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The map label for this gene is aldH [H]

Identifier: 73537548

GI number: 73537548

Start: 301080

End: 302657

Strand: Reverse

Name: aldH [H]

Synonym: Reut_B3713

Alternate gene names: 73537548

Gene position: 302657-301080 (Counterclockwise)

Preceding gene: 73537549

Following gene: 73537541

Centisome position: 11.1

GC content: 69.71

Gene sequence:

>1578_bases
ATGACGATAACCGGCGAAATGCTGATCGGCGCGAGCGCCGTGCGCGGCAGCAGCGAACCCTTCCACGCGATCAACCCGGC
CACGGGGGAGACGCTCGAGCCCGAATTCCACGCCTCCGGCACCGATGATGTGGCACGCGCTTGCGAACTGGCCGAAGGGG
CGTTCGACACCTTCCGCGCGACGTCGCCTGACCAGCGCGCACGTTTCCTCGAAGCAATCGCCGACCAGATCGAAGCGCTG
GGCGATGCATTGATCGAACGCGCCCACGCCGAAAGTGCGCTGCCCATCGCCCGCCTGCAAGGCGAGCGCGGCCGCACCAC
CGGTCAGTTGCGCCTGTTCGCCAGCGTGCTGCGCGCCGGTCGCTGGCAGACGGCCACGCTCGACAGGGCCCTGCCCGAAC
GCACGCCGCCGCGCCCGGACCTGCGCATGCAGAAGATCGCAATCGGCCCGGTGGCCGTATTCGGCGCCAGCAACTTCCCG
CTGGCGTTCTCCGTGGCTGGCGGCGACACCGCTTCGGCGCTGGCCGCCGGCTGCCCCGTGGTGGCCAAGGCGCATCCCGC
GCATCCAGGCACGTCGGAACTGGTCGGCCGCGCGATCCGCAAGGCCGTTGCCGATGCCGGCCTGCCAGAGGGCGTGTTCT
CGCTGCTGACCGGCGCAGGTCACACCGTCGGTACGGAACTGGTCGCGCACCCAGCCATCCAGGCCGTGGGCTTCACCGGC
TCGCGCAGCGGCGGCCTGGCGCTGATGCAGGTCGCGAGCAACCGCGCGCAGCCGATTCCCGTCTATGCGGAGATGAGCAG
CATCAACCCGGTCTTTCTGCTGCCCGAGGCGCTGTCGGCGCGCGGCGAAGCCATTGCCCGCGAACTGGCCGATTCGCTGG
TGCTCGGCGTGGGACAGTTCTGCACCAACCCCGGCCTGCTGCTCGCCCTCGAAGGCCCGGCGCTCGACAGGTTCCGCGCG
GCGGCCGGCGCCGCAGTGACCGCGAAGCCGGCCGGCACGATGCTGACGCCGGGTATTCAGCGCGCGTTCGAACATGGCAT
CACCAGTCTGTCGGACATCCCCGGTCTCGCCCGCACCGCGACCGGCCAGGCGAGCACAGGCCCGAACCAGGCCTGCGCCG
CAGTATTCGAAACCACGGCGCAGCGCTTTATCGCCGATCCCCGCATGCATGCCGAAGTGTTCGGCCCTTCCACAGTCCTG
GTGGTCTGCCGCGATGGGGAAGACCTGCTCGCCGTCGCGCAGCAATTGGAAGGCCAACTGACCGCCACCGTGCAAGCAGA
CCGTGGCGACTACGCGCTGGCCGCGCAACTGCTGCCGCTGCTGGAGCGCAAGGTGGGCCGCATCCTGTTCAATGGCTACC
CGACCGGCGTTGAAGTGTCCTACGCCATGGTTCACGGCGGCCCCTTCCCCGCCACGTCCGATACGCGCACGACCTCGGTC
GGCACCACGGCGATGGACCGCTTCCTGCGGCCGGTGTGCTACCAGAACGTGCCCGCGGAACTGCTGCCGCCTGCGTTGCA
GGACGGCAATCCGCTGGACCTGTGGCGCCTGAAGGACGGCCACCCCGCAAAGGGCTGA

Upstream 100 bases:

>100_bases
CGCATGTCATATGATGTCCTATGAGATTCGGCAGCATGCTCAGGCCGATCATTCCGTTTGATGGTGCCCCCGCACCCTTC
TTCTGCAGGAAACCCCAGCC

Downstream 100 bases:

>100_bases
GGGTCTTCAGAACCGGTGGCGCAAACCGACGCTGACGGACCTGGCATCGTCCCCGCTGCCCGGATCGATCGCAATGCTGT
TGTTGGTGACGCTGCCACCG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MTITGEMLIGASAVRGSSEPFHAINPATGETLEPEFHASGTDDVARACELAEGAFDTFRATSPDQRARFLEAIADQIEAL
GDALIERAHAESALPIARLQGERGRTTGQLRLFASVLRAGRWQTATLDRALPERTPPRPDLRMQKIAIGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVAKAHPAHPGTSELVGRAIRKAVADAGLPEGVFSLLTGAGHTVGTELVAHPAIQAVGFTG
SRSGGLALMQVASNRAQPIPVYAEMSSINPVFLLPEALSARGEAIARELADSLVLGVGQFCTNPGLLLALEGPALDRFRA
AAGAAVTAKPAGTMLTPGIQRAFEHGITSLSDIPGLARTATGQASTGPNQACAAVFETTAQRFIADPRMHAEVFGPSTVL
VVCRDGEDLLAVAQQLEGQLTATVQADRGDYALAAQLLPLLERKVGRILFNGYPTGVEVSYAMVHGGPFPATSDTRTTSV
GTTAMDRFLRPVCYQNVPAELLPPALQDGNPLDLWRLKDGHPAKG

Sequences:

>Translated_525_residues
MTITGEMLIGASAVRGSSEPFHAINPATGETLEPEFHASGTDDVARACELAEGAFDTFRATSPDQRARFLEAIADQIEAL
GDALIERAHAESALPIARLQGERGRTTGQLRLFASVLRAGRWQTATLDRALPERTPPRPDLRMQKIAIGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVAKAHPAHPGTSELVGRAIRKAVADAGLPEGVFSLLTGAGHTVGTELVAHPAIQAVGFTG
SRSGGLALMQVASNRAQPIPVYAEMSSINPVFLLPEALSARGEAIARELADSLVLGVGQFCTNPGLLLALEGPALDRFRA
AAGAAVTAKPAGTMLTPGIQRAFEHGITSLSDIPGLARTATGQASTGPNQACAAVFETTAQRFIADPRMHAEVFGPSTVL
VVCRDGEDLLAVAQQLEGQLTATVQADRGDYALAAQLLPLLERKVGRILFNGYPTGVEVSYAMVHGGPFPATSDTRTTSV
GTTAMDRFLRPVCYQNVPAELLPPALQDGNPLDLWRLKDGHPAKG
>Mature_524_residues
TITGEMLIGASAVRGSSEPFHAINPATGETLEPEFHASGTDDVARACELAEGAFDTFRATSPDQRARFLEAIADQIEALG
DALIERAHAESALPIARLQGERGRTTGQLRLFASVLRAGRWQTATLDRALPERTPPRPDLRMQKIAIGPVAVFGASNFPL
AFSVAGGDTASALAAGCPVVAKAHPAHPGTSELVGRAIRKAVADAGLPEGVFSLLTGAGHTVGTELVAHPAIQAVGFTGS
RSGGLALMQVASNRAQPIPVYAEMSSINPVFLLPEALSARGEAIARELADSLVLGVGQFCTNPGLLLALEGPALDRFRAA
AGAAVTAKPAGTMLTPGIQRAFEHGITSLSDIPGLARTATGQASTGPNQACAAVFETTAQRFIADPRMHAEVFGPSTVLV
VCRDGEDLLAVAQQLEGQLTATVQADRGDYALAAQLLPLLERKVGRILFNGYPTGVEVSYAMVHGGPFPATSDTRTTSVG
TTAMDRFLRPVCYQNVPAELLPPALQDGNPLDLWRLKDGHPAKG

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=430, Percent_Identity=25.8139534883721, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI25952152, Length=266, Percent_Identity=27.8195488721804, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI153266822, Length=482, Percent_Identity=25.9336099585062, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87081896, Length=429, Percent_Identity=27.972027972028, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87082295, Length=433, Percent_Identity=25.8660508083141, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787558, Length=479, Percent_Identity=27.9749478079332, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789015, Length=441, Percent_Identity=26.3038548752834, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786504, Length=291, Percent_Identity=29.553264604811, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787684, Length=439, Percent_Identity=25.2847380410023, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081926, Length=450, Percent_Identity=25.5555555555556, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=159, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133930964, Length=268, Percent_Identity=28.7313432835821, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25143876, Length=292, Percent_Identity=23.6301369863014, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25143874, Length=292, Percent_Identity=23.6301369863014, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=462, Percent_Identity=24.8917748917749, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319478, Length=316, Percent_Identity=25.9493670886076, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323821, Length=285, Percent_Identity=27.719298245614, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324950, Length=441, Percent_Identity=22.9024943310658, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362580, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI62472918, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI62472926, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI62472936, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356737, Length=239, Percent_Identity=27.1966527196653, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54713; Mature: 54582

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITGEMLIGASAVRGSSEPFHAINPATGETLEPEFHASGTDDVARACELAEGAFDTFRA
CEEECCHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TSPDQRARFLEAIADQIEALGDALIERAHAESALPIARLQGERGRTTGQLRLFASVLRAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHCC
RWQTATLDRALPERTPPRPDLRMQKIAIGPVAVFGASNFPLAFSVAGGDTASALAAGCPV
CCCHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCCCCCEEEEECCCCHHHHHHHCCCE
VAKAHPAHPGTSELVGRAIRKAVADAGLPEGVFSLLTGAGHTVGTELVAHPAIQAVGFTG
EECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SRSGGLALMQVASNRAQPIPVYAEMSSINPVFLLPEALSARGEAIARELADSLVLGVGQF
CCCCCCHHHHHHCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
CTNPGLLLALEGPALDRFRAAAGAAVTAKPAGTMLTPGIQRAFEHGITSLSDIPGLARTA
HCCCCEEEEECCCCHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCHHCC
TGQASTGPNQACAAVFETTAQRFIADPRMHAEVFGPSTVLVVCRDGEDLLAVAQQLEGQL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCEEEEEEECCHHHHHHHHHHCCCE
TATVQADRGDYALAAQLLPLLERKVGRILFNGYPTGVEVSYAMVHGGPFPATSDTRTTSV
EEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCC
GTTAMDRFLRPVCYQNVPAELLPPALQDGNPLDLWRLKDGHPAKG
CHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TITGEMLIGASAVRGSSEPFHAINPATGETLEPEFHASGTDDVARACELAEGAFDTFRA
EEECCHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TSPDQRARFLEAIADQIEALGDALIERAHAESALPIARLQGERGRTTGQLRLFASVLRAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHCC
RWQTATLDRALPERTPPRPDLRMQKIAIGPVAVFGASNFPLAFSVAGGDTASALAAGCPV
CCCHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCCCCCEEEEECCCCHHHHHHHCCCE
VAKAHPAHPGTSELVGRAIRKAVADAGLPEGVFSLLTGAGHTVGTELVAHPAIQAVGFTG
EECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SRSGGLALMQVASNRAQPIPVYAEMSSINPVFLLPEALSARGEAIARELADSLVLGVGQF
CCCCCCHHHHHHCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
CTNPGLLLALEGPALDRFRAAAGAAVTAKPAGTMLTPGIQRAFEHGITSLSDIPGLARTA
HCCCCEEEEECCCCHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCHHCC
TGQASTGPNQACAAVFETTAQRFIADPRMHAEVFGPSTVLVVCRDGEDLLAVAQQLEGQL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCEEEEEEECCHHHHHHHHHHCCCE
TATVQADRGDYALAAQLLPLLERKVGRILFNGYPTGVEVSYAMVHGGPFPATSDTRTTSV
EEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCC
GTTAMDRFLRPVCYQNVPAELLPPALQDGNPLDLWRLKDGHPAKG
CHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]