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The map label for this gene is ygfU [H]

Identifier: 73542764

GI number: 73542764

Start: 3390992

End: 3392341

Strand: Direct

Name: ygfU [H]

Synonym: Reut_A3080

Alternate gene names: 73542764

Gene position: 3390992-3392341 (Clockwise)

Preceding gene: 73542762

Following gene: 73542765

Centisome position: 89.08

GC content: 64.0

Gene sequence:

>1350_bases
ATGACAACTGCCGTGCACCCCGTCGATCAGATATTGCCCGCGCGCGCCATGGCGTCGCTGGGCTTCCAGCACATGCTGGT
GAGCTACCTCGGAGCAATCGCCGTACCGATGATTGTAGCGAGCGCGCTGAAGATGACCCCTGCGCAGACGACCATGCTGA
TCAGCACGGCGCTGTTCACATCCGGCATCGCCACATTGCTCCAGACCGTGGGCTTCTGGAAATTCGGAGTACGGCTGCCG
CTGATGCAAGGCGTGGCATTCAGCTCAGTCGCGCCGGTGATCGCGATCGGCAGCGACCCGTCGCTGGGCTTCAATGGCGT
GTGCGGCGCCATCATCGGCGCAGGCGTGATCACGATGCTGCTCGCGCCCGTGATCGGGCGGCTCAAGCGCTTTTTTCCGC
CGGTGGTCAGCGGCTGCACCATCACCGCGGTGGGGCTGTCGCTGTTCCCTGTGTCGTTTCACTGGTTTGGCGGTGGGAGG
GGTGCGCCGGATTTTGGCAGCCCCGTCTTTTTCGCGGTCGGCTTCGGTGTGGTGGCGCTGATCCTGCTCATCAACCGCCA
CCGCAGCGAACTGGTGCGCAACCTGGCGGTGATGATCGGCCTGCTTGTCGGCGGCGCCGTGGCGTGGATGCTCGGCATGG
GCAACTTCGATGAAGTGTCGCGCGCGCCGTGGTTCACGATGGTCACGCCATTTGCATTCGGCATGCCCGTTTTCGATATT
GGCGCCATCACGACGATGGTGATCGTGATGGTTGTGCAGATGGTGGAATCGATGGGCCTGTTCGTGGCTGTCAGCGAGAT
CGTCAAGCGCCCTATCACCGAACAGGACGCCACGCGCGGACTACGCGCCAACGGGCTTGCCAGTGCCATCGGCGGCATGT
TCGCGGCGTTTCCGTATATCGCCTTCATGGAGAACGTGGGGCTCGTGATCGTCACCGGCGTGCGCAGCCGCTGGGTGGTT
GCGACCTGCGGCGTGATGCTGTGCGCGGTGGCGCTGGTGCCGAAGATTGGCGCGCTGTTCGCGTCGATCCCGCCTGCGGC
ACTCGGCGGCGCGGCGATGGTGATGTTCGGCGTGGTTGTAGCGGCCGGCATCAAGACGCTGGGCCGAGTCGAATACGACC
GCAATCCGGCCAACCTGTCGGTAGTTGCCATCACGCTCGCCTGCGCCATGATGCCCGTGATGCTGCCGTCGATGCTCGAT
AAGCTGCCCGGCTTCCTGCAGCCGTTCGTGCACAGCAGCGTGATCATCGCGTGCGTGGTCTCCGTACTGCTGAACCTGCT
GCTCAATGGCGTGCCCGCGCGTGACGAGAGCGAGCACCCGATCCATACCGACAACATCCAGGAGGTCTGA

Upstream 100 bases:

>100_bases
AAGCGCGCGGCGCACGCCGCTATCTTCCATGCATGCACCGGCGGCCAGCCGCAGCCGGCACGGTGCGCGTCCCCCAACGA
CAGCGGCAGGAGACACCACC

Downstream 100 bases:

>100_bases
ACATGGTGTCCACCGCTGCCGCCCCGACGGGCAATCTGCTGATCCGCAACGCCGCCGCCGTGATGACAGGGCGCGCCGGC
GACCCCGCGCGCGCGGGGGC

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTTAVHPVDQILPARAMASLGFQHMLVSYLGAIAVPMIVASALKMTPAQTTMLISTALFTSGIATLLQTVGFWKFGVRLP
LMQGVAFSSVAPVIAIGSDPSLGFNGVCGAIIGAGVITMLLAPVIGRLKRFFPPVVSGCTITAVGLSLFPVSFHWFGGGR
GAPDFGSPVFFAVGFGVVALILLINRHRSELVRNLAVMIGLLVGGAVAWMLGMGNFDEVSRAPWFTMVTPFAFGMPVFDI
GAITTMVIVMVVQMVESMGLFVAVSEIVKRPITEQDATRGLRANGLASAIGGMFAAFPYIAFMENVGLVIVTGVRSRWVV
ATCGVMLCAVALVPKIGALFASIPPAALGGAAMVMFGVVVAAGIKTLGRVEYDRNPANLSVVAITLACAMMPVMLPSMLD
KLPGFLQPFVHSSVIIACVVSVLLNLLLNGVPARDESEHPIHTDNIQEV

Sequences:

>Translated_449_residues
MTTAVHPVDQILPARAMASLGFQHMLVSYLGAIAVPMIVASALKMTPAQTTMLISTALFTSGIATLLQTVGFWKFGVRLP
LMQGVAFSSVAPVIAIGSDPSLGFNGVCGAIIGAGVITMLLAPVIGRLKRFFPPVVSGCTITAVGLSLFPVSFHWFGGGR
GAPDFGSPVFFAVGFGVVALILLINRHRSELVRNLAVMIGLLVGGAVAWMLGMGNFDEVSRAPWFTMVTPFAFGMPVFDI
GAITTMVIVMVVQMVESMGLFVAVSEIVKRPITEQDATRGLRANGLASAIGGMFAAFPYIAFMENVGLVIVTGVRSRWVV
ATCGVMLCAVALVPKIGALFASIPPAALGGAAMVMFGVVVAAGIKTLGRVEYDRNPANLSVVAITLACAMMPVMLPSMLD
KLPGFLQPFVHSSVIIACVVSVLLNLLLNGVPARDESEHPIHTDNIQEV
>Mature_448_residues
TTAVHPVDQILPARAMASLGFQHMLVSYLGAIAVPMIVASALKMTPAQTTMLISTALFTSGIATLLQTVGFWKFGVRLPL
MQGVAFSSVAPVIAIGSDPSLGFNGVCGAIIGAGVITMLLAPVIGRLKRFFPPVVSGCTITAVGLSLFPVSFHWFGGGRG
APDFGSPVFFAVGFGVVALILLINRHRSELVRNLAVMIGLLVGGAVAWMLGMGNFDEVSRAPWFTMVTPFAFGMPVFDIG
AITTMVIVMVVQMVESMGLFVAVSEIVKRPITEQDATRGLRANGLASAIGGMFAAFPYIAFMENVGLVIVTGVRSRWVVA
TCGVMLCAVALVPKIGALFASIPPAALGGAAMVMFGVVVAAGIKTLGRVEYDRNPANLSVVAITLACAMMPVMLPSMLDK
LPGFLQPFVHSSVIIACVVSVLLNLLLNGVPARDESEHPIHTDNIQEV

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=460, Percent_Identity=24.3478260869565, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI44680143, Length=464, Percent_Identity=24.1379310344828, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI44680148, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40316845, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082181, Length=442, Percent_Identity=44.7963800904977, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1790087, Length=420, Percent_Identity=28.8095238095238, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87082178, Length=433, Percent_Identity=31.6397228637413, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87081818, Length=401, Percent_Identity=28.927680798005, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788843, Length=390, Percent_Identity=27.1794871794872, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17558856, Length=402, Percent_Identity=25.1243781094527, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17541904, Length=428, Percent_Identity=24.2990654205607, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=446, Percent_Identity=21.9730941704036, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356175, Length=498, Percent_Identity=24.0963855421687, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47073; Mature: 46942

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTAVHPVDQILPARAMASLGFQHMLVSYLGAIAVPMIVASALKMTPAQTTMLISTALFT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH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HHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]