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The map label for this gene is paaK [H]

Identifier: 73542701

GI number: 73542701

Start: 3319895

End: 3321199

Strand: Direct

Name: paaK [H]

Synonym: Reut_A3017

Alternate gene names: 73542701

Gene position: 3319895-3321199 (Clockwise)

Preceding gene: 73542700

Following gene: 73542703

Centisome position: 87.22

GC content: 66.74

Gene sequence:

>1305_bases
ATGAGCACGCGCCTGACCGATCTGCCGCTCGAGCCTATCGAGACCGCCAGCCGCGACGAATTGCGGGCACTCCAGCTCGA
GCGCCTGAAATGGTCGCTGCGGCATGCCTACGATAACTCGCCGGTCTACCGCCGCAAATTCGACGAGGCCGGCGTGCATC
CCGATCAGGTCCAGACGCTCGCAGACCTCGCGCGCTTCCCGTTCACCACCAAACAGGACCTGCGCGACAACTATCCGTTC
GGCATGTTCGCGGTGCCGCAGGACCGCGTGGCGCGCGTGCATGCATCGTCGGGCACTACGGGCAAGCCGACCGTGGTCGG
TTACACGCTCAAGGACATCGACACGTGGGCCACGGTGATGGCGCGCTCGATCCGGGCTGCCGGAGCGAGGCGTTGCGACA
AGGTGCACGTCAGCTATGGCTATGGCCTGTTCACGGGCGGCCTCGGCGCGCACTACGGCGTGGAAAAGGCCGGCCTGACG
GCGATCCCGTTCGGCGGCGGGCAGACCGAACGCCAGGTGCAGCTGATCATGGATTTCAAGCCCGAGATCATCATGGTCAC
GCCGAGCTATATGCTCGCCATCGCCGACGAATTCGAGCGCCAGGGCATCGATCCCGCCACGACGTCGCTGCGCGTCGGCA
TCTTCGGGGCCGAGCCGTGGACGCCGGAAATGCGCCTCGCGATCGAGAAGCGCATGAATATCTCGGCCGTCGACATCTAT
GGCCTGTCCGAAGTGATGGGCCCGGGCGTGGCCAATGAATGCGCCGAGACCAAGGACGGCCCGACCATCTGGGAAGATCA
CTTCTACCCCGAGATCATCGACCCGGATACCGGTGAGGTACTTCCCGACGGCGAGTTCGGCGAACTCGTGTTCACGTCAC
TGACCAAGGAAGCGATGCCGGTGGTCCGCTACCGCACGCGCGACCTGACGCGCCTGCTGCCGGGCACCGCGCGCGCGGCG
TTCCGGCGCATGGAGAAGGTCACCGGCCGGACCGACGACATGATGATCGTGCGCGGCGTGAACGTGTTCCCGTCGCAGAT
CGAGGAGCTGATCCTGAAGCGCCCGGAACTGGCGCCGCACTACCAGTGCGTGCTGACGCGCGAAGGGCCGATGGACCTGC
TGACAGTGCGCGTGGAATGCGCCCACGGCGGCGAACCGGCGACGGCGCAAGCCGCTCGCGAGGCACTGGCCCACGACATC
AAGGCCTATATCGGCGTGAGCGCCGGCATCGAGGTGCTGCCGACCGGCGGCATCGAGCGCTCGGTCGGCAAGGCGCGGCG
CATCGTCGACCAGCGCCCACGCTGA

Upstream 100 bases:

>100_bases
GACAGCAGCAGCACCTGAAGTTCGCCAGGCCCGTGGCCTGACCCCGCACAAGACGATTTCACGATTCCATCGACAAGAAC
GCCCACGTGCAGGAGACGAT

Downstream 100 bases:

>100_bases
TAGTTACCGCGCGGCGCGTCAGCTGCGCGGCATCAGCACCCACATCCGGCCGCCCTGCTTCATGCGGCCGGCCGTCTCGC
CCGCGGCATCGCCCGCGCCC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSTRLTDLPLEPIETASRDELRALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDQVQTLADLARFPFTTKQDLRDNYPF
GMFAVPQDRVARVHASSGTTGKPTVVGYTLKDIDTWATVMARSIRAAGARRCDKVHVSYGYGLFTGGLGAHYGVEKAGLT
AIPFGGGQTERQVQLIMDFKPEIIMVTPSYMLAIADEFERQGIDPATTSLRVGIFGAEPWTPEMRLAIEKRMNISAVDIY
GLSEVMGPGVANECAETKDGPTIWEDHFYPEIIDPDTGEVLPDGEFGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARAA
FRRMEKVTGRTDDMMIVRGVNVFPSQIEELILKRPELAPHYQCVLTREGPMDLLTVRVECAHGGEPATAQAAREALAHDI
KAYIGVSAGIEVLPTGGIERSVGKARRIVDQRPR

