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The map label for this gene is recG [H]

Identifier: 73542491

GI number: 73542491

Start: 3074869

End: 3077055

Strand: Reverse

Name: recG [H]

Synonym: Reut_A2806

Alternate gene names: 73542491

Gene position: 3077055-3074869 (Counterclockwise)

Preceding gene: 73542497

Following gene: 73542490

Centisome position: 80.84

GC content: 68.54

Gene sequence:

>2187_bases
ATGCCCGGAACCGCCACCGAACCCACCGAGGACAAAGCCGAAGCCCCCGACTCAGCGCCGTCCGCGAAGGCCAAGGCAGC
GGGCAAGGCTGGGAGCAAGGCGACGGGCAAGGACAGCAAGCCATCGTCCGCCGTCGCGCGGCTCGCCAAGATGGGGCTGC
GGCGCAGCGTCGACCTCGTGCTGCATCTGCCGATGCGCTACGAGGACGAAACCACGCTGATGCCGATCGCTGAAGCCATC
CGCCGCTCCGGGCTCGGCCAGCCGGCACAGGTCGAAGGCGAAGTGATTTCCAATGAAGTCACGTTCCGCCCGCGTCGCCA
GCTCGTCGTGAAGATCGCTGACGACAGCGGCGAACTCACGCTGCGCTTCCTGAATTTCTACGGCAGCCAGACCAAGCAGA
TGGAAGAGGGCGTGCGCCTGCGCGTGCGCGGCGAGGTCCGCGGCGGCTTCTTCGGGGCCGAGATGGTGCACCCGACGGTG
CGGCCGGTCGCACCGGATGAGCCCTTGCCGGACCGGCTCACGCCCGTCTATCCCGCCACGGCCGGTATTTCGCAAGCCTA
TCTGCGCAAAGCCATCTCCGGCGCGCTAGCGCGTACGCCCTTGCCCGAGACGCTGCCCCCCGCCGTGCTCGAAGGCCCCG
TCGCAAAGCTAAAGCTGCGCCCGCTCGCCGAATCCCTGCGCCTGCTGCATACGCCGCCACCGCAGGAAAGCGAGGCGGCA
CTGGCCGACCGGTCGCATCCGGCCTGGCAGCGCATCAAGTTTGATGAACTGCTCGCTCAGCAGATTTCCTTGCGGCGTGC
CCACGAGGCGCGGCGCGAAAAGAACGCGCCATCGATGCCCCGGCAGGAAGGCGGCCTGCTCACGCGCTTCCTGGCCGCAC
TGCCGTTCCGCCTGACCGGCGCCCAGCAGCGCGTCGTCGAGGAAATCGCGGCCGACATGACCGCGCAGCACCCGATGCAC
CGTCTGCTGCAGGGCGACGTGGGCAGCGGCAAGACCATCGTCGCGGCGCTGGCCGCGTGCCAGGCCATCGACGCCGGCTA
CCAGGCCGCGATCATGGCGCCGACGGAAATCCTGGCCGAGCAGCACTATCGCAAGCTGTCGGCGTGGCTCGAGCCGCTGG
GCGTGCCGGTGGTATGGCTCGCCGGCAGCCTCAAGGCGCGCGAGAAGCGCGAGGCCGTGGCTCGCGTGGAGTCAGGGGAA
GCGCGGCTAGCCATCGGCACGCATGCGCTGATCCAGGACACCGTGCGCTTCGCCAGGCTGGGCTTGTCAGTGGTGGACGA
GCAGCACCGCTTCGGCGTCGCGCAGCGGCTGGCGTTGCGTGGCAAGGCCGGCAGCGCGGAGCCTGCTCAAACTGCCCCGG
ACACCGTCCCCCACCAGCTGATGATGTCGGCCACGCCGATTCCCCGCACGCTGGCCATGACGTATTACGCCGACCTCGAC
GTATCCGTGATCGACGAATTGCCGCCGGGCCGCACGCCGATCGTCACGCGCCTGGTCAATGACGAGCGGCGTGACGAAGT
CATCGACCGTATCCACCATGCCGCCGCAGAAGGGCGCCAGGTCTACTGGGTCTGCCCGCTGATCGAGGAAAGCGAAGCCC
TGCAGCTCCAGACCGCGGTGGAAACCTATGAAACGCTGGTCGCCGCGCTGCCGGACCTGCGCGTCGGCCTGGTCCACGGC
CGCCTGCCGCCGGCCGAGAAGGCGTCCGTGATGGACGATTTCAGCGCCAACCGCCTGCAGGTGCTGGTGGCGACGACGGT
GATCGAAGTCGGCGTAGATGTACCCAATGCCTCGTTGATGGTGATCGAGCATGCCGAGCGTTTCGGCCTCGCGCAGCTCC
ACCAGTTGCGCGGCCGCGTCGGGCGGGGCACCGCGGAGTCCGTCTGCCTGCTGATGTACCAGGCGCCGCTGTCGCCCACG
GCGCGCGAGCGCCTTGCGACCATGCGCGAGACGACCGACGGCTTCGAGATCGCGCGGCGCGACCTCGATATCCGCGGGCC
AGGCGAATTTCTCGGTGCGCGACAGTCCGGTGAAGCGATGCTTCGCTTCGCCGACCTGAACACCGATGCGTGGCTCGTCG
AATATGCTCGGGAAGCCGCACAGGTGATGCTTGCGCAGTTTCCTGAGGCGGTGGAGGCGCATCTGTCGCGCTGGCTCGGC
GGGCGCGAGCACTACCTGAAGGCCTGA

Upstream 100 bases:

>100_bases
GGATAGGTACAATCGGCGAATCCGATATTGTAAGGCTTGGGCGCCAGGCGCCGCCCGGCCCGGTGTGATCCCCCTTATTT
CTCCGCCCGCCCGATTACCG

Downstream 100 bases:

>100_bases
GCTACGGCTCTTTTTGACGACGCAGTGGCCTGTTCGCCGCATTCGCGCGGCGTTCTGACAGATTCGGGAATCGAAGGTAA
AATCTATCGCCTACCGCACA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MPGTATEPTEDKAEAPDSAPSAKAKAAGKAGSKATGKDSKPSSAVARLAKMGLRRSVDLVLHLPMRYEDETTLMPIAEAI
RRSGLGQPAQVEGEVISNEVTFRPRRQLVVKIADDSGELTLRFLNFYGSQTKQMEEGVRLRVRGEVRGGFFGAEMVHPTV
RPVAPDEPLPDRLTPVYPATAGISQAYLRKAISGALARTPLPETLPPAVLEGPVAKLKLRPLAESLRLLHTPPPQESEAA
LADRSHPAWQRIKFDELLAQQISLRRAHEARREKNAPSMPRQEGGLLTRFLAALPFRLTGAQQRVVEEIAADMTAQHPMH
RLLQGDVGSGKTIVAALAACQAIDAGYQAAIMAPTEILAEQHYRKLSAWLEPLGVPVVWLAGSLKAREKREAVARVESGE
ARLAIGTHALIQDTVRFARLGLSVVDEQHRFGVAQRLALRGKAGSAEPAQTAPDTVPHQLMMSATPIPRTLAMTYYADLD
VSVIDELPPGRTPIVTRLVNDERRDEVIDRIHHAAAEGRQVYWVCPLIEESEALQLQTAVETYETLVAALPDLRVGLVHG
RLPPAEKASVMDDFSANRLQVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAESVCLLMYQAPLSPT
ARERLATMRETTDGFEIARRDLDIRGPGEFLGARQSGEAMLRFADLNTDAWLVEYAREAAQVMLAQFPEAVEAHLSRWLG
GREHYLKA

Sequences:

>Translated_728_residues
MPGTATEPTEDKAEAPDSAPSAKAKAAGKAGSKATGKDSKPSSAVARLAKMGLRRSVDLVLHLPMRYEDETTLMPIAEAI
RRSGLGQPAQVEGEVISNEVTFRPRRQLVVKIADDSGELTLRFLNFYGSQTKQMEEGVRLRVRGEVRGGFFGAEMVHPTV
RPVAPDEPLPDRLTPVYPATAGISQAYLRKAISGALARTPLPETLPPAVLEGPVAKLKLRPLAESLRLLHTPPPQESEAA
LADRSHPAWQRIKFDELLAQQISLRRAHEARREKNAPSMPRQEGGLLTRFLAALPFRLTGAQQRVVEEIAADMTAQHPMH
RLLQGDVGSGKTIVAALAACQAIDAGYQAAIMAPTEILAEQHYRKLSAWLEPLGVPVVWLAGSLKAREKREAVARVESGE
ARLAIGTHALIQDTVRFARLGLSVVDEQHRFGVAQRLALRGKAGSAEPAQTAPDTVPHQLMMSATPIPRTLAMTYYADLD
VSVIDELPPGRTPIVTRLVNDERRDEVIDRIHHAAAEGRQVYWVCPLIEESEALQLQTAVETYETLVAALPDLRVGLVHG
RLPPAEKASVMDDFSANRLQVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAESVCLLMYQAPLSPT
ARERLATMRETTDGFEIARRDLDIRGPGEFLGARQSGEAMLRFADLNTDAWLVEYAREAAQVMLAQFPEAVEAHLSRWLG
GREHYLKA
>Mature_727_residues
PGTATEPTEDKAEAPDSAPSAKAKAAGKAGSKATGKDSKPSSAVARLAKMGLRRSVDLVLHLPMRYEDETTLMPIAEAIR
RSGLGQPAQVEGEVISNEVTFRPRRQLVVKIADDSGELTLRFLNFYGSQTKQMEEGVRLRVRGEVRGGFFGAEMVHPTVR
PVAPDEPLPDRLTPVYPATAGISQAYLRKAISGALARTPLPETLPPAVLEGPVAKLKLRPLAESLRLLHTPPPQESEAAL
ADRSHPAWQRIKFDELLAQQISLRRAHEARREKNAPSMPRQEGGLLTRFLAALPFRLTGAQQRVVEEIAADMTAQHPMHR
LLQGDVGSGKTIVAALAACQAIDAGYQAAIMAPTEILAEQHYRKLSAWLEPLGVPVVWLAGSLKAREKREAVARVESGEA
RLAIGTHALIQDTVRFARLGLSVVDEQHRFGVAQRLALRGKAGSAEPAQTAPDTVPHQLMMSATPIPRTLAMTYYADLDV
SVIDELPPGRTPIVTRLVNDERRDEVIDRIHHAAAEGRQVYWVCPLIEESEALQLQTAVETYETLVAALPDLRVGLVHGR
LPPAEKASVMDDFSANRLQVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLRGRVGRGTAESVCLLMYQAPLSPTA
RERLATMRETTDGFEIARRDLDIRGPGEFLGARQSGEAMLRFADLNTDAWLVEYAREAAQVMLAQFPEAVEAHLSRWLGG
REHYLKA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=689, Percent_Identity=50.0725689404935, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1787357, Length=393, Percent_Identity=37.4045801526718, Blast_Score=237, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79550; Mature: 79419

