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The map label for this gene is iorA [H]

Identifier: 73542347

GI number: 73542347

Start: 2921667

End: 2922125

Strand: Reverse

Name: iorA [H]

Synonym: Reut_A2662

Alternate gene names: 73542347

Gene position: 2922125-2921667 (Counterclockwise)

Preceding gene: 73542349

Following gene: 73542346

Centisome position: 76.77

GC content: 66.45

Gene sequence:

>459_bases
ATGACAACCCTCAATATCAACGGCAAGGCCCAGGAAGTCGACGCGGATCCGTCCACGCCGCTACTGTGGGCCCTGCGCGA
CAACCTTGACCTGACCGGGACCAAATTCGGCTGCGGCATGGCCGCGTGCGGGGCCTGCACGGTCCATATCAACGGCCAGG
CCACGCGCAGCTGCGTGACGCCGATