYEMFPNLLERRKSQGTRMSGGEQQMLAVARILR
TGASVLLLDEISEGLAPVIVQKLAKMITMLRRRGYTIVMVEQNFRFAAPLADRFYVMEHGAIVEAFESAELERKMPTLNA
LLGV

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI21536376, Length=219, Percent_Identity=28.7671232876712, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI27881501, Length=242, Percent_Identity=27.6859504132231, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI30795238, Length=242, Percent_Identity=27.6859504132231, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI47078218, Length=201, Percent_Identity=29.8507462686567, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI45446740, Length=201, Percent_Identity=29.8507462686567, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI150417984, Length=224, Percent_Identity=28.125, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI105990541, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4505771, Length=235, Percent_Identity=26.3829787234043, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI9961250, Length=235, Percent_Identity=26.3829787234043, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31657092, Length=214, Percent_Identity=25.2336448598131, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI9961252, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI116734710, Length=209, Percent_Identity=26.7942583732057, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI153792144, Length=202, Percent_Identity=25.2475247524752, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI42741659, Length=247, Percent_Identity=27.5303643724696, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI90421313, Length=190, Percent_Identity=30.5263157894737, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI27477115, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=218, Percent_Identity=40.8256880733945, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1789593, Length=216, Percent_Identity=31.9444444444444, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789672, Length=225, Percent_Identity=28.8888888888889, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788225, Length=233, Percent_Identity=31.3304721030043, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI48995001, Length=220, Percent_Identity=28.1818181818182, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787029, Length=218, Percent_Identity=28.4403669724771, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788761, Length=239, Percent_Identity=28.4518828451883, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787792, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=28.1938325991189, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081791, Length=234, Percent_Identity=28.2051282051282, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789864, Length=255, Percent_Identity=25.0980392156863, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788450, Length=221, Percent_Identity=28.9592760180996, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790525, Length=221, Percent_Identity=26.2443438914027, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787089, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790190, Length=226, Percent_Identity=25.2212389380531, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=27.8301886792453, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786319, Length=225, Percent_Identity=29.3333333333333, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786253, Length=245, Percent_Identity=29.3877551020408, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788897, Length=216, Percent_Identity=25, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786872, Length=226, Percent_Identity=27.8761061946903, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081709, Length=240, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788644, Length=233, Percent_Identity=27.8969957081545, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789991, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=231, Percent_Identity=27.7056277056277, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786703, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790467, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI48994943, Length=236, Percent_Identity=26.271186440678, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081782, Length=239, Percent_Identity=27.1966527196653, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787112, Length=230, Percent_Identity=29.5652173913043, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786698, Length=193, Percent_Identity=25.3886010362694, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789891, Length=246, Percent_Identity=25.609756097561, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789873, Length=210, Percent_Identity=24.2857142857143, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788165, Length=220, Percent_Identity=26.3636363636364, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=207, Percent_Identity=26.5700483091787, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787712, Length=223, Percent_Identity=25.5605381165919, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790534, Length=206, Percent_Identity=27.6699029126214, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788472, Length=243, Percent_Identity=24.2798353909465, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=221, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17510237, Length=212, Percent_Identity=26.4150943396226, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=215, Percent_Identity=28.8372093023256, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71983510, Length=219, Percent_Identity=26.027397260274, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=219, Percent_Identity=26.027397260274, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=219, Percent_Identity=26.027397260274, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=230, Percent_Identity=25.6521739130435, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=230, Percent_Identity=25.6521739130435, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=216, Percent_Identity=23.6111111111111, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=230, Percent_Identity=25.6521739130435, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=231, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=226, Percent_Identity=24.7787610619469, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24648314, Length=217, Percent_Identity=29.4930875576037, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666092, Length=218, Percent_Identity=27.9816513761468, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643674, Length=216, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221512771, Length=233, Percent_Identity=26.6094420600858, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI116007328, Length=216, Percent_Identity=26.3888888888889, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574150, Length=216, Percent_Identity=26.3888888888889, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85725262, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357907, Length=212, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573571, Length=224, Percent_Identity=24.1071428571429, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573573, Length=224, Percent_Identity=24.1071428571429, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221500365, Length=219, Percent_Identity=24.6575342465753, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007184, Length=219, Percent_Identity=24.6575342465753, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26983; Mature: 26852

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTQATIPALEIRDLHAWYGESHILHGVDLTVNAGEVVTLLGRNGAGRTTTLRAIMGLVGQ
CCCCCCCHHHHHHHHHHHCCCEEEECEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCC
RKGSVRVHGQETVTMKTHRIAPLGLGYCPEERAIFSSLSCEENLLLPPEFPRSAGAVGLR
CCCCEEECCCEEEEEEHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
EPMTVGEIYEMFPNLLERRKSQGTRMSGGEQQMLAVARILRTGASVLLLDEISEGLAPVI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCHHHHH
VQKLAKMITMLRRRGYTIVMVEQNFRFAAPLADRFYVMEHGAIVEAFESAELERKMPTLN
HHHHHHHHHHHHHCCCEEEEEECCCEEECCHHHHEEEEECCHHHHHHHHHHHHHHCCHHH
ALLGV
HHHCC
>Mature Secondary Structure 
TQATIPALEIRDLHAWYGESHILHGVDLTVNAGEVVTLLGRNGAGRTTTLRAIMGLVGQ
CCCCCCHHHHHHHHHHHCCCEEEECEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCC
RKGSVRVHGQETVTMKTHRIAPLGLGYCPEERAIFSSLSCEENLLLPPEFPRSAGAVGLR
CCCCEEECCCEEEEEEHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
EPMTVGEIYEMFPNLLERRKSQGTRMSGGEQQMLAVARILRTGASVLLLDEISEGLAPVI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCHHHHH
VQKLAKMITMLRRRGYTIVMVEQNFRFAAPLADRFYVMEHGAIVEAFESAELERKMPTLN
HHHHHHHHHHHHHCCCEEEEEECCCEEECCHHHHEEEEECCHHHHHHHHHHHHHHCCHHH
ALLGV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]