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The map label for this gene is phcA [H]

Identifier: 73537455

GI number: 73537455

Start: 189571

End: 190527

Strand: Reverse

Name: phcA [H]

Synonym: Reut_B3620

Alternate gene names: 73537455

Gene position: 190527-189571 (Counterclockwise)

Preceding gene: 73537460

Following gene: 73537454

Centisome position: 6.99

GC content: 65.52

Gene sequence:

>957_bases
ATGCGTCATGTCAGCACGAAGTTGTTGCATGTTTTCGTCTTAGTCATGGAGTACCGCGACCTCAGCGCGGTAGCGGCCTG
CACGCAAGGGCGTGTCCCGACGGTCGCCTACAGCCTGGCGCGGCTGCGCGAAATCACGGGCGATCCGCTCTTCGTCAAGC
GCAACGGCACGCTGGAGCCGACGCCGCACGCGCTGCGTCTGGAGCAAACCGCCCGGCAGATCCTGGCGAAATGGAACCAG
CTTGTGCGCCCCAATGACCTGGTCACGGAGAAGAGCCATCAGGGCCGACGCCTGTCGATCGGGTTTTCCTCGTCCATTGG
CGACCCGGTAATCACTGAAATCCTGACCACACTGTGCGAGCGATTCCCGCATGACAGCTTCGTGACGCGGCCCGTCATTG
CCGATGCCACGCTGGCCGAAAGCCTGGACAGTGGCGAACTGGACTGCGCTTTCGTGGTGGATGGCGGCCACAACCCGGCG
AAAGTATTGCCGCACAACATCCTCGCAACGCCGCGCCGGCTCGTCAGCGCAATGCGCGCCGGCAGCGCCGACGATACGGA
AAGCGACTGGATCCTGCTGCAGGAAGACTGCGAAGCCGGTAGTCCGCTGCGCAGCTTCCTTGCGCGGCAGGCGAGCACCC
CGGGACACCGCGAGACCGTGGTGCCATCGTGGCACACACAAATCACGCTGCTGCATTCGGCCGGTGGCATCTGCCCTGTG
CTCGATTTCAACGTGCCCCTGGTCACGCGCGATCGCAAGACGCGCCTGCTCGCGCCCCCGAGCAGCTTCCCGGAATGGGC
CGCCCTGCATTTCTGGGCGCCCGAGCGGGCACGCGACAAGGGCGCGCTGCGCGACATCATGGACGTAGGCAGTGCTGTCC
TACGCGACCCCCTCAAGGCGATCGACAACCGCCGCAAGGTCCGGCAGGAACCGCCTCGGCACGCTGCAGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCGCTCGCCCTCGGGCTGCATATCGCCGTCGCATTGCCGGGCAATTGAACACAAGAAAAAACAAAAACAGAAGTCC
ATGGATCGGGAGAAGTCAGA

Downstream 100 bases:

>100_bases
GCCGCGGCAAGCGGGCAGTTCGCCCTCTTAGCCACTTCGATCGATTGCGGTAGCGCAAGCGTTAGTCACGCATATTCCGT
GGGGGACGATGCCGTTTCCG

Product: regulatory protein LysR

Products: NA

Alternate protein names: Virulence genes transcriptional regulator phcA [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRHVSTKLLHVFVLVMEYRDLSAVAACTQGRVPTVAYSLARLREITGDPLFVKRNGTLEPTPHALRLEQTARQILAKWNQ
LVRPNDLVTEKSHQGRRLSIGFSSSIGDPVITEILTTLCERFPHDSFVTRPVIADATLAESLDSGELDCAFVVDGGHNPA
KVLPHNILATPRRLVSAMRAGSADDTESDWILLQEDCEAGSPLRSFLARQASTPGHRETVVPSWHTQITLLHSAGGICPV
LDFNVPLVTRDRKTRLLAPPSSFPEWAALHFWAPERARDKGALRDIMDVGSAVLRDPLKAIDNRRKVRQEPPRHAAAA

Sequences:

>Translated_318_residues
MRHVSTKLLHVFVLVMEYRDLSAVAACTQGRVPTVAYSLARLREITGDPLFVKRNGTLEPTPHALRLEQTARQILAKWNQ
LVRPNDLVTEKSHQGRRLSIGFSSSIGDPVITEILTTLCERFPHDSFVTRPVIADATLAESLDSGELDCAFVVDGGHNPA
KVLPHNILATPRRLVSAMRAGSADDTESDWILLQEDCEAGSPLRSFLARQASTPGHRETVVPSWHTQITLLHSAGGICPV
LDFNVPLVTRDRKTRLLAPPSSFPEWAALHFWAPERARDKGALRDIMDVGSAVLRDPLKAIDNRRKVRQEPPRHAAAA
>Mature_318_residues
MRHVSTKLLHVFVLVMEYRDLSAVAACTQGRVPTVAYSLARLREITGDPLFVKRNGTLEPTPHALRLEQTARQILAKWNQ
LVRPNDLVTEKSHQGRRLSIGFSSSIGDPVITEILTTLCERFPHDSFVTRPVIADATLAESLDSGELDCAFVVDGGHNPA
KVLPHNILATPRRLVSAMRAGSADDTESDWILLQEDCEAGSPLRSFLARQASTPGHRETVVPSWHTQITLLHSAGGICPV
LDFNVPLVTRDRKTRLLAPPSSFPEWAALHFWAPERARDKGALRDIMDVGSAVLRDPLKAIDNRRKVRQEPPRHAAAA

Specific function: Regulates the transcription of one or more of the genes involved in virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35147; Mature: 35147

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVSTKLLHVFVLVMEYRDLSAVAACTQGRVPTVAYSLARLREITGDPLFVKRNGTLEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCC
TPHALRLEQTARQILAKWNQLVRPNDLVTEKSHQGRRLSIGFSSSIGDPVITEILTTLCE
CCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
RFPHDSFVTRPVIADATLAESLDSGELDCAFVVDGGHNPAKVLPHNILATPRRLVSAMRA
HCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCHHHHCCHHHHHHHHHC
GSADDTESDWILLQEDCEAGSPLRSFLARQASTPGHRETVVPSWHTQITLLHSAGGICPV
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEE
LDFNVPLVTRDRKTRLLAPPSSFPEWAALHFWAPERARDKGALRDIMDVGSAVLRDPLKA
EECCCCEEECCCCCEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IDNRRKVRQEPPRHAAAA
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRHVSTKLLHVFVLVMEYRDLSAVAACTQGRVPTVAYSLARLREITGDPLFVKRNGTLEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCC
TPHALRLEQTARQILAKWNQLVRPNDLVTEKSHQGRRLSIGFSSSIGDPVITEILTTLCE
CCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
RFPHDSFVTRPVIADATLAESLDSGELDCAFVVDGGHNPAKVLPHNILATPRRLVSAMRA
HCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCHHHHCCHHHHHHHHHC
GSADDTESDWILLQEDCEAGSPLRSFLARQASTPGHRETVVPSWHTQITLLHSAGGICPV
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCEE
LDFNVPLVTRDRKTRLLAPPSSFPEWAALHFWAPERARDKGALRDIMDVGSAVLRDPLKA
EECCCCEEECCCCCEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IDNRRKVRQEPPRHAAAA
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8366033; 10913109; 11823852 [H]