Click here to switch to the map view.

The map label for this gene is lrp [C]

Identifier: 73542736

GI number: 73542736

Start: 3355273

End: 3355731

Strand: Direct

Name: lrp [C]

Synonym: Reut_A3052

Alternate gene names: 73542736

Gene position: 3355273-3355731 (Clockwise)

Preceding gene: 73542732

Following gene: 73542737

Centisome position: 88.15

GC content: 67.97

Gene sequence:

>459_bases
ATGGCTGACACCGACAAGCTTGACCAGACCGACCGGCACCTGCTGTCGCTGTTGCAGGCCAACGCGCGCGAAAGCGCGGC
CAACCTCGCACGCCATCTCGATATCGCGCGGACTACGGTGGTGGCGCGCATCGCGCGGCTGGAGCGGCTCGGCGTGATTG
CCGGCTATGGCGTGCGGCTCGGCCGCGAGATGGGCGACAACGCGATCCAGGCGTTCTGCGGGCTGTCGGTCCAGCCCAAG
GCCGGCCCGGCCATCGTGCGCGCGCTGCAGCGGCTGCCGGAGATCGAGGAGTTGAGTTCTGTCAGCGGGCCGGTGGACTA
CATGGCGGTGATCCGCTGCGTCACGCACGCGCGCCTCGACCAGTTGCTCGACGAGATCGGCATGCTCGACGGCGTGAACC
ACACCACCACGTCGATCGTGCTCGCGCGAAAAATCGACCGCCGGCGAGCAACGGAATAG

Upstream 100 bases:

>100_bases
GTGCCTGATTGGAGTATGGGCAGCGCGCGCAACAGAAAGAAGGGTCGAGTTCGACGAATACCGTCCATAATCGAACGAAA
CGACGACGGATTTCGACGAA

Downstream 100 bases:

>100_bases
CGCGGTATCCTCCACCGACCGCAATCCACCCAACGGAGCAAAAACAATGAGCAATCCGATCCGTGTCGCCGTAGGCGGCG
TAACCGGCTGGGCCGGCGGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MADTDKLDQTDRHLLSLLQANARESAANLARHLDIARTTVVARIARLERLGVIAGYGVRLGREMGDNAIQAFCGLSVQPK
AGPAIVRALQRLPEIEELSSVSGPVDYMAVIRCVTHARLDQLLDEIGMLDGVNHTTTSIVLARKIDRRRATE

Sequences:

>Translated_152_residues
MADTDKLDQTDRHLLSLLQANARESAANLARHLDIARTTVVARIARLERLGVIAGYGVRLGREMGDNAIQAFCGLSVQPK
AGPAIVRALQRLPEIEELSSVSGPVDYMAVIRCVTHARLDQLLDEIGMLDGVNHTTTSIVLARKIDRRRATE
>Mature_151_residues
ADTDKLDQTDRHLLSLLQANARESAANLARHLDIARTTVVARIARLERLGVIAGYGVRLGREMGDNAIQAFCGLSVQPKA
GPAIVRALQRLPEIEELSSVSGPVDYMAVIRCVTHARLDQLLDEIGMLDGVNHTTTSIVLARKIDRRRATE

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=150, Percent_Identity=32.6666666666667, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013249
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 16635; Mature: 16504

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTDKLDQTDRHLLSLLQANARESAANLARHLDIARTTVVARIARLERLGVIAGYGVRL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GREMGDNAIQAFCGLSVQPKAGPAIVRALQRLPEIEELSSVSGPVDYMAVIRCVTHARLD
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
QLLDEIGMLDGVNHTTTSIVLARKIDRRRATE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADTDKLDQTDRHLLSLLQANARESAANLARHLDIARTTVVARIARLERLGVIAGYGVRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GREMGDNAIQAFCGLSVQPKAGPAIVRALQRLPEIEELSSVSGPVDYMAVIRCVTHARLD
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
QLLDEIGMLDGVNHTTTSIVLARKIDRRRATE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]