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The map label for this gene is pbpG [H]

Identifier: 73537508

GI number: 73537508

Start: 254026

End: 256065

Strand: Reverse

Name: pbpG [H]

Synonym: Reut_B3673

Alternate gene names: 73537508

Gene position: 256065-254026 (Counterclockwise)

Preceding gene: 73537509

Following gene: 73537507

Centisome position: 9.39

GC content: 68.38

Gene sequence:

>2040_bases
ATGAAAAAATTCGCAGTCAAGGCAGGCGGCGCCGCTCTGGCGCTGGCTGCAGCCGGCGTGCTGCTCGCCGGTTTCGCCGC
GGTCGTCAGCCTGCGGCAGCTTCCCCCCGTCGACGCCCTGCGCGAGTACCGGCCGGACGTGCCGCTGCGGATCTTCACGA
GTGACAACGTGCAGATCGGCGAATTCGGCAGCGAGCACCGGGAATTCATCGCGTTCGACAAGATGCCGCGCCAGATGACG
CAGGCATTGCTCGCCGCCGAGGACGACCAGTTCTACGAGCACGACGGCATCGACATCCCCGGCATGTTTCGCGCGGCGCT
GGCCAATCTGGGCAAGGGCTATTCGCAGGGCGCCTCTACCATCACCATGCAGGTGGCGCGCAACTTCTACCTGTCACGCG
AGAAGACGCTTGCGCGCAAGTGGTACGAGATCCTGCTCGCGTGGCAGATCGACCGTACGCTGTCCAAGGACCGCATCCTC
GAGCTGTATATGAACCAGGTCTACCTGGGCGAGCATGCGTACGGTTTCGGCAGCGCGGCCCACGCGTACTTCGGCAAGCC
GCTGGACGGCCTGTCGCTGGCCGAGACCGCGATGCTGGCCGGGCTGCCCAAGGCGCCTTCCACGATGAACCCGGTGGTGA
ACTTCGCGCGCGCCAAGCGCCGGCAGGAGTATGTGCTCGGGCGGATGCTGGCGCTCGGCATGATCAGCCAGGACCAGTAC
CGCGACGCCCGATCGGCGCAGTTGGACATCGCCCCCGACAATGCGGGCCAGTTCGCCGGGCACGCCGAATATGTCGCCGA
ACTCGCGCGCCAGCTTGCGCGCGACCGCTTCGGCGATGAAGCCTACACGCGCGGCCTGAATGTCTACACCACGGTGTCGT
CGGTGCGGCAAACCATGGCCTATGACGCCGTGCGGCGCGGACTGGAAGGCTACGGGAAGCGCCATCGCCTGGCCAGCCCG
GCGGGCGCGCCGCAGGCGGCACTGGTTTCGCTCGATGGCGACACCGGCGCGATCGAGGCCATGGTCGGCGGCGCCGACTT
CGACACCAACCGCTTCAACCATGCGACGCAGGCACTGCGCCAGCCCGGCTCGACGTTCAAGCCGTTCATCTATGCGGCGG
CGCTCGAGCACGGCGTGTCGCCAGGCACGCTGATCAACGACGCGCCGCTCGACAACAACTCGCGCTGGCAGCCGTCCAAC
GACGACGGCCGATTCCTGGGCGCGGTCACGGTGCGCCAAGCGCTGGCCGAGTCGCGCAACCTCCCGGCCATCCGCACGCT
GCAGGCCATCGGCATTCCGTATGCGGTCGAGTTCGCCAGCCGCTTCGGCTTCTCGACCAAGCGGCTGCCGCGCTTCCTGC
CGCTGGCGCTGGGCACCGGCACGACGTCGCCGCTGCGGCTCGCGTCGGCGTATGCGGTGTTTGCCAACCAGGGCCATCGC
GTGGAGCCTTACCTGATCTCGCGCATTACCGACAGCGAAGGCCACGTGCTGTTCGCGGCCGACAATGCCACGGAGCCGCC
GCGCGTCATCAGCGAACGCAATGCCTTCGTGATGGACAGCCTGCTGCGCAGCGTGGTGGACGACGGCACTGGCGCGGGCG
TGCGCCGCTATCTGCACCGCGAGGATGTGGCGGGCAAGACCGGCACCACCAACGACTCGGTCGACGGCTGGTTCGCGGGC
TACGCCGGCAACGTGGTCACGGTGGCCTGGATGGGCTATGACGACAACCATAGCCTGGGCGCCCATGAATTCGGCGCCAC
CACCGCGCTGCCGATCTGGGCTTCGTATATGGAAGGCCGGATGGCAGGCACCCCGGTGGCCGAGCGGGCCGCACCGTCCG
GGGTCGTGCGCAGCAGCGGCGACTGGACGTATGCGGAATATGCCGACGGCAGGCAAGGTATCGCCTCGCTCGGCTTCCCG
GCGCCGCTACCCGCGCCAGCACAGGATGCCGCCGCCACACCGGTAGCCAGCGAAGCCGTTGGCCTGCCCGGCCAGCCCGC
AGCACCGGCCGCGAGCCGCGACGACAGGGCAAGCCTGTAG

