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The map label for this gene is ttuD [H]

Identifier: 73542977

GI number: 73542977

Start: 3602983

End: 3604290

Strand: Direct

Name: ttuD [H]

Synonym: Reut_A3294

Alternate gene names: 73542977

Gene position: 3602983-3604290 (Clockwise)

Preceding gene: 73542976

Following gene: 73542978

Centisome position: 94.65

GC content: 69.72

Gene sequence:

>1308_bases
ATGCTCGACACCGAAACCAGCGCCGCCCTGCTGACCCCGCAGCGTCCCAGCCTCCAGCCGCGCGCCCTGTTGCGCGACCT
GTTCGATACCGCCGTGGCATCGGTCAGCGCCAGCCACTGCCTGCCGCCGCACCTGCCGCATCCGCCGAAGGGCCGCACCG
TGGTAATCGGCGCCGGCAAGGCCGCCGCCGCGATGGCGCAGGCTGTCGAAGCGCACTGGCAAGGCGAGCTGAGCGGACTG
GTGGTGACGCGCTATGGCCACGGTGCCGACTGCAAGCGCATCGAAGTCGTCGAAGCCGCGCATCCGGTGCCCGATGAAGC
CGGCGCCCGCGCCGCGCAGCGCATGGTCGAACTCGTGCAGGGCCTGACCGCCGACGATCTCGTGCTGTGCCTGATTTCCG
GTGGCGGCTCCGCGTTGCTCGCCGCGCCCGCGCCTGGCATCTCGCTCGCCGACAAGCAGGCCGTCAACAAGGCCCTGCTG
CGCAGCGGCGCGAGCATCGGCGAGATGAACTGCGTGCGCAAGCACCTGTCGGCGCTCAAGGGCGGGCGCCTCGCGTTGCA
CTGCGCACCGGCGCGTGTCGAGACGCTGCTGATTTCCGATATTCCCGGCGATGACCCCACGCTGATCGCGAGCGGCCCGA
CGCTGCCCGACGCAACGACGTGCGCCGACGCGCTCGCGGTCATCGCCAAGTACGGCATCGACGTGCCGGCCAATGTGCGT
GCCCATCTGGAAAGCGGCGCAGGCGAAACGCCGAAGCCCGGCGATGCACGCTTTGCGGGCCACCGCAGCGTGACGCTGGC
CACCGCGCAGCAATCGCTCGAAGCGGCCGCGGCACGTGCGCGCGAACTCGGCTTCGAGGCGCACATCCTGTCCGATTGCA
TCGAAGGCGAAGCGCGCGACGTGGCGCTCGTGCACGCGGCCATCGCACGCCAGATCGCACAGCACGGCCAACCCTTCAGC
AAGCCATGCGTGCTGTTGTCCGGCGGCGAGACCACGGTGACCGTGCGCGGCAAGGGCCGTGGCGGGCGCAATGCGGAATT
CCTGCTGTCGCTGGCCGTTGCGCTCGATGGCCTGCCCGGCGTGCATGCGATTGCTTGCGACACCGACGGCATCGACGGCT
CCGAAGACAACGCCGGCGCGCTGCTCGCGCCGGATACGCTGACCCGCGCCGCCTCACGCGGCTTGTCGGCCCGCGCGCAT
CTGGAAAACAACGACGGCTATGGCTTCTTTGCCGGCGTGGACGACCTGATCGTGACCGGCCCGACCCGCACCAACGTGAA
CGATTTCCGCGCGATCCTTATCGTTTGA

Upstream 100 bases:

>100_bases
AAGCACATCGCTGCACACGCAAGATCTGCAGTACCTGTAGTTGCAGCAAACGCCGTCCCCTTCGCGGGGACGGCCTCAGT
TTCAGTTCCCAGGATTCCCC

Downstream 100 bases:

>100_bases
GTATCGCGTCCGAACTGAACCGCATTACCGGCGCGCCACCACGGCGCGCCGTTCCGAGAATGGAAGAGGAGACATCATGA
GACGCCAGCGCAAAGCCAAG

Product: glycerate 2-kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLDTETSAALLTPQRPSLQPRALLRDLFDTAVASVSASHCLPPHLPHPPKGRTVVIGAGKAAAAMAQAVEAHWQGELSGL
VVTRYGHGADCKRIEVVEAAHPVPDEAGARAAQRMVELVQGLTADDLVLCLISGGGSALLAAPAPGISLADKQAVNKALL
RSGASIGEMNCVRKHLSALKGGRLALHCAPARVETLLISDIPGDDPTLIASGPTLPDATTCADALAVIAKYGIDVPANVR
AHLESGAGETPKPGDARFAGHRSVTLATAQQSLEAAAARARELGFEAHILSDCIEGEARDVALVHAAIARQIAQHGQPFS
KPCVLLSGGETTVTVRGKGRGGRNAEFLLSLAVALDGLPGVHAIACDTDGIDGSEDNAGALLAPDTLTRAASRGLSARAH
LENNDGYGFFAGVDDLIVTGPTRTNVNDFRAILIV

