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The map label for this gene is yccK [H]

Identifier: 73543064

GI number: 73543064

Start: 3703522

End: 3704544

Strand: Reverse

Name: yccK [H]

Synonym: Reut_A3382

Alternate gene names: 73543064

Gene position: 3704544-3703522 (Counterclockwise)

Preceding gene: 73543065

Following gene: 73543063

Centisome position: 97.32

GC content: 65.3

Gene sequence:

>1023_bases
ATGACCGGAAACGCCAACCCCGCTGCGAGCGTTGCAACCCGCCAGCTAGGCAACCATGGCCCCACGGTCTCGGCCATCGG
CCTTGGCTGCATGGGCATGAGCGATTTCTACGGCGCGCATGACGATGCCGAGTCGATCCGCACGATCCACCATGCGCTCG
ATCGCGGCATTACGCTGCTTGATACCGCGGACATCTATGGGCCGCATACCAATGAAGAACTCGTGGGCCGTGCCATCGCC
GGGCGTCGCGAGCAGGTCGTGCTCGCGACCAAATTCGGCATCGTGCGAGATTTGTCGAAACCCGCAGCGCGTGGCGTCAA
TGGCCGCCCCGAATATGTGCGCGCGAGCTGCGAGGCAAGTTTGAAGCGCCTCGGCGTAGAGCACATCGATTTGTACTACC
AGCACCGCGTCGATCCGGAGGTGCCGATCGAGGAAACCGTGGGCGCGATGGCCGAACTCGTGAAGGCCGGCAAGATCCGC
TGGATCGGGCTGTCCGAGGCCGGCGCGCAAACCCTCGAACGCGCGCACAAGGTGCATCCGGTCACGGCCTTGCAGAGCGA
GTATTCGTTGTGGACGCGCGATGTGGATACCGACGGCATCCTCGCTACGTGCGAGCGGCTGGGCATTGGCTTCGTGCCCT
ATAGCCCGCTGGGCCGCGGCTTCCTGACGGGCGCGATCCGCAGCCCCGAGGACTTCGATGCGGACGATTTCCGTCGCACC
AACCCGCGCTTCATGGGCGAAAACTTCGCGCGCAACCTGGCGCTTGTCGACAAGGTGCGCGCACTGGCGGACGCAAAAGG
CTGCACGCCGGCGCAGCTCGCGCTTGCCTGGGTACTGGCGCGCGGTCCGCAGATCGTGCCGATTCCCGGTACGCGCCGCA
TCGCCAATCTGGACGACAACCTCGGCGCGCTGGACGTGCGGCTCGATGCAAAGGAGCTGGCGGATATCGATGCCATTTTC
CCGGCCGGCGCAGCGGCGGGTACGCGCTATGCCGAGCATGTGATGCCGATGCTGGCACGCTGA

Upstream 100 bases:

>100_bases
TGATCCTGCGCGTGGTACCTTGAACCAGTCGCACGCCTCGCAGCGCTTCAAGCTGGCGTGCATTCGTCGCCGCGCGCGAC
GCCAACCGACAGGAGCAAGC

Downstream 100 bases:

>100_bases
TTCGGGTGCAGGGCCTGCCGCATAATGGCGGGTCCTGAACCGACCTGCCGGAGTGTCCGCATGGCCCTGATTCCCCTCGA
TGCCGCCAGCACGGCGGCGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTGNANPAASVATRQLGNHGPTVSAIGLGCMGMSDFYGAHDDAESIRTIHHALDRGITLLDTADIYGPHTNEELVGRAIA
GRREQVVLATKFGIVRDLSKPAARGVNGRPEYVRASCEASLKRLGVEHIDLYYQHRVDPEVPIEETVGAMAELVKAGKIR
WIGLSEAGAQTLERAHKVHPVTALQSEYSLWTRDVDTDGILATCERLGIGFVPYSPLGRGFLTGAIRSPEDFDADDFRRT
NPRFMGENFARNLALVDKVRALADAKGCTPAQLALAWVLARGPQIVPIPGTRRIANLDDNLGALDVRLDAKELADIDAIF
PAGAAAGTRYAEHVMPMLAR

Sequences:

>Translated_340_residues
MTGNANPAASVATRQLGNHGPTVSAIGLGCMGMSDFYGAHDDAESIRTIHHALDRGITLLDTADIYGPHTNEELVGRAIA
GRREQVVLATKFGIVRDLSKPAARGVNGRPEYVRASCEASLKRLGVEHIDLYYQHRVDPEVPIEETVGAMAELVKAGKIR
WIGLSEAGAQTLERAHKVHPVTALQSEYSLWTRDVDTDGILATCERLGIGFVPYSPLGRGFLTGAIRSPEDFDADDFRRT
NPRFMGENFARNLALVDKVRALADAKGCTPAQLALAWVLARGPQIVPIPGTRRIANLDDNLGALDVRLDAKELADIDAIF
PAGAAAGTRYAEHVMPMLAR
>Mature_339_residues
TGNANPAASVATRQLGNHGPTVSAIGLGCMGMSDFYGAHDDAESIRTIHHALDRGITLLDTADIYGPHTNEELVGRAIAG
RREQVVLATKFGIVRDLSKPAARGVNGRPEYVRASCEASLKRLGVEHIDLYYQHRVDPEVPIEETVGAMAELVKAGKIRW
IGLSEAGAQTLERAHKVHPVTALQSEYSLWTRDVDTDGILATCERLGIGFVPYSPLGRGFLTGAIRSPEDFDADDFRRTN
PRFMGENFARNLALVDKVRALADAKGCTPAQLALAWVLARGPQIVPIPGTRRIANLDDNLGALDVRLDAKELADIDAIFP
AGAAAGTRYAEHVMPMLAR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=322, Percent_Identity=28.8819875776398, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4504825, Length=322, Percent_Identity=28.8819875776398, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=27.0769230769231, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI27436966, Length=322, Percent_Identity=27.0186335403727, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436964, Length=322, Percent_Identity=27.0186335403727, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436971, Length=322, Percent_Identity=27.3291925465839, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI223718702, Length=326, Percent_Identity=31.2883435582822, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI41327764, Length=284, Percent_Identity=31.3380281690141, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI41152114, Length=323, Percent_Identity=29.1021671826625, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789375, Length=339, Percent_Identity=33.0383480825959, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081735, Length=337, Percent_Identity=32.3442136498516, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1788070, Length=307, Percent_Identity=33.5504885993485, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=29.042904290429, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787674, Length=308, Percent_Identity=26.6233766233766, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789199, Length=340, Percent_Identity=29.7058823529412, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994888, Length=284, Percent_Identity=27.112676056338, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=27.6162790697674, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325384, Length=309, Percent_Identity=29.7734627831715, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=24.9221183800623, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=22.4832214765101, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=24.5210727969349, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=308, Percent_Identity=23.7012987012987, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24657054, Length=342, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24640980, Length=344, Percent_Identity=24.1279069767442, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45549126, Length=344, Percent_Identity=24.1279069767442, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45553081, Length=329, Percent_Identity=26.7477203647416, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24663317, Length=352, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24646155, Length=157, Percent_Identity=35.031847133758, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281366140, Length=291, Percent_Identity=27.4914089347079, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129731, Length=346, Percent_Identity=25.7225433526012, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=30.0884955752212, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36706; Mature: 36575

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNANPAASVATRQLGNHGPTVSAIGLGCMGMSDFYGAHDDAESIRTIHHALDRGITLL
CCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCEEE
DTADIYGPHTNEELVGRAIAGRREQVVLATKFGIVRDLSKPAARGVNGRPEYVRASCEAS
ECHHCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKRLGVEHIDLYYQHRVDPEVPIEETVGAMAELVKAGKIRWIGLSEAGAQTLERAHKVHP
HHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCC
VTALQSEYSLWTRDVDTDGILATCERLGIGFVPYSPLGRGFLTGAIRSPEDFDADDFRRT
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCC
NPRFMGENFARNLALVDKVRALADAKGCTPAQLALAWVLARGPQIVPIPGTRRIANLDDN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCEECCCCCC
LGALDVRLDAKELADIDAIFPAGAAAGTRYAEHVMPMLAR
CCEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGNANPAASVATRQLGNHGPTVSAIGLGCMGMSDFYGAHDDAESIRTIHHALDRGITLL
CCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCEEE
DTADIYGPHTNEELVGRAIAGRREQVVLATKFGIVRDLSKPAARGVNGRPEYVRASCEAS
ECHHCCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LKRLGVEHIDLYYQHRVDPEVPIEETVGAMAELVKAGKIRWIGLSEAGAQTLERAHKVHP
HHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCC
VTALQSEYSLWTRDVDTDGILATCERLGIGFVPYSPLGRGFLTGAIRSPEDFDADDFRRT
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCC
NPRFMGENFARNLALVDKVRALADAKGCTPAQLALAWVLARGPQIVPIPGTRRIANLDDN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCEECCCCCC
LGALDVRLDAKELADIDAIFPAGAAAGTRYAEHVMPMLAR
CCEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]