Upstream 100 bases:

>100_bases
CAGCATGATCCGCTGCCGGACACACCGCGCACGGCTCCGACAGACCATGACGAGTCCGGTGTGCCTCTGCCGCTGCCCCG
GTTCCGCTAGAATTGCGCGC

Downstream 100 bases:

>100_bases
TCAAGCATCTGGGCTGCAGCGCCCTCCTTTCAACCTCTCAACAACAAGAACCACAATGTCGAGCGTCAGCGCGGTATTGA
TCTGGGCAATTGCTGCCCTC

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MKKFAVKAGGAALALAAAGVLLAGFAAVVSLRQLPPVDALREYRPDVPLRIFTSDNVQIGEFGSEHREFIAFDKMPRQMT
QALLAAEDDQFYEHDGIDIPGMFRAALANLGKGYSQGASTITMQVARNFYLSREKTLARKWYEILLAWQIDRTLSKDRIL
ELYMNQVYLGEHAYGFGSAAHAYFGKPLDGLSLAETAMLAGLPKAPSTMNPVVNFARAKRRQEYVLGRMLALGMISQDQY
RDARSAQLDIAPDNAGQFAGHAEYVAELARQLARDRFGDEAYTRGLNVYTTVSSVRQTMAYDAVRRGLEGYGKRHRLASP
AGAPQAALVSLDGDTGAIEAMVGGADFDTNRFNHATQALRQPGSTFKPFIYAAALEHGVSPGTLINDAPLDNNSRWQPSN
DDGRFLGAVTVRQALAESRNLPAIRTLQAIGIPYAVEFASRFGFSTKRLPRFLPLALGTGTTSPLRLASAYAVFANQGHR
VEPYLISRITDSEGHVLFAADNATEPPRVISERNAFVMDSLLRSVVDDGTGAGVRRYLHREDVAGKTGTTNDSVDGWFAG
YAGNVVTVAWMGYDDNHSLGAHEFGATTALPIWASYMEGRMAGTPVAERAAPSGVVRSSGDWTYAEYADGRQGIASLGFP
APLPAPAQDAAATPVASEAVGLPGQPAAPAASRDDRASL

Sequences:

>Translated_679_residues
MKKFAVKAGGAALALAAAGVLLAGFAAVVSLRQLPPVDALREYRPDVPLRIFTSDNVQIGEFGSEHREFIAFDKMPRQMT
QALLAAEDDQFYEHDGIDIPGMFRAALANLGKGYSQGASTITMQVARNFYLSREKTLARKWYEILLAWQIDRTLSKDRIL
ELYMNQVYLGEHAYGFGSAAHAYFGKPLDGLSLAETAMLAGLPKAPSTMNPVVNFARAKRRQEYVLGRMLALGMISQDQY
RDARSAQLDIAPDNAGQFAGHAEYVAELARQLARDRFGDEAYTRGLNVYTTVSSVRQTMAYDAVRRGLEGYGKRHRLASP
AGAPQAALVSLDGDTGAIEAMVGGADFDTNRFNHATQALRQPGSTFKPFIYAAALEHGVSPGTLINDAPLDNNSRWQPSN
DDGRFLGAVTVRQALAESRNLPAIRTLQAIGIPYAVEFASRFGFSTKRLPRFLPLALGTGTTSPLRLASAYAVFANQGHR
VEPYLISRITDSEGHVLFAADNATEPPRVISERNAFVMDSLLRSVVDDGTGAGVRRYLHREDVAGKTGTTNDSVDGWFAG
YAGNVVTVAWMGYDDNHSLGAHEFGATTALPIWASYMEGRMAGTPVAERAAPSGVVRSSGDWTYAEYADGRQGIASLGFP
APLPAPAQDAAATPVASEAVGLPGQPAAPAASRDDRASL
>Mature_679_residues
MKKFAVKAGGAALALAAAGVLLAGFAAVVSLRQLPPVDALREYRPDVPLRIFTSDNVQIGEFGSEHREFIAFDKMPRQMT
QALLAAEDDQFYEHDGIDIPGMFRAALANLGKGYSQGASTITMQVARNFYLSREKTLARKWYEILLAWQIDRTLSKDRIL
ELYMNQVYLGEHAYGFGSAAHAYFGKPLDGLSLAETAMLAGLPKAPSTMNPVVNFARAKRRQEYVLGRMLALGMISQDQY
RDARSAQLDIAPDNAGQFAGHAEYVAELARQLARDRFGDEAYTRGLNVYTTVSSVRQTMAYDAVRRGLEGYGKRHRLASP
AGAPQAALVSLDGDTGAIEAMVGGADFDTNRFNHATQALRQPGSTFKPFIYAAALEHGVSPGTLINDAPLDNNSRWQPSN
DDGRFLGAVTVRQALAESRNLPAIRTLQAIGIPYAVEFASRFGFSTKRLPRFLPLALGTGTTSPLRLASAYAVFANQGHR
VEPYLISRITDSEGHVLFAADNATEPPRVISERNAFVMDSLLRSVVDDGTGAGVRRYLHREDVAGKTGTTNDSVDGWFAG
YAGNVVTVAWMGYDDNHSLGAHEFGATTALPIWASYMEGRMAGTPVAERAAPSGVVRSSGDWTYAEYADGRQGIASLGFP
APLPAPAQDAAATPVASEAVGLPGQPAAPAASRDDRASL

