| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is paaG [H]
Identifier: 73542965
GI number: 73542965
Start: 3589535
End: 3590320
Strand: Direct
Name: paaG [H]
Synonym: Reut_A3282
Alternate gene names: 73542965
Gene position: 3589535-3590320 (Clockwise)
Preceding gene: 73542964
Following gene: 73542966
Centisome position: 94.3
GC content: 67.94
Gene sequence:
>786_bases ATGACTTCCCCCGTGCTCTACCACGCCAGCGAAGGTGTGGCCACCATCACCCTGAACCGTCCTGAAGTCCTGAACGCACT CAACGCGGAACTGCTGCGTGAACTGCGCGCGGCCGTGGACCGTGCCGCCGCCGATGAATCCGTGCGCGCCGTCGTGCTGA CCGGCGCCGGCCGAGGCTTCTCGTCGGGCGCAGACTTGGGCGCGCGCCAGAACGCCAGCGGCGAGATGGCCGATTCCGGC ACGCTGCTGCGCGAACGCTATCACCCGATCGTGCTGGCGCTGCGCCAGATGCCCAAGCCCGTGATCAGCGCGGTGAACGG CGTTGCCGCCGGCGCAGGCATGAGCCTCGCGCTGGCTGCCGATGTGGTGCTGGCCGGGAAATCGGCCTCGTTCCTGCAAG CCTTTTCGAAGATCGGCCTCGTGCCGGATGCTGGCAGCACGTACTTCGTGCCGCGCTATGCGGGCGAAATGCGCGCCCGT GCGCTCGCCATCCTGGCCGAGAAGATCGATGCGGAAGAAGCCCAGCGTATCGGCCTGGTGTGGAAGGTCCACGCCGACGA CGCGCTGCAGGCCGAGGCCAGCAAGATGGCGAGCCACCTCGCCAATATGCCGACCTTCGCCTACGGCCTGATCAAGGAAG CGCTCAACGCGAGCTCCGGCAATGATCTCGCGACGCAGCTCGAGCTGGAGGCCTCGCAACAGTCGCGTGCGTGCCGCAGC GAGGACTTCCGCGAAGGCGTGGCCGCCTTCGTCGCCAAGCGCCCGCCGCAGTTCAAGGGCCGCTGA
Upstream 100 bases:
>100_bases GGCACCATCCTGGATTGCGACGGCGGCAGCAAGCTCGGCGATGCGTCGGCCGATGCCCTGAAGACGAAGTGAACCCCGAT TCACGAAGGAAAACACCGCA
Downstream 100 bases:
>100_bases TCGCCCCGTCGCCGTTTGCAGCACCCCCGGGATGGCCGTCCCGGGGCATCACGAGAACAACACAGGGAGACGCATCATGC TGGGCCTCATGCAAGACCGT
Product: enoyl-CoA hydratase / short chain enoyl-CoA hydratase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 261; Mature: 260
Protein sequence:
>261_residues MTSPVLYHASEGVATITLNRPEVLNALNAELLRELRAAVDRAAADESVRAVVLTGAGRGFSSGADLGARQNASGEMADSG TLLRERYHPIVLALRQMPKPVISAVNGVAAGAGMSLALAADVVLAGKSASFLQAFSKIGLVPDAGSTYFVPRYAGEMRAR ALAILAEKIDAEEAQRIGLVWKVHADDALQAEASKMASHLANMPTFAYGLIKEALNASSGNDLATQLELEASQQSRACRS EDFREGVAAFVAKRPPQFKGR
Sequences:
>Translated_261_residues MTSPVLYHASEGVATITLNRPEVLNALNAELLRELRAAVDRAAADESVRAVVLTGAGRGFSSGADLGARQNASGEMADSG TLLRERYHPIVLALRQMPKPVISAVNGVAAGAGMSLALAADVVLAGKSASFLQAFSKIGLVPDAGSTYFVPRYAGEMRAR ALAILAEKIDAEEAQRIGLVWKVHADDALQAEASKMASHLANMPTFAYGLIKEALNASSGNDLATQLELEASQQSRACRS EDFREGVAAFVAKRPPQFKGR >Mature_260_residues TSPVLYHASEGVATITLNRPEVLNALNAELLRELRAAVDRAAADESVRAVVLTGAGRGFSSGADLGARQNASGEMADSGT LLRERYHPIVLALRQMPKPVISAVNGVAAGAGMSLALAADVVLAGKSASFLQAFSKIGLVPDAGSTYFVPRYAGEMRARA LAILAEKIDAEEAQRIGLVWKVHADDALQAEASKMASHLANMPTFAYGLIKEALNASSGNDLATQLELEASQQSRACRSE DFREGVAAFVAKRPPQFKGR
Specific function: Could possibly oxidize fatty acids using specific components [H]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=36.4372469635627, Blast_Score=142, Evalue=4e-34, Organism=Homo sapiens, GI45643119, Length=216, Percent_Identity=32.8703703703704, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI260275230, Length=216, Percent_Identity=32.8703703703704, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI260274832, Length=216, Percent_Identity=32.8703703703704, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI70995211, Length=187, Percent_Identity=33.1550802139037, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=27.4900398406374, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4757968, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI49355787, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4757966, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI51538581, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI25453481, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI51538573, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI221136756, Length=179, Percent_Identity=32.4022346368715, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI221136753, Length=179, Percent_Identity=32.4022346368715, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI221307494, Length=167, Percent_Identity=34.7305389221557, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI68989263, Length=231, Percent_Identity=28.1385281385281, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI37594471, Length=179, Percent_Identity=27.9329608938547, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI37594469, Length=179, Percent_Identity=27.9329608938547, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI116235487, Length=160, Percent_Identity=33.125, Blast_Score=77, Evalue=2e-14, Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=48.8549618320611, Blast_Score=234, Evalue=4e-63, Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=37.1647509578544, Blast_Score=134, Evalue=6e-33, Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=31.3725490196078, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=32.3308270676692, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=26.4822134387352, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1788682, Length=192, Percent_Identity=26.5625, Blast_Score=64, Evalue=9e-12, Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=37.2, Blast_Score=146, Evalue=1e-35, Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=35.4581673306773, Blast_Score=139, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17535521, Length=248, Percent_Identity=29.0322580645161, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17549921, Length=219, Percent_Identity=29.6803652968037, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17540306, Length=265, Percent_Identity=31.6981132075472, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=29.4930875576037, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17540714, Length=230, Percent_Identity=30.8695652173913, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560910, Length=193, Percent_Identity=27.979274611399, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17558304, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI25144157, Length=215, Percent_Identity=26.5116279069767, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25144160, Length=215, Percent_Identity=26.5116279069767, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25141363, Length=169, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17508953, Length=144, Percent_Identity=31.9444444444444, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI25144276, Length=144, Percent_Identity=31.9444444444444, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17508951, Length=144, Percent_Identity=31.9444444444444, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6320241, Length=227, Percent_Identity=26.8722466960352, Blast_Score=88, Evalue=1e-18, Organism=Drosophila melanogaster, GI20129971, Length=252, Percent_Identity=34.1269841269841, Blast_Score=141, Evalue=4e-34, Organism=Drosophila melanogaster, GI24653477, Length=252, Percent_Identity=34.1269841269841, Blast_Score=141, Evalue=4e-34, Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=31.5384615384615, Blast_Score=110, Evalue=8e-25, Organism=Drosophila melanogaster, GI19920382, Length=261, Percent_Identity=29.8850574712644, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24654903, Length=240, Percent_Identity=25.4166666666667, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI19922422, Length=265, Percent_Identity=26.7924528301887, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI28571730, Length=157, Percent_Identity=31.2101910828025, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571729, Length=157, Percent_Identity=31.2101910828025, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357171, Length=202, Percent_Identity=29.7029702970297, Blast_Score=71, Evalue=8e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001753 - InterPro: IPR011968 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.17 [H]
Molecular weight: Translated: 27519; Mature: 27387
Theoretical pI: Translated: 7.67; Mature: 7.67
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSPVLYHASEGVATITLNRPEVLNALNAELLRELRAAVDRAAADESVRAVVLTGAGRGF CCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC SSGADLGARQNASGEMADSGTLLRERYHPIVLALRQMPKPVISAVNGVAAGAGMSLALAA CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH DVVLAGKSASFLQAFSKIGLVPDAGSTYFVPRYAGEMRARALAILAEKIDAEEAQRIGLV HHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCHHHHHHCCEE WKVHADDALQAEASKMASHLANMPTFAYGLIKEALNASSGNDLATQLELEASQQSRACRS EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHHHHHHH EDFREGVAAFVAKRPPQFKGR HHHHHHHHHHHHCCCCCCCCC >Mature Secondary Structure TSPVLYHASEGVATITLNRPEVLNALNAELLRELRAAVDRAAADESVRAVVLTGAGRGF CCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC SSGADLGARQNASGEMADSGTLLRERYHPIVLALRQMPKPVISAVNGVAAGAGMSLALAA CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH DVVLAGKSASFLQAFSKIGLVPDAGSTYFVPRYAGEMRARALAILAEKIDAEEAQRIGLV HHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCHHHHHHCCEE WKVHADDALQAEASKMASHLANMPTFAYGLIKEALNASSGNDLATQLELEASQQSRACRS EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHHHHHHH EDFREGVAAFVAKRPPQFKGR HHHHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9748275; 9097039; 9278503; 10766858 [H]