Sequences:

>Translated_435_residues
MLDTETSAALLTPQRPSLQPRALLRDLFDTAVASVSASHCLPPHLPHPPKGRTVVIGAGKAAAAMAQAVEAHWQGELSGL
VVTRYGHGADCKRIEVVEAAHPVPDEAGARAAQRMVELVQGLTADDLVLCLISGGGSALLAAPAPGISLADKQAVNKALL
RSGASIGEMNCVRKHLSALKGGRLALHCAPARVETLLISDIPGDDPTLIASGPTLPDATTCADALAVIAKYGIDVPANVR
AHLESGAGETPKPGDARFAGHRSVTLATAQQSLEAAAARARELGFEAHILSDCIEGEARDVALVHAAIARQIAQHGQPFS
KPCVLLSGGETTVTVRGKGRGGRNAEFLLSLAVALDGLPGVHAIACDTDGIDGSEDNAGALLAPDTLTRAASRGLSARAH
LENNDGYGFFAGVDDLIVTGPTRTNVNDFRAILIV
>Mature_435_residues
MLDTETSAALLTPQRPSLQPRALLRDLFDTAVASVSASHCLPPHLPHPPKGRTVVIGAGKAAAAMAQAVEAHWQGELSGL
VVTRYGHGADCKRIEVVEAAHPVPDEAGARAAQRMVELVQGLTADDLVLCLISGGGSALLAAPAPGISLADKQAVNKALL
RSGASIGEMNCVRKHLSALKGGRLALHCAPARVETLLISDIPGDDPTLIASGPTLPDATTCADALAVIAKYGIDVPANVR
AHLESGAGETPKPGDARFAGHRSVTLATAQQSLEAAAARARELGFEAHILSDCIEGEARDVALVHAAIARQIAQHGQPFS
KPCVLLSGGETTVTVRGKGRGGRNAEFLLSLAVALDGLPGVHAIACDTDGIDGSEDNAGALLAPDTLTRAASRGLSARAH
LENNDGYGFFAGVDDLIVTGPTRTNVNDFRAILIV

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=485, Percent_Identity=32.9896907216495, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193205461, Length=412, Percent_Identity=29.8543689320388, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI19920578, Length=387, Percent_Identity=29.9741602067183, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44730; Mature: 44730

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00134 TRYPSIN_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTETSAALLTPQRPSLQPRALLRDLFDTAVASVSASHCLPPHLPHPPKGRTVVIGAGK
CCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCH
AAAAMAQAVEAHWQGELSGLVVTRYGHGADCKRIEVVEAAHPVPDEAGARAAQRMVELVQ
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHH
GLTADDLVLCLISGGGSALLAAPAPGISLADKQAVNKALLRSGASIGEMNCVRKHLSALK
CCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GGRLALHCAPARVETLLISDIPGDDPTLIASGPTLPDATTCADALAVIAKYGIDVPANVR
CCCEEEEECCCCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
AHLESGAGETPKPGDARFAGHRSVTLATAQQSLEAAAARARELGFEAHILSDCIEGEARD
HHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
VALVHAAIARQIAQHGQPFSKPCVLLSGGETTVTVRGKGRGGRNAEFLLSLAVALDGLPG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCC
VHAIACDTDGIDGSEDNAGALLAPDTLTRAASRGLSARAHLENNDGYGFFAGVDDLIVTG
CEEEEECCCCCCCCCCCCCEEECCHHHHHHHHCCCCEEEEEECCCCCEEEECCCCEEEEC
PTRTNVNDFRAILIV
CCCCCCCCEEEEEEC
>Mature Secondary Structure
MLDTETSAALLTPQRPSLQPRALLRDLFDTAVASVSASHCLPPHLPHPPKGRTVVIGAGK
CCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCH
AAAAMAQAVEAHWQGELSGLVVTRYGHGADCKRIEVVEAAHPVPDEAGARAAQRMVELVQ
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHH
GLTADDLVLCLISGGGSALLAAPAPGISLADKQAVNKALLRSGASIGEMNCVRKHLSALK
CCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GGRLALHCAPARVETLLISDIPGDDPTLIASGPTLPDATTCADALAVIAKYGIDVPANVR
CCCEEEEECCCCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHH
AHLESGAGETPKPGDARFAGHRSVTLATAQQSLEAAAARARELGFEAHILSDCIEGEARD
HHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHH
VALVHAAIARQIAQHGQPFSKPCVLLSGGETTVTVRGKGRGGRNAEFLLSLAVALDGLPG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCC
VHAIACDTDGIDGSEDNAGALLAPDTLTRAASRGLSARAHLENNDGYGFFAGVDDLIVTG
CEEEEECCCCCCCCCCCCCEEECCHHHHHHHHCCCCEEEEEECCCCCEEEECCCCEEEEC
PTRTNVNDFRAILIV
CCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]