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=547, Percent_Identity=34.5521023765996, Blast_Score=265, Evalue=9e-72,
Organism=Escherichia coli, GI87082258, Length=367, Percent_Identity=40.8719346049046, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1788867, Length=638, Percent_Identity=28.8401253918495, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1789601, Length=169, Percent_Identity=33.1360946745562, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 73151; Mature: 73151

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFAVKAGGAALALAAAGVLLAGFAAVVSLRQLPPVDALREYRPDVPLRIFTSDNVQIG
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCEEEC
EFGSEHREFIAFDKMPRQMTQALLAAEDDQFYEHDGIDIPGMFRAALANLGKGYSQGAST
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCHH
ITMQVARNFYLSREKTLARKWYEILLAWQIDRTLSKDRILELYMNQVYLGEHAYGFGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HAYFGKPLDGLSLAETAMLAGLPKAPSTMNPVVNFARAKRRQEYVLGRMLALGMISQDQY
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RDARSAQLDIAPDNAGQFAGHAEYVAELARQLARDRFGDEAYTRGLNVYTTVSSVRQTMA
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHH
YDAVRRGLEGYGKRHRLASPAGAPQAALVSLDGDTGAIEAMVGGADFDTNRFNHATQALR
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHH
QPGSTFKPFIYAAALEHGVSPGTLINDAPLDNNSRWQPSNDDGRFLGAVTVRQALAESRN
CCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
LPAIRTLQAIGIPYAVEFASRFGFSTKRLPRFLPLALGTGTTSPLRLASAYAVFANQGHR
CCHHHHHHHHCCCHHHHHHHHCCCCHHHCHHHHHHEECCCCCCHHHHHHHHHHHHCCCCC
VEPYLISRITDSEGHVLFAADNATEPPRVISERNAFVMDSLLRSVVDDGTGAGVRRYLHR
CCHHHEEEEECCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
EDVAGKTGTTNDSVDGWFAGYAGNVVTVAWMGYDDNHSLGAHEFGATTALPIWASYMEGR
HHCCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHCCC
MAGTPVAERAAPSGVVRSSGDWTYAEYADGRQGIASLGFPAPLPAPAQDAAATPVASEAV
CCCCCHHHHCCCCCCEECCCCEEEHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHC
GLPGQPAAPAASRDDRASL
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKFAVKAGGAALALAAAGVLLAGFAAVVSLRQLPPVDALREYRPDVPLRIFTSDNVQIG
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCEEEC
EFGSEHREFIAFDKMPRQMTQALLAAEDDQFYEHDGIDIPGMFRAALANLGKGYSQGAST
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCHH
ITMQVARNFYLSREKTLARKWYEILLAWQIDRTLSKDRILELYMNQVYLGEHAYGFGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HAYFGKPLDGLSLAETAMLAGLPKAPSTMNPVVNFARAKRRQEYVLGRMLALGMISQDQY
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RDARSAQLDIAPDNAGQFAGHAEYVAELARQLARDRFGDEAYTRGLNVYTTVSSVRQTMA
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHH
YDAVRRGLEGYGKRHRLASPAGAPQAALVSLDGDTGAIEAMVGGADFDTNRFNHATQALR
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHH
QPGSTFKPFIYAAALEHGVSPGTLINDAPLDNNSRWQPSNDDGRFLGAVTVRQALAESRN
CCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
LPAIRTLQAIGIPYAVEFASRFGFSTKRLPRFLPLALGTGTTSPLRLASAYAVFANQGHR
CCHHHHHHHHCCCHHHHHHHHCCCCHHHCHHHHHHEECCCCCCHHHHHHHHHHHHCCCCC
VEPYLISRITDSEGHVLFAADNATEPPRVISERNAFVMDSLLRSVVDDGTGAGVRRYLHR
CCHHHEEEEECCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
EDVAGKTGTTNDSVDGWFAGYAGNVVTVAWMGYDDNHSLGAHEFGATTALPIWASYMEGR
HHCCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHCCC
MAGTPVAERAAPSGVVRSSGDWTYAEYADGRQGIASLGFPAPLPAPAQDAAATPVASEAV
CCCCCHHHHCCCCCCEECCCCEEEHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHC
GLPGQPAAPAASRDDRASL
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]