Sequences:

>Translated_434_residues
MSTRLTDLPLEPIETASRDELRALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDQVQTLADLARFPFTTKQDLRDNYPF
GMFAVPQDRVARVHASSGTTGKPTVVGYTLKDIDTWATVMARSIRAAGARRCDKVHVSYGYGLFTGGLGAHYGVEKAGLT
AIPFGGGQTERQVQLIMDFKPEIIMVTPSYMLAIADEFERQGIDPATTSLRVGIFGAEPWTPEMRLAIEKRMNISAVDIY
GLSEVMGPGVANECAETKDGPTIWEDHFYPEIIDPDTGEVLPDGEFGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARAA
FRRMEKVTGRTDDMMIVRGVNVFPSQIEELILKRPELAPHYQCVLTREGPMDLLTVRVECAHGGEPATAQAAREALAHDI
KAYIGVSAGIEVLPTGGIERSVGKARRIVDQRPR
>Mature_433_residues
STRLTDLPLEPIETASRDELRALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDQVQTLADLARFPFTTKQDLRDNYPFG
MFAVPQDRVARVHASSGTTGKPTVVGYTLKDIDTWATVMARSIRAAGARRCDKVHVSYGYGLFTGGLGAHYGVEKAGLTA
IPFGGGQTERQVQLIMDFKPEIIMVTPSYMLAIADEFERQGIDPATTSLRVGIFGAEPWTPEMRLAIEKRMNISAVDIYG
LSEVMGPGVANECAETKDGPTIWEDHFYPEIIDPDTGEVLPDGEFGELVFTSLTKEAMPVVRYRTRDLTRLLPGTARAAF
RRMEKVTGRTDDMMIVRGVNVFPSQIEELILKRPELAPHYQCVLTREGPMDLLTVRVECAHGGEPATAQAAREALAHDIK
AYIGVSAGIEVLPTGGIERSVGKARRIVDQRPR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=432, Percent_Identity=63.1944444444444, Blast_Score=567, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48147; Mature: 48015

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRLTDLPLEPIETASRDELRALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDQVQTL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHH
ADLARFPFTTKQDLRDNYPFGMFAVPQDRVARVHASSGTTGKPTVVGYTLKDIDTWATVM
HHHHHCCCCCHHHHHCCCCCCEEECCHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHH
ARSIRAAGARRCDKVHVSYGYGLFTGGLGAHYGVEKAGLTAIPFGGGQTERQVQLIMDFK
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECC
PEIIMVTPSYMLAIADEFERQGIDPATTSLRVGIFGAEPWTPEMRLAIEKRMNISAVDIY
CCEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEC
GLSEVMGPGVANECAETKDGPTIWEDHFYPEIIDPDTGEVLPDGEFGELVFTSLTKEAMP
CHHHHHCCCCHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VVRYRTRDLTRLLPGTARAAFRRMEKVTGRTDDMMIVRGVNVFPSQIEELILKRPELAPH
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCC
YQCVLTREGPMDLLTVRVECAHGGEPATAQAAREALAHDIKAYIGVSAGIEVLPTGGIER
EEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
SVGKARRIVDQRPR
HHHHHHHHHHCCCC
>Mature Secondary Structure 
STRLTDLPLEPIETASRDELRALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDQVQTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHH
ADLARFPFTTKQDLRDNYPFGMFAVPQDRVARVHASSGTTGKPTVVGYTLKDIDTWATVM
HHHHHCCCCCHHHHHCCCCCCEEECCHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHH
ARSIRAAGARRCDKVHVSYGYGLFTGGLGAHYGVEKAGLTAIPFGGGQTERQVQLIMDFK
HHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECC
PEIIMVTPSYMLAIADEFERQGIDPATTSLRVGIFGAEPWTPEMRLAIEKRMNISAVDIY
CCEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEC
GLSEVMGPGVANECAETKDGPTIWEDHFYPEIIDPDTGEVLPDGEFGELVFTSLTKEAMP
CHHHHHCCCCHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VVRYRTRDLTRLLPGTARAAFRRMEKVTGRTDDMMIVRGVNVFPSQIEELILKRPELAPH
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCC
YQCVLTREGPMDLLTVRVECAHGGEPATAQAAREALAHDIKAYIGVSAGIEVLPTGGIER
EEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
SVGKARRIVDQRPR
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]