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The map label for this gene is rssA [H]

Identifier: 73543118

GI number: 73543118

Start: 3775800

End: 3777293

Strand: Reverse

Name: rssA [H]

Synonym: Reut_A3436

Alternate gene names: 73543118

Gene position: 3777293-3775800 (Counterclockwise)

Preceding gene: 73543119

Following gene: 73543102

Centisome position: 99.23

GC content: 69.68

Gene sequence:

>1494_bases
ATGTGGCTCCGCAAGCTGCGCCACGGCGCGCGGCGCCCGATCCCGCTGTGGCGGCGCGGCAGCCTGCGCCGCCAGTTGCT
TCTGCTGCTGGTGCCCGCGCTGGCGGCCATGATGGCGATCGACACCTGGCTCACCTACGGCACGCTGCGCCATGCCGCCA
ACACCGCGTACGACCGCTCGCTGTATGGCTCGATCCGGGCGATCGACAACGCCATCGGCATGGCTGGCGAAAGCCTCCAG
CTCTCGTTGCCGGACGCCGCCATGGAGATGTTCGAGACCGCGGCGCAGACCCATGTGTACTATCGCGTCTCGCTCGAGCG
CGCGGGCACGGTCGAAACCGTCACCGGTTACGAAGACCTGCCGCTGCCGAAAGGCTCGCTCGCCAACAACCAGCCGCGCT
TCTACGACGATGACGACTACCGTGGCGAGGCCGTACGCATCGCGGCAATGGCACGGCCCGTGTACCGGCCCGATGCGCGC
ATGCGCGTCATCATCCAGGTCGCCGAATCTGCCGAGCCGCGCACGGCGCTGATCGGCACGGTCTGGCGCAGCGCGCTCGC
GCGCGACCTGCTGCTGATCGTGCTGAGCGCAGCAATCCTCGTCGGCGGCGTCACCTACGTGCTGCGCCCGCTGGGACGGG
TACGCGACGATGTGGAGGCGCGTTCGCCCGACGACCTGACGCCGCTCGCCTTCGACCGCGTGCCCATCGAAGTGAGCCCG
CTGGTCGACGCCGTGAACCTGCATGTCGCGCGCTCCGAAGCGATGGCGCAGGCGCAGGCGCAATTCATCGCCGATGCGGC
GCACCAATTGCGCACGCCGCTGGCCATCCTCAAGACGCAGGCGGAATTCGCGCAGCGGCAGTTGTGCGCGGATGGCGACG
ATCCTGCGTCTCGCCAGGCCGCCGGCGAAGCTGTCGGCGGCATCGTCACGCAACTGGAGCAGGCCGCGCGGCTGACCAAC
CAGCTGCTGGCGCTGGCGCGGGTACGCCAACACCATGGCGAAGCGGCCGCGCCAGCTGCCGATACTGCGGATATCTTTGA
TGCGGTCACGGTGGCCGAGCAGGTAGCGCTCGACTACCTGCCGCTCGCGCGCGGCAAGCAGCAGGACTTCGGCTGGGAGC
CGACGCCAGGGCTCAAGCTGCCCGTGCGCGCCGATGCGGCGCTGCTGCGCGAAGCGCTCGCCAACCTTGTCCACAACGCC
ATCCAGTATTCGCCGAAGGGCAGCCGCATCACGCTGTCGGCACGGCGCGTCGACCAGACCGCGTGCCTGATGGTCGAGGA
CGACGGACCGGGCATTCCCGCCGGCGAGCGCGAGAAGGTATTCGCGCGCTTCTACCGGCGCGTGGGCAACACCGAGCCCG
GCTCGGGTCTGGGGCTGGCGATCTCGCGCGAGATGGCGGCGCGCTTCGGCGGCACGGTGACGCTGACCGAAGGATCGCAG
GGGCGGGGCGTCAGGGCGTTGCTGCAACTGCCGGTCAGCGAACAGGACCTGTGA

Upstream 100 bases:

>100_bases
GTGTACCGCCTGCGCAAGAAACTGGCCGGGCATGGCGTGACGATCGTCACGCTGCGTGGCTTCGGCTACCTGCTCGAGCC
TGAGACACCGGCCGCCTGAC

Downstream 100 bases:

>100_bases
CGCGCGCGGACGTCACGGCCCCTTGATTTCACCTTCCTCTCAACCGAACAGCTCTTCCGCCACCGTCGGATGCAGTTGCA
GCGTCGTCTCCAGATGGGAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MWLRKLRHGARRPIPLWRRGSLRRQLLLLLVPALAAMMAIDTWLTYGTLRHAANTAYDRSLYGSIRAIDNAIGMAGESLQ
LSLPDAAMEMFETAAQTHVYYRVSLERAGTVETVTGYEDLPLPKGSLANNQPRFYDDDDYRGEAVRIAAMARPVYRPDAR
MRVIIQVAESAEPRTALIGTVWRSALARDLLLIVLSAAILVGGVTYVLRPLGRVRDDVEARSPDDLTPLAFDRVPIEVSP
LVDAVNLHVARSEAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLCADGDDPASRQAAGEAVGGIVTQLEQAARLTN
QLLALARVRQHHGEAAAPAADTADIFDAVTVAEQVALDYLPLARGKQQDFGWEPTPGLKLPVRADAALLREALANLVHNA
IQYSPKGSRITLSARRVDQTACLMVEDDGPGIPAGEREKVFARFYRRVGNTEPGSGLGLAISREMAARFGGTVTLTEGSQ
GRGVRALLQLPVSEQDL

Sequences:

>Translated_497_residues
MWLRKLRHGARRPIPLWRRGSLRRQLLLLLVPALAAMMAIDTWLTYGTLRHAANTAYDRSLYGSIRAIDNAIGMAGESLQ
LSLPDAAMEMFETAAQTHVYYRVSLERAGTVETVTGYEDLPLPKGSLANNQPRFYDDDDYRGEAVRIAAMARPVYRPDAR
MRVIIQVAESAEPRTALIGTVWRSALARDLLLIVLSAAILVGGVTYVLRPLGRVRDDVEARSPDDLTPLAFDRVPIEVSP
LVDAVNLHVARSEAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLCADGDDPASRQAAGEAVGGIVTQLEQAARLTN
QLLALARVRQHHGEAAAPAADTADIFDAVTVAEQVALDYLPLARGKQQDFGWEPTPGLKLPVRADAALLREALANLVHNA
IQYSPKGSRITLSARRVDQTACLMVEDDGPGIPAGEREKVFARFYRRVGNTEPGSGLGLAISREMAARFGGTVTLTEGSQ
GRGVRALLQLPVSEQDL
>Mature_497_residues
MWLRKLRHGARRPIPLWRRGSLRRQLLLLLVPALAAMMAIDTWLTYGTLRHAANTAYDRSLYGSIRAIDNAIGMAGESLQ
LSLPDAAMEMFETAAQTHVYYRVSLERAGTVETVTGYEDLPLPKGSLANNQPRFYDDDDYRGEAVRIAAMARPVYRPDAR
MRVIIQVAESAEPRTALIGTVWRSALARDLLLIVLSAAILVGGVTYVLRPLGRVRDDVEARSPDDLTPLAFDRVPIEVSP
LVDAVNLHVARSEAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLCADGDDPASRQAAGEAVGGIVTQLEQAARLTN
QLLALARVRQHHGEAAAPAADTADIFDAVTVAEQVALDYLPLARGKQQDFGWEPTPGLKLPVRADAALLREALANLVHNA
IQYSPKGSRITLSARRVDQTACLMVEDDGPGIPAGEREKVFARFYRRVGNTEPGSGLGLAISREMAARFGGTVTLTEGSQ
GRGVRALLQLPVSEQDL

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=307, Percent_Identity=31.9218241042345, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1789403, Length=336, Percent_Identity=31.547619047619, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786783, Length=268, Percent_Identity=32.089552238806, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786600, Length=264, Percent_Identity=31.0606060606061, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788279, Length=321, Percent_Identity=28.6604361370716, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=340, Percent_Identity=29.7058823529412, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=31.140350877193, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787374, Length=361, Percent_Identity=26.5927977839335, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=294, Percent_Identity=27.2108843537415, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=120, Percent_Identity=39.1666666666667, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787894, Length=273, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=257, Percent_Identity=27.2373540856031, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=22.9838709677419, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=259, Percent_Identity=27.7992277992278, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=25.4901960784314, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=25.9615384615385, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54095; Mature: 54095

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLRKLRHGARRPIPLWRRGSLRRQLLLLLVPALAAMMAIDTWLTYGTLRHAANTAYDRS
CCHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGSIRAIDNAIGMAGESLQLSLPDAAMEMFETAAQTHVYYRVSLERAGTVETVTGYEDL
HHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHEEEEEEEECCCCCEEEECCCCCC
PLPKGSLANNQPRFYDDDDYRGEAVRIAAMARPVYRPDARMRVIIQVAESAEPRTALIGT
CCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCCHHEEEEEECCCCCCHHHHHHH
VWRSALARDLLLIVLSAAILVGGVTYVLRPLGRVRDDVEARSPDDLTPLAFDRVPIEVSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHH
LVDAVNLHVARSEAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLCADGDDPASRQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
AGEAVGGIVTQLEQAARLTNQLLALARVRQHHGEAAAPAADTADIFDAVTVAEQVALDYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PLARGKQQDFGWEPTPGLKLPVRADAALLREALANLVHNAIQYSPKGSRITLSARRVDQT
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCE
ACLMVEDDGPGIPAGEREKVFARFYRRVGNTEPGSGLGLAISREMAARFGGTVTLTEGSQ
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCC
GRGVRALLQLPVSEQDL
CCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MWLRKLRHGARRPIPLWRRGSLRRQLLLLLVPALAAMMAIDTWLTYGTLRHAANTAYDRS
CCHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGSIRAIDNAIGMAGESLQLSLPDAAMEMFETAAQTHVYYRVSLERAGTVETVTGYEDL
HHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHEEEEEEEECCCCCEEEECCCCCC
PLPKGSLANNQPRFYDDDDYRGEAVRIAAMARPVYRPDARMRVIIQVAESAEPRTALIGT
CCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCCCCCHHEEEEEECCCCCCHHHHHHH
VWRSALARDLLLIVLSAAILVGGVTYVLRPLGRVRDDVEARSPDDLTPLAFDRVPIEVSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHH
LVDAVNLHVARSEAMAQAQAQFIADAAHQLRTPLAILKTQAEFAQRQLCADGDDPASRQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
AGEAVGGIVTQLEQAARLTNQLLALARVRQHHGEAAAPAADTADIFDAVTVAEQVALDYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PLARGKQQDFGWEPTPGLKLPVRADAALLREALANLVHNAIQYSPKGSRITLSARRVDQT
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCE
ACLMVEDDGPGIPAGEREKVFARFYRRVGNTEPGSGLGLAISREMAARFGGTVTLTEGSQ
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCC
GRGVRALLQLPVSEQDL
CCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA