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The map label for this gene is lrhA [H]

Identifier: 73542564

GI number: 73542564

Start: 3155093

End: 3155971

Strand: Reverse

Name: lrhA [H]

Synonym: Reut_A2879

Alternate gene names: 73542564

Gene position: 3155971-3155093 (Counterclockwise)

Preceding gene: 73542570

Following gene: 73542563

Centisome position: 82.91

GC content: 68.94

Gene sequence:

>879_bases
ATGCGCGGATTCGATACGGACCACTTGCGCACCTTCGTCACAGTGGCCGACAGCGGCAGCCTGTCCGCGGCGGCGCCCCG
GCTGTTTCTGTCGCAGTCCTCGGTCAGCGAGCAATTGCGCAAGCTCGAGGAGCGCGCCGGCGTGCCGCTGCTCACACGCG
GCCGCAAAGGCGCGGTGCCGACGCCTGCCGGGACGCGCCTGCTGGAACATGCGCGGCGCATCCTGGCGCTCAGCGACATG
GCGCTGCAGGAACTGCGCGGCCGCGTGCTGGAAGGGGAGTTGCGGCTCGCGGTGACCGACTATTTCCGGCCTGCGGAGAT
CGCCGGCATGCTGCGCCGCCTGCGCGAACGCCATCCGCTGCTGCGCCTGCACGTCACGGTGATGAAAAGCGCCGTGATCG
ACGCGAGCGCTGACATGGACGCATTCGATATCGGACTGAGCATGCGTATCGTCGGCACGCGCGGCCAGGCGGCAGCGCGA
CGCGGGACCCTGCTGCGTCGCGAGTCGCTGTCATGGGTGACGGCGCAGGGCGAGGCGGGCACCTTGCCGGAGACGCTGCC
GCTGGTGTTGCTGCCTGACTCGTGCTCGCTGCACCAGTTTGTCGTGAAGCTGCTGGTGCGCAAGCGCAGGGCGTTCGAGA
TCGCGCACTCGGCCTCGGGCGTGGCGGGGCTTCATCTCGCTCTGGCTGCAGGGCTGGGCCTCTCGTGCCTGAATGCGTCG
GCGATCGGCCCGGGCGTGGCGCCTCTCGATGCCGCCAGCCAGCGCAGGCGTGGCCTGCCGGCCTTGCCGGAAGCGGAGTT
CTTCCTGTTACCAGCCAAGCGCGGTGAACCGGATTTCATCGCCGCAGCGCGCGATGCGTTGGCAGAACAATTTGGATGA

Upstream 100 bases:

>100_bases
GGTGATGTCATGGTAGGTGGCGGTGTAATATCGGAAAAGCAGGAAGTTCCGATATGAACCATCGGTTTATCCGAATCATC
GAAATCAACGGGGGATCGCC

Downstream 100 bases:

>100_bases
CAAGCTCCGAGCCAGGCTCTGATTGTGATGTAGAGAGCGCCTTACCAGGAATACCAAAGAGGACATTTATCCCCATATTT
GACGCCTCCGCTCCTTGTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MRGFDTDHLRTFVTVADSGSLSAAAPRLFLSQSSVSEQLRKLEERAGVPLLTRGRKGAVPTPAGTRLLEHARRILALSDM
ALQELRGRVLEGELRLAVTDYFRPAEIAGMLRRLRERHPLLRLHVTVMKSAVIDASADMDAFDIGLSMRIVGTRGQAAAR
RGTLLRRESLSWVTAQGEAGTLPETLPLVLLPDSCSLHQFVVKLLVRKRRAFEIAHSASGVAGLHLALAAGLGLSCLNAS
AIGPGVAPLDAASQRRRGLPALPEAEFFLLPAKRGEPDFIAAARDALAEQFG

Sequences:

>Translated_292_residues
MRGFDTDHLRTFVTVADSGSLSAAAPRLFLSQSSVSEQLRKLEERAGVPLLTRGRKGAVPTPAGTRLLEHARRILALSDM
ALQELRGRVLEGELRLAVTDYFRPAEIAGMLRRLRERHPLLRLHVTVMKSAVIDASADMDAFDIGLSMRIVGTRGQAAAR
RGTLLRRESLSWVTAQGEAGTLPETLPLVLLPDSCSLHQFVVKLLVRKRRAFEIAHSASGVAGLHLALAAGLGLSCLNAS
AIGPGVAPLDAASQRRRGLPALPEAEFFLLPAKRGEPDFIAAARDALAEQFG
>Mature_292_residues
MRGFDTDHLRTFVTVADSGSLSAAAPRLFLSQSSVSEQLRKLEERAGVPLLTRGRKGAVPTPAGTRLLEHARRILALSDM
ALQELRGRVLEGELRLAVTDYFRPAEIAGMLRRLRERHPLLRLHVTVMKSAVIDASADMDAFDIGLSMRIVGTRGQAAAR
RGTLLRRESLSWVTAQGEAGTLPETLPLVLLPDSCSLHQFVVKLLVRKRRAFEIAHSASGVAGLHLALAAGLGLSCLNAS
AIGPGVAPLDAASQRRRGLPALPEAEFFLLPAKRGEPDFIAAARDALAEQFG

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=276, Percent_Identity=29.3478260869565, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786713, Length=126, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=195, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789204, Length=264, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31456; Mature: 31456

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFDTDHLRTFVTVADSGSLSAAAPRLFLSQSSVSEQLRKLEERAGVPLLTRGRKGAVP
CCCCCCHHHEEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
TPAGTRLLEHARRILALSDMALQELRGRVLEGELRLAVTDYFRPAEIAGMLRRLRERHPL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCCE
LRLHVTVMKSAVIDASADMDAFDIGLSMRIVGTRGQAAARRGTLLRRESLSWVTAQGEAG
EEHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCC
TLPETLPLVLLPDSCSLHQFVVKLLVRKRRAFEIAHSASGVAGLHLALAAGLGLSCLNAS
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCC
AIGPGVAPLDAASQRRRGLPALPEAEFFLLPAKRGEPDFIAAARDALAEQFG
CCCCCCCCCCHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGFDTDHLRTFVTVADSGSLSAAAPRLFLSQSSVSEQLRKLEERAGVPLLTRGRKGAVP
CCCCCCHHHEEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
TPAGTRLLEHARRILALSDMALQELRGRVLEGELRLAVTDYFRPAEIAGMLRRLRERHPL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCCE
LRLHVTVMKSAVIDASADMDAFDIGLSMRIVGTRGQAAARRGTLLRRESLSWVTAQGEAG
EEHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCC
TLPETLPLVLLPDSCSLHQFVVKLLVRKRRAFEIAHSASGVAGLHLALAAGLGLSCLNAS
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCC
AIGPGVAPLDAASQRRRGLPALPEAEFFLLPAKRGEPDFIAAARDALAEQFG
CCCCCCCCCCHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]