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGTATEPTEDKAEAPDSAPSAKAKAAGKAGSKATGKDSKPSSAVARLAKMGLRRSVDLV
CCCCCCCCCCCHHCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEE
LHLPMRYEDETTLMPIAEAIRRSGLGQPAQVEGEVISNEVTFRPRRQLVVKIADDSGELT
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCEE
LRFLNFYGSQTKQMEEGVRLRVRGEVRGGFFGAEMVHPTVRPVAPDEPLPDRLTPVYPAT
EEEHHHHCCHHHHHHCCCEEEEEEECCCCEECHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AGISQAYLRKAISGALARTPLPETLPPAVLEGPVAKLKLRPLAESLRLLHTPPPQESEAA
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
LADRSHPAWQRIKFDELLAQQISLRRAHEARREKNAPSMPRQEGGLLTRFLAALPFRLTG
HHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCC
AQQRVVEEIAADMTAQHPMHRLLQGDVGSGKTIVAALAACQAIDAGYQAAIMAPTEILAE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHH
QHYRKLSAWLEPLGVPVVWLAGSLKAREKREAVARVESGEARLAIGTHALIQDTVRFARL
HHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
GLSVVDEQHRFGVAQRLALRGKAGSAEPAQTAPDTVPHQLMMSATPIPRTLAMTYYADLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHEEEEEECCC
VSVIDELPPGRTPIVTRLVNDERRDEVIDRIHHAAAEGRQVYWVCPLIEESEALQLQTAV
HHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
ETYETLVAALPDLRVGLVHGRLPPAEKASVMDDFSANRLQVLVATTVIEVGVDVPNASLM
HHHHHHHHHCCCHHEEHEECCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCEE
VIEHAERFGLAQLHQLRGRVGRGTAESVCLLMYQAPLSPTARERLATMRETTDGFEIARR
EEECHHHHHHHHHHHHHHHCCCCCHHHHEEHEEECCCCHHHHHHHHHHHHCCCHHHHHHH
DLDIRGPGEFLGARQSGEAMLRFADLNTDAWLVEYAREAAQVMLAQFPEAVEAHLSRWLG
CCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
GREHYLKA
CCHHHCCC
>Mature Secondary Structure 
PGTATEPTEDKAEAPDSAPSAKAKAAGKAGSKATGKDSKPSSAVARLAKMGLRRSVDLV
CCCCCCCCCCHHCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEE
LHLPMRYEDETTLMPIAEAIRRSGLGQPAQVEGEVISNEVTFRPRRQLVVKIADDSGELT
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCEE
LRFLNFYGSQTKQMEEGVRLRVRGEVRGGFFGAEMVHPTVRPVAPDEPLPDRLTPVYPAT
EEEHHHHCCHHHHHHCCCEEEEEEECCCCEECHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AGISQAYLRKAISGALARTPLPETLPPAVLEGPVAKLKLRPLAESLRLLHTPPPQESEAA
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
LADRSHPAWQRIKFDELLAQQISLRRAHEARREKNAPSMPRQEGGLLTRFLAALPFRLTG
HHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCC
AQQRVVEEIAADMTAQHPMHRLLQGDVGSGKTIVAALAACQAIDAGYQAAIMAPTEILAE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHH
QHYRKLSAWLEPLGVPVVWLAGSLKAREKREAVARVESGEARLAIGTHALIQDTVRFARL
HHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
GLSVVDEQHRFGVAQRLALRGKAGSAEPAQTAPDTVPHQLMMSATPIPRTLAMTYYADLD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHEEEEEECCC
VSVIDELPPGRTPIVTRLVNDERRDEVIDRIHHAAAEGRQVYWVCPLIEESEALQLQTAV
HHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHH
ETYETLVAALPDLRVGLVHGRLPPAEKASVMDDFSANRLQVLVATTVIEVGVDVPNASLM
HHHHHHHHHCCCHHEEHEECCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCEE
VIEHAERFGLAQLHQLRGRVGRGTAESVCLLMYQAPLSPTARERLATMRETTDGFEIARR
EEECHHHHHHHHHHHHHHHCCCCCHHHHEEHEEECCCCHHHHHHHHHHHHCCCHHHHHHH
DLDIRGPGEFLGARQSGEAMLRFADLNTDAWLVEYAREAAQVMLAQFPEAVEAHLSRWLG
CCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
GREHYLKA
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]