Click here to switch to the map view.

The map label for this gene is cfxR [H]

Identifier: 73543055

GI number: 73543055

Start: 3693441

End: 3694328

Strand: Direct

Name: cfxR [H]

Synonym: Reut_A3373

Alternate gene names: 73543055

Gene position: 3693441-3694328 (Clockwise)

Preceding gene: 73543042

Following gene: 73543059

Centisome position: 97.03

GC content: 67.91

Gene sequence:

>888_bases
TTGGATCTCCATCACCTGCGCGCCTTCGTCGCCGTCGCGCGCGAAGGCAATCTGACCCGCGCCGCCCAGCGCCTGCACCT
CACGCAGCCGGCCGTGAGCCTGCAGCTCAAGGCGCTGCAATCGGCATGGCGCGTCCGCGTGTTCGAACGCACCGCCACTG
GCCTCACGCTGACCGCCGATGGCGCCGCCCTGTTGCCGCTCGCCGAGCGCATTCTCGACAGCGTCGGCGACCTGCAGCAC
ACCGTCGATGCAATGCACACCACCGTGCGGGGCAAGCTTGCGATCGGCACCATCCTCGACCCGGAATTCACGCGTCTCGG
CGTCATGCTGCGCGCGCTGGTCGAGCGCCATCCGCAGATCGGCACGGAGTTGCGCCACGGCATGTCGGGCTGGGTGCTGC
AGCAGATACGCAGCGGCGCGCTCGATGTGGGCTTCTACCTCGGGCAGCTGCCGGATGCCGGCTTCCATGCGCTGGCATTG
ACGCCGTTCTCGTATTACGTTGTCGCGCCTAAGGGCTGGAAGGAGCGCACCGCGCTGCGCTCGTGGGCGCAGCTCGCGAC
GCTGCCGTGGATCTGGACGCCGTCCGAATCCGCGCACAACCGGCTGCTGTCGGCGCGCTTTGCCGAAGCGGGCGTCGACG
CGGCCAGCGTGCACAAGGTCGCGCATGTGGACCAGGAAGCATCGATGCTGGACCTGGTGCGCTCGGGTGTCGGCCTGTCG
CTGGTGCGCGACTCGATCGCGCTGCGCGAATCGCACGCGCATGGCCTCGTGGTGGTGGAAGGCATGTCCGTGCAGACGGA
ACTGATGCTTGTCGCGCTGGCCAGCCGACGTGAAGATCCCGTCGTCAGCGCAGTGTTCGGCGTCGCTGAGTCCGTTTTTC
GAACCTAG

Upstream 100 bases:

>100_bases
GCAAGATTGGCGCAGTTGCACGGGCCCGTCCAATGATTTATCGTCAATCGCAATATAAGCCGCGCAAAATATTGCAGCGC
ACACTGAAGCGCCCCGGACC

Downstream 100 bases:

>100_bases
ACTGGCTGCGCCAGATGCCGCCGCAGCCAGTCCGTCAGCGCCGCAAATACCTTGCTGCGCAACGGCTCGGCCTCGTTGAA
GATCTCATGGTAGCCCTCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: RuBisCO operon transcriptional regulator [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDLHHLRAFVAVAREGNLTRAAQRLHLTQPAVSLQLKALQSAWRVRVFERTATGLTLTADGAALLPLAERILDSVGDLQH
TVDAMHTTVRGKLAIGTILDPEFTRLGVMLRALVERHPQIGTELRHGMSGWVLQQIRSGALDVGFYLGQLPDAGFHALAL
TPFSYYVVAPKGWKERTALRSWAQLATLPWIWTPSESAHNRLLSARFAEAGVDAASVHKVAHVDQEASMLDLVRSGVGLS
LVRDSIALRESHAHGLVVVEGMSVQTELMLVALASRREDPVVSAVFGVAESVFRT

Sequences:

>Translated_295_residues
MDLHHLRAFVAVAREGNLTRAAQRLHLTQPAVSLQLKALQSAWRVRVFERTATGLTLTADGAALLPLAERILDSVGDLQH
TVDAMHTTVRGKLAIGTILDPEFTRLGVMLRALVERHPQIGTELRHGMSGWVLQQIRSGALDVGFYLGQLPDAGFHALAL
TPFSYYVVAPKGWKERTALRSWAQLATLPWIWTPSESAHNRLLSARFAEAGVDAASVHKVAHVDQEASMLDLVRSGVGLS
LVRDSIALRESHAHGLVVVEGMSVQTELMLVALASRREDPVVSAVFGVAESVFRT
>Mature_295_residues
MDLHHLRAFVAVAREGNLTRAAQRLHLTQPAVSLQLKALQSAWRVRVFERTATGLTLTADGAALLPLAERILDSVGDLQH
TVDAMHTTVRGKLAIGTILDPEFTRLGVMLRALVERHPQIGTELRHGMSGWVLQQIRSGALDVGFYLGQLPDAGFHALAL
TPFSYYVVAPKGWKERTALRSWAQLATLPWIWTPSESAHNRLLSARFAEAGVDAASVHKVAHVDQEASMLDLVRSGVGLS
LVRDSIALRESHAHGLVVVEGMSVQTELMLVALASRREDPVVSAVFGVAESVFRT

Specific function: Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=24.7967479674797, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367136, Length=254, Percent_Identity=24.0157480314961, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788887, Length=145, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=160, Percent_Identity=32.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=283, Percent_Identity=26.1484098939929, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=158, Percent_Identity=29.1139240506329, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789506, Length=241, Percent_Identity=23.6514522821577, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787806, Length=246, Percent_Identity=23.5772357723577, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081904, Length=74, Percent_Identity=45.945945945946, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32176; Mature: 32176

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50931 HTH_LYSR ; PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHHLRAFVAVAREGNLTRAAQRLHLTQPAVSLQLKALQSAWRVRVFERTATGLTLTAD
CCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCEEEECC
GAALLPLAERILDSVGDLQHTVDAMHTTVRGKLAIGTILDPEFTRLGVMLRALVERHPQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
GTELRHGMSGWVLQQIRSGALDVGFYLGQLPDAGFHALALTPFSYYVVAPKGWKERTALR
CHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHH
SWAQLATLPWIWTPSESAHNRLLSARFAEAGVDAASVHKVAHVDQEASMLDLVRSGVGLS
HHHHHHHCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCHH
LVRDSIALRESHAHGLVVVEGMSVQTELMLVALASRREDPVVSAVFGVAESVFRT
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLHHLRAFVAVAREGNLTRAAQRLHLTQPAVSLQLKALQSAWRVRVFERTATGLTLTAD
CCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCEEEECC
GAALLPLAERILDSVGDLQHTVDAMHTTVRGKLAIGTILDPEFTRLGVMLRALVERHPQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
GTELRHGMSGWVLQQIRSGALDVGFYLGQLPDAGFHALALTPFSYYVVAPKGWKERTALR
CHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHHHHHH
SWAQLATLPWIWTPSESAHNRLLSARFAEAGVDAASVHKVAHVDQEASMLDLVRSGVGLS
HHHHHHHCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCHH
LVRDSIALRESHAHGLVVVEGMSVQTELMLVALASRREDPVVSAVFGVAESVFRT
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1779759 [H]