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The map label for this gene is ompR [H]

Identifier: 73543008

GI number: 73543008

Start: 3634810

End: 3635541

Strand: Reverse

Name: ompR [H]

Synonym: Reut_A3326

Alternate gene names: 73543008

Gene position: 3635541-3634810 (Counterclockwise)

Preceding gene: 73543009

Following gene: 73543007

Centisome position: 95.51

GC content: 66.94

Gene sequence:

>732_bases
ATGGATTTCGCTCCCAACCTGCCGATTCGCCTGCTGGTCGTCGACGACGACCCACAGATCCGCGCCATGCTCGCCGAGTA
CCTGTCCACCTTCGGCATGCAGGCCGACGGCGTCGAGGGCGGTGCACAGATGCGGCGTGCCATGGCCGCCGGCGACTATG
ACATGGTCATCCTCGACCTGTCGCTGCCCGGCGAAAGCGGTCTGGACCTGTGCCGCCAGCTACGCGCGCAGACCGATGTG
GCGGTGATCATGCTGACCGCGCGGGCCGAACTCGCCGATCGCGTTGTCGGGCTTGAAGTGGGAGCGGACGACTATGTCAC
CAAGCCGTTCGAGATGCGTGAGCTCGTGGCCCGCATCCACACGGTGCTGCGCCGCAGCCGCAGTGACACCCGCCGCGCGG
CGGCAACGTCGGGCGGCCATGAGGTGCGTTTCGGCACCTGGCGCCTCAACACGATGCTGCGCCAGCTTGTCGATGGCGAC
GACGTGGTGGTGCCGCTGTCCAATGCCGAATTCCGCCTGCTGCTGACCTTTGTCGAGCATCCGAACCGCGTGCTCGACCG
CGAGCTGCTGATCAACCAGGCGCGTGGTCGCGGCCTTGATGTGTTCGATCGCAGCATCGACCTGCTGGTGTCGCGGCTGC
GCCAGAAGCTGCGCGATGATCCGCGCGACCCCGTACTGATCCGCACTGTGCGCGGCGAAGGCTACGTGTTCACCACGGCG
CCGGAGCGCTGA

Upstream 100 bases:

>100_bases
GCCAAAGGGCCGGCATGCCGAACTGGTAAAGTGGTCGGCCGCTTTACCCTCTGACCGGCACTGTCATCGCCGGCTCGTGC
CTGCATCGCCACACCGCCTC

Downstream 100 bases:

>100_bases
AGCCATGGCCCGCTTCGCGCGCTACGACTCGATGTTCCTGCGGCTGTTCGTGGTCATGGCCACGATCATGCTGTGCGTGC
ACCTGCTCGGCGTGACCGTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDFAPNLPIRLLVVDDDPQIRAMLAEYLSTFGMQADGVEGGAQMRRAMAAGDYDMVILDLSLPGESGLDLCRQLRAQTDV
AVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIHTVLRRSRSDTRRAAATSGGHEVRFGTWRLNTMLRQLVDGD
DVVVPLSNAEFRLLLTFVEHPNRVLDRELLINQARGRGLDVFDRSIDLLVSRLRQKLRDDPRDPVLIRTVRGEGYVFTTA
PER

Sequences:

>Translated_243_residues
MDFAPNLPIRLLVVDDDPQIRAMLAEYLSTFGMQADGVEGGAQMRRAMAAGDYDMVILDLSLPGESGLDLCRQLRAQTDV
AVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIHTVLRRSRSDTRRAAATSGGHEVRFGTWRLNTMLRQLVDGD
DVVVPLSNAEFRLLLTFVEHPNRVLDRELLINQARGRGLDVFDRSIDLLVSRLRQKLRDDPRDPVLIRTVRGEGYVFTTA
PER
>Mature_243_residues
MDFAPNLPIRLLVVDDDPQIRAMLAEYLSTFGMQADGVEGGAQMRRAMAAGDYDMVILDLSLPGESGLDLCRQLRAQTDV
AVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIHTVLRRSRSDTRRAAATSGGHEVRFGTWRLNTMLRQLVDGD
DVVVPLSNAEFRLLLTFVEHPNRVLDRELLINQARGRGLDVFDRSIDLLVSRLRQKLRDDPRDPVLIRTVRGEGYVFTTA
PER

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=44.3478260869565, Blast_Score=190, Evalue=6e-50,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=35.4700854700855, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=37.5, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=37.4468085106383, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.9098712446352, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=37.2294372294372, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=35.6521739130435, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=36.7256637168142, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=32.3404255319149, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=30.7692307692308, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=34.3347639484979, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=34.3612334801762, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=32.3404255319149, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=30.7359307359307, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=35.4545454545455, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27302; Mature: 27302

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFAPNLPIRLLVVDDDPQIRAMLAEYLSTFGMQADGVEGGAQMRRAMAAGDYDMVILDL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
SLPGESGLDLCRQLRAQTDVAVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIH
ECCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHH
TVLRRSRSDTRRAAATSGGHEVRFGTWRLNTMLRQLVDGDDVVVPLSNAEFRLLLTFVEH
HHHHHCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHC
PNRVLDRELLINQARGRGLDVFDRSIDLLVSRLRQKLRDDPRDPVLIRTVRGEGYVFTTA
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECC
PER
CCC
>Mature Secondary Structure
MDFAPNLPIRLLVVDDDPQIRAMLAEYLSTFGMQADGVEGGAQMRRAMAAGDYDMVILDL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
SLPGESGLDLCRQLRAQTDVAVIMLTARAELADRVVGLEVGADDYVTKPFEMRELVARIH
ECCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHH
TVLRRSRSDTRRAAATSGGHEVRFGTWRLNTMLRQLVDGDDVVVPLSNAEFRLLLTFVEH
HHHHHCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHC
PNRVLDRELLINQARGRGLDVFDRSIDLLVSRLRQKLRDDPRDPVLIRTVRGEGYVFTTA
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECC
PER
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]