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The map label for this gene is yjiA [H]

Identifier: 73542762

GI number: 73542762

Start: 3388597

End: 3389679

Strand: Direct

Name: yjiA [H]

Synonym: Reut_A3078

Alternate gene names: 73542762

Gene position: 3388597-3389679 (Clockwise)

Preceding gene: 73542761

Following gene: 73542764

Centisome position: 89.02

GC content: 61.96

Gene sequence:

>1083_bases
ATGACGCACCACGCCACGCAGTTGCCGCCCGTACCGGTCACCATCCTCACCGGCTTCCTTGGCTCCGGCAAGACCACGCT
GCTGAACCACATCCTGACGCAGAAGCACGGGCACCGCATCGCGGTGATCGAGAACGAGTTCGGCGAGGTCGATGTCGACT
CCGATCTCGTGATGACTTCCGACGAAGAGATCTACCAGATGACCAACGGCTGCATCTGCTGCGTTGTGGACGTGCGCACG
GACCTCGTGCGCATCCTGCAGAAGCTGCTCGAGCGGCCCGAGCGATTCGACCACATCCTCGTGGAGACCAGCGGCCTGGC
CGACCCGACGCCAGTGGCCGCGACCTTCTTCATGGACCATGAAGTTGCGCAGCAGGTAAGACTCGATGGCATTCTGACGC
TCGTGGATGCGGTGCACATCGAAGATCACCTCGATGATCCGCAACTGACAGGGTTCGACAACCAGGCCGTGGACCAGATT
GTCGCGGCGGACCGCGTCATCCTGAACAAGACCGATCTCGTCAGTGCCGCGCGGCTCGACGCACTCGAAGCGCGCATCCA
CAAGCTCAATGAAGGCGCGCAGATCCTGCGCTCCAACTATGCGCAGGTCGATCTAGGCAAGATCCTCGGCATCGGCGGGT
TCACGCCGGGCATAGTGCAGATGGAGGATCACGGACATGCGCATCACGAGCACGATCATGCTGGCCACGTCTGCGACGAG
CATTGCGACCATGCGCATGATGAGGCCGAGCATGGTCATCGTCATGATCCATCGGTGACATCGGTCTCGCTGGTGTTCGA
CCAGCCATTCGATCGCCAGCGGCTTGAATACGGCTTGCGGGCATTGCTCGCCGCACAGGGCGACGATGTATTCCGCATGA
AAGGCATCGTCGCCGTGGCCGGCGATACGCAGCGCTACGTGTTGCAGGCCGTGCACCGGCTCATGGATTTCCGTGCGGAC
GCGCCATGGGGCACGGAAGCGCCGCAGAGCAAGTTCGTGTTCATCGGCCGCAACCTGGACAAGCAGCGGCTGCAGACACT
GCTGAACGTTTGCATGCCGGTGCGCGTAGCAGAAGCGGCGTAA

Upstream 100 bases:

>100_bases
GCAGCGCTGGGAAGGCCTGCGCCCTGCCATCGGCGCCGCATAGCCCACGTTTCGCTTATCGCCCCGCCAACGGGGAACGC
AGTTTGAATCAGGAGACAAC

Downstream 100 bases:

>100_bases
TGTCCCTGGCGGGTTAACCGGCTGAAGCGCGTCTCTGTCGTGGAGACCGCTTCAGCCCCGCGGCGCCTGCAAGGTATCCG
ACGGCAGTTCGCCGAACGCC

Product: cobalamin synthesis protein/P47K:cobalamin synthesis CobW, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTHHATQLPPVPVTILTGFLGSGKTTLLNHILTQKHGHRIAVIENEFGEVDVDSDLVMTSDEEIYQMTNGCICCVVDVRT
DLVRILQKLLERPERFDHILVETSGLADPTPVAATFFMDHEVAQQVRLDGILTLVDAVHIEDHLDDPQLTGFDNQAVDQI
VAADRVILNKTDLVSAARLDALEARIHKLNEGAQILRSNYAQVDLGKILGIGGFTPGIVQMEDHGHAHHEHDHAGHVCDE
HCDHAHDEAEHGHRHDPSVTSVSLVFDQPFDRQRLEYGLRALLAAQGDDVFRMKGIVAVAGDTQRYVLQAVHRLMDFRAD
APWGTEAPQSKFVFIGRNLDKQRLQTLLNVCMPVRVAEAA

Sequences:

>Translated_360_residues
MTHHATQLPPVPVTILTGFLGSGKTTLLNHILTQKHGHRIAVIENEFGEVDVDSDLVMTSDEEIYQMTNGCICCVVDVRT
DLVRILQKLLERPERFDHILVETSGLADPTPVAATFFMDHEVAQQVRLDGILTLVDAVHIEDHLDDPQLTGFDNQAVDQI
VAADRVILNKTDLVSAARLDALEARIHKLNEGAQILRSNYAQVDLGKILGIGGFTPGIVQMEDHGHAHHEHDHAGHVCDE
HCDHAHDEAEHGHRHDPSVTSVSLVFDQPFDRQRLEYGLRALLAAQGDDVFRMKGIVAVAGDTQRYVLQAVHRLMDFRAD
APWGTEAPQSKFVFIGRNLDKQRLQTLLNVCMPVRVAEAA
>Mature_359_residues
THHATQLPPVPVTILTGFLGSGKTTLLNHILTQKHGHRIAVIENEFGEVDVDSDLVMTSDEEIYQMTNGCICCVVDVRTD
LVRILQKLLERPERFDHILVETSGLADPTPVAATFFMDHEVAQQVRLDGILTLVDAVHIEDHLDDPQLTGFDNQAVDQIV
AADRVILNKTDLVSAARLDALEARIHKLNEGAQILRSNYAQVDLGKILGIGGFTPGIVQMEDHGHAHHEHDHAGHVCDEH
CDHAHDEAEHGHRHDPSVTSVSLVFDQPFDRQRLEYGLRALLAAQGDDVFRMKGIVAVAGDTQRYVLQAVHRLMDFRADA
PWGTEAPQSKFVFIGRNLDKQRLQTLLNVCMPVRVAEAA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=355, Percent_Identity=33.2394366197183, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI126722884, Length=355, Percent_Identity=32.9577464788732, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI148727351, Length=355, Percent_Identity=32.9577464788732, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI146231952, Length=357, Percent_Identity=33.6134453781513, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI223941779, Length=345, Percent_Identity=32.463768115942, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI223941776, Length=345, Percent_Identity=31.8840579710145, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI119120938, Length=162, Percent_Identity=40.7407407407407, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI87082430, Length=340, Percent_Identity=34.4117647058824, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788499, Length=222, Percent_Identity=28.3783783783784, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324356, Length=380, Percent_Identity=28.4210526315789, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 39956; Mature: 39825

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHHATQLPPVPVTILTGFLGSGKTTLLNHILTQKHGHRIAVIENEFGEVDVDSDLVMTS
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEC
DEEIYQMTNGCICCVVDVRTDLVRILQKLLERPERFDHILVETSGLADPTPVAATFFMDH
CHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCHHHHCEEEEEECCCCCCCCHHHHHHHHH
EVAQQVRLDGILTLVDAVHIEDHLDDPQLTGFDNQAVDQIVAADRVILNKTDLVSAARLD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCHHHHHHHHHH
ALEARIHKLNEGAQILRSNYAQVDLGKILGIGGFTPGIVQMEDHGHAHHEHDHAGHVCDE
HHHHHHHHHHHHHHHHHCCCCCEEHHHHEECCCCCCCEEEECCCCCCCCCCCCCCCHHHH
HCDHAHDEAEHGHRHDPSVTSVSLVFDQPFDRQRLEYGLRALLAAQGDDVFRMKGIVAVA
HHCCCCHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEEE
GDTQRYVLQAVHRLMDFRADAPWGTEAPQSKFVFIGRNLDKQRLQTLLNVCMPVRVAEAA
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
THHATQLPPVPVTILTGFLGSGKTTLLNHILTQKHGHRIAVIENEFGEVDVDSDLVMTS
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEC
DEEIYQMTNGCICCVVDVRTDLVRILQKLLERPERFDHILVETSGLADPTPVAATFFMDH
CHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCHHHHCEEEEEECCCCCCCCHHHHHHHHH
EVAQQVRLDGILTLVDAVHIEDHLDDPQLTGFDNQAVDQIVAADRVILNKTDLVSAARLD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCHHHHHHHHHH
ALEARIHKLNEGAQILRSNYAQVDLGKILGIGGFTPGIVQMEDHGHAHHEHDHAGHVCDE
HHHHHHHHHHHHHHHHHCCCCCEEHHHHEECCCCCCCEEEECCCCCCCCCCCCCCCHHHH
HCDHAHDEAEHGHRHDPSVTSVSLVFDQPFDRQRLEYGLRALLAAQGDDVFRMKGIVAVA
HHCCCCHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCEEEEE
GDTQRYVLQAVHRLMDFRADAPWGTEAPQSKFVFIGRNLDKQRLQTLLNVCMPVRVAEAA
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]