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The map label for this gene is btr [H]

Identifier: 73537460

GI number: 73537460

Start: 194575

End: 195351

Strand: Reverse

Name: btr [H]

Synonym: Reut_B3625

Alternate gene names: 73537460

Gene position: 195351-194575 (Counterclockwise)

Preceding gene: 73537462

Following gene: 73537455

Centisome position: 7.17

GC content: 68.6

Gene sequence:

>777_bases
ATGTCGGATCCCGCCTCGCCCTCTTGCTCCTTGTGCCTGTTCCGCCACGTCTGCCGTCATGCCCCGGCGGCCGGCACACG
GCCCGACGCCGAGAAACCGCTGCAACCGGCGCACCTGATCGTGCCGGCAGGGGATGCTATTTTTCGCCAGGGCCGGCCCG
TGACAGCGGTGTTTCCGCTTCGGCAAGGCAGCGCCAAGCAGGTCTATGAATCGCCACTGGGCTGGCGGCAGGTGACGGGC
TTTTCGCTGTCCGGAGACGTCCTCGGGCTCGAACCAAATGAGGCGCCGGCGCACAGCGTGAGCGCCCTCGCCTTGCAGGA
CACTGAGTGTTGCGTGGTGCCGGTCGAAGCGCTGCGCGCGCACATGGCCAATGCGGGATTCCGCGATTCGGTGCAGGCAG
TGATGCGCCACCAGGCGGAGCGCGAACGCATTCTGCTCGTCGCAGTGGGCTCGATGAAAGCCGCGCAGCGGCTCGCAATG
CTGCTGCTGGATCTGGACGCCGAACACCGGCGCCGCGGCGGCGCCGATAGCGCGCTCACGCTGGCCATGTCGCGGACCGA
TATCGCCAGCCTGCTCGGCCTGACGCTGGAAACGGTATCGCGCCTGCTGTCGCGTTTCGCCTCGGTGGGTCTGATCTCGG
TGCGTCAGCGTCGCCTGCGGCTGATCGACCGCGACGGCCTGGCTGCCGTCTATGCGGATCTGGACCCGATGCCGCGACCG
GGGCCGGCCACAATCGGCTCGCTGGCCGGGACTGGCAACGAGCCCCGCCCGTTCTAG

Upstream 100 bases:

>100_bases
ATTCAATTAGCCCAATTGAAAGAATACAGATCACGGAGAGATAGCTACCGTTGTTGCGCATTTATACTAGGCTGTCGCCC
CTAGGCGCTCCCACTTCTCC

Downstream 100 bases:

>100_bases
CCGACATCCCAGAGGGCGGCCGGCCTGCCGTCTAGCGTTGAGCTCTACCGTTCAGCGATCCGACACACGCTGCCACCCGT
CCGGGGAGAAGCTCCGGATG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSDPASPSCSLCLFRHVCRHAPAAGTRPDAEKPLQPAHLIVPAGDAIFRQGRPVTAVFPLRQGSAKQVYESPLGWRQVTG
FSLSGDVLGLEPNEAPAHSVSALALQDTECCVVPVEALRAHMANAGFRDSVQAVMRHQAERERILLVAVGSMKAAQRLAM
LLLDLDAEHRRRGGADSALTLAMSRTDIASLLGLTLETVSRLLSRFASVGLISVRQRRLRLIDRDGLAAVYADLDPMPRP
GPATIGSLAGTGNEPRPF

Sequences:

>Translated_258_residues
MSDPASPSCSLCLFRHVCRHAPAAGTRPDAEKPLQPAHLIVPAGDAIFRQGRPVTAVFPLRQGSAKQVYESPLGWRQVTG
FSLSGDVLGLEPNEAPAHSVSALALQDTECCVVPVEALRAHMANAGFRDSVQAVMRHQAERERILLVAVGSMKAAQRLAM
LLLDLDAEHRRRGGADSALTLAMSRTDIASLLGLTLETVSRLLSRFASVGLISVRQRRLRLIDRDGLAAVYADLDPMPRP
GPATIGSLAGTGNEPRPF
>Mature_257_residues
SDPASPSCSLCLFRHVCRHAPAAGTRPDAEKPLQPAHLIVPAGDAIFRQGRPVTAVFPLRQGSAKQVYESPLGWRQVTGF
SLSGDVLGLEPNEAPAHSVSALALQDTECCVVPVEALRAHMANAGFRDSVQAVMRHQAERERILLVAVGSMKAAQRLAML
LLDLDAEHRRRGGADSALTLAMSRTDIASLLGLTLETVSRLLSRFASVGLISVRQRRLRLIDRDGLAAVYADLDPMPRPG
PATIGSLAGTGNEPRPF

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=193, Percent_Identity=29.0155440414508, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27635; Mature: 27504

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPASPSCSLCLFRHVCRHAPAAGTRPDAEKPLQPAHLIVPAGDAIFRQGRPVTAVFPL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCEEEEEEC
RQGSAKQVYESPLGWRQVTGFSLSGDVLGLEPNEAPAHSVSALALQDTECCVVPVEALRA
CCCCHHHHHHCCCCHHHCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCEEEECHHHHHH
HMANAGFRDSVQAVMRHQAERERILLVAVGSMKAAQRLAMLLLDLDAEHRRRGGADSALT
HHHCCCCHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHCCHHHHHCCCCCHHEE
LAMSRTDIASLLGLTLETVSRLLSRFASVGLISVRQRRLRLIDRDGLAAVYADLDPMPRP
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
GPATIGSLAGTGNEPRPF
CCCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
SDPASPSCSLCLFRHVCRHAPAAGTRPDAEKPLQPAHLIVPAGDAIFRQGRPVTAVFPL
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCEEEEEEC
RQGSAKQVYESPLGWRQVTGFSLSGDVLGLEPNEAPAHSVSALALQDTECCVVPVEALRA
CCCCHHHHHHCCCCHHHCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCEEEECHHHHHH
HMANAGFRDSVQAVMRHQAERERILLVAVGSMKAAQRLAMLLLDLDAEHRRRGGADSALT
HHHCCCCHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHCCHHHHHCCCCCHHEE
LAMSRTDIASLLGLTLETVSRLLSRFASVGLISVRQRRLRLIDRDGLAAVYADLDPMPRP
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
GPATIGSLAGTGNEPRPF
CCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]