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The map label for this gene is mmgC [H]

Identifier: 73537392

GI number: 73537392

Start: 110263

End: 111423

Strand: Reverse

Name: mmgC [H]

Synonym: Reut_B3557

Alternate gene names: 73537392

Gene position: 111423-110263 (Counterclockwise)

Preceding gene: 73537393

Following gene: 73537391

Centisome position: 4.09

GC content: 69.34

Gene sequence:

>1161_bases
GTGACCGCACTGCTTTCCACTTTCCAGCTCACCAGCCTGCCGCCGCACGCCATGGCGTTCCGCGAGCAGGTCCGGGCCTT
CCTGGCCGAACAGATGCCGAAGCTGCCGCCCGAAGTCCGCGCACGCTCGTGGATGGGCTTTGACGCTGCCTTCAGCCGCG
CACTCGCCGCGCGCGGCTGGGTCGGGATCACGCTGCCGGCCGGGTACGGCGGTGCCGGCCTGGATCCGTTCTCGCGCTTC
GTGCTGGTCGAAGAACTGCTGGCCGCCGGTGCACCGGTATCGGCCCACTGGATTGCCGACCGCCAGAGCGGTCCGCTGAT
CCTGCGCTACGGCAATGCGGCGCAGAAGGCCAAGTACCTGGCCGCCATCTGCCGCGGCGAAGCGTTCTTCTGCATCGGCA
TGAGCGAGCCCAACTCGGGCTCCGACCTCGCGAGCGTGGCGACGCGTGCCGTGCGGCAAGCGGATGGAACCTGGCTCCTG
AATGGCCGCAAGATCTGGACGACGAACGCGAACCACTGCCACTACATGATTGCGCTGGTCCGCACCTCTGGCACGCCACA
GGACCGGCAGACGGGGTTGTCGCAGGTGATCGTCGACCTTTCGGCACCCGGCGTCACGGTGCGGCCGATCCAGGACCTGA
CTGGCGATGCGCATTTCTCGGAAGTCAGCTTCGAAGACGTGGTGCTGGCGCCCGACGCGCTGGTCGGCCAGGAAGGCAGC
GGCTGGGAACAGGTCAATGCGGAACTCGCCTTCGAGCGCAGCGGCCCGGAGCGGCTGTACTCGAGCGTGGTGCTGCTCGA
TACGTGGCTGGCCGCGCTGCGGCGCCTGCCTGAAGCGCGGCGCGACACCGTCACCGCCGGCCGGCTGGTCGGCCACCTTG
CGGTGCTGCGGTCCATGTCGCTGGCCGTAACGGCGCGCCTGGCCGCCGGCGAAAGCCCGGTGGTCGAAGCCGCGCTGGTT
AAGGATCTCGGCACGACGTTCGAGCAGTCGATCCCGGCGCTTGTCGAAGCCGCGCTCGGCGACGAACCGGCACTCGCGGC
CGATGGCGCGCTGTACCGCACGCTGGCCTATGTCACGCAGATCGCCCCGTCCTATTCGCTGCGCGGCGGCACGCGCGAGA
TCCTGCGCGGCATGATTGCGCGCGGCCTGGGTCTGCGCTGA

Upstream 100 bases:

>100_bases
AGGCCTATGCGAGCTACCTGTCCGCCGAGATGACGCGCTGGCGCAAGGTGGTCAAGGACTCCGGCGCCACGCTCGACTGA
CACGCACCTGGATATTCAAC

Downstream 100 bases:

>100_bases
ACGCGTCCGTTACTGAGTCCACCGCCATGCATAACACCTATTCCGACGCGCTCGACGCCCTGCTGCGCGATCTTTGCCAA
CCTGCCACGGTCCGTGCCAT

Product: acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTALLSTFQLTSLPPHAMAFREQVRAFLAEQMPKLPPEVRARSWMGFDAAFSRALAARGWVGITLPAGYGGAGLDPFSRF
VLVEELLAAGAPVSAHWIADRQSGPLILRYGNAAQKAKYLAAICRGEAFFCIGMSEPNSGSDLASVATRAVRQADGTWLL
NGRKIWTTNANHCHYMIALVRTSGTPQDRQTGLSQVIVDLSAPGVTVRPIQDLTGDAHFSEVSFEDVVLAPDALVGQEGS
GWEQVNAELAFERSGPERLYSSVVLLDTWLAALRRLPEARRDTVTAGRLVGHLAVLRSMSLAVTARLAAGESPVVEAALV
KDLGTTFEQSIPALVEAALGDEPALAADGALYRTLAYVTQIAPSYSLRGGTREILRGMIARGLGLR

Sequences:

>Translated_386_residues
MTALLSTFQLTSLPPHAMAFREQVRAFLAEQMPKLPPEVRARSWMGFDAAFSRALAARGWVGITLPAGYGGAGLDPFSRF
VLVEELLAAGAPVSAHWIADRQSGPLILRYGNAAQKAKYLAAICRGEAFFCIGMSEPNSGSDLASVATRAVRQADGTWLL
NGRKIWTTNANHCHYMIALVRTSGTPQDRQTGLSQVIVDLSAPGVTVRPIQDLTGDAHFSEVSFEDVVLAPDALVGQEGS
GWEQVNAELAFERSGPERLYSSVVLLDTWLAALRRLPEARRDTVTAGRLVGHLAVLRSMSLAVTARLAAGESPVVEAALV
KDLGTTFEQSIPALVEAALGDEPALAADGALYRTLAYVTQIAPSYSLRGGTREILRGMIARGLGLR
>Mature_385_residues
TALLSTFQLTSLPPHAMAFREQVRAFLAEQMPKLPPEVRARSWMGFDAAFSRALAARGWVGITLPAGYGGAGLDPFSRFV
LVEELLAAGAPVSAHWIADRQSGPLILRYGNAAQKAKYLAAICRGEAFFCIGMSEPNSGSDLASVATRAVRQADGTWLLN
GRKIWTTNANHCHYMIALVRTSGTPQDRQTGLSQVIVDLSAPGVTVRPIQDLTGDAHFSEVSFEDVVLAPDALVGQEGSG
WEQVNAELAFERSGPERLYSSVVLLDTWLAALRRLPEARRDTVTAGRLVGHLAVLRSMSLAVTARLAAGESPVVEAALVK
DLGTTFEQSIPALVEAALGDEPALAADGALYRTLAYVTQIAPSYSLRGGTREILRGMIARGLGLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=388, Percent_Identity=26.0309278350515, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=27.3775216138329, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4557233, Length=257, Percent_Identity=26.8482490272374, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501859, Length=238, Percent_Identity=27.7310924369748, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI21361497, Length=240, Percent_Identity=27.5, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=23.5142118863049, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7656849, Length=192, Percent_Identity=28.6458333333333, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI211971008, Length=283, Percent_Identity=27.9151943462898, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI48976061, Length=283, Percent_Identity=27.9151943462898, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4557231, Length=339, Percent_Identity=24.7787610619469, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557235, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI76496475, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI187960098, Length=340, Percent_Identity=25.5882352941176, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38505218, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4503943, Length=164, Percent_Identity=31.0975609756098, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7669494, Length=164, Percent_Identity=31.0975609756098, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=205, Percent_Identity=29.2682926829268, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786223, Length=281, Percent_Identity=25.9786476868327, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=246, Percent_Identity=28.8617886178862, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=235, Percent_Identity=30.2127659574468, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=188, Percent_Identity=32.4468085106383, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=254, Percent_Identity=27.5590551181102, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=225, Percent_Identity=29.7777777777778, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=202, Percent_Identity=31.1881188118812, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=202, Percent_Identity=31.1881188118812, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=210, Percent_Identity=28.0952380952381, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=205, Percent_Identity=29.7560975609756, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=191, Percent_Identity=28.7958115183246, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=188, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=244, Percent_Identity=26.6393442622951, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562446, Length=194, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355753, Length=390, Percent_Identity=25.1282051282051, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666513, Length=239, Percent_Identity=28.8702928870293, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281363737, Length=210, Percent_Identity=32.8571428571429, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356377, Length=195, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=192, Percent_Identity=30.2083333333333, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41323; Mature: 41192

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLSTFQLTSLPPHAMAFREQVRAFLAEQMPKLPPEVRARSWMGFDAAFSRALAARGW
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC
VGITLPAGYGGAGLDPFSRFVLVEELLAAGAPVSAHWIADRQSGPLILRYGNAAQKAKYL
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHH
AAICRGEAFFCIGMSEPNSGSDLASVATRAVRQADGTWLLNGRKIWTTNANHCHYMIALV
HHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCEEEEEEE
RTSGTPQDRQTGLSQVIVDLSAPGVTVRPIQDLTGDAHFSEVSFEDVVLAPDALVGQEGS
ECCCCCCHHHHHHHHHHHCCCCCCEEEECHHHCCCCCCCCCCCCCCEEECCCHHCCCCCC
GWEQVNAELAFERSGPERLYSSVVLLDTWLAALRRLPEARRDTVTAGRLVGHLAVLRSMS
CHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LAVTARLAAGESPVVEAALVKDLGTTFEQSIPALVEAALGDEPALAADGALYRTLAYVTQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IAPSYSLRGGTREILRGMIARGLGLR
HCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TALLSTFQLTSLPPHAMAFREQVRAFLAEQMPKLPPEVRARSWMGFDAAFSRALAARGW
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC
VGITLPAGYGGAGLDPFSRFVLVEELLAAGAPVSAHWIADRQSGPLILRYGNAAQKAKYL
EEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHH
AAICRGEAFFCIGMSEPNSGSDLASVATRAVRQADGTWLLNGRKIWTTNANHCHYMIALV
HHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCEEEEEEE
RTSGTPQDRQTGLSQVIVDLSAPGVTVRPIQDLTGDAHFSEVSFEDVVLAPDALVGQEGS
ECCCCCCHHHHHHHHHHHCCCCCCEEEECHHHCCCCCCCCCCCCCCEEECCCHHCCCCCC
GWEQVNAELAFERSGPERLYSSVVLLDTWLAALRRLPEARRDTVTAGRLVGHLAVLRSMS
CHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LAVTARLAAGESPVVEAALVKDLGTTFEQSIPALVEAALGDEPALAADGALYRTLAYVTQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IAPSYSLRGGTREILRGMIARGLGLR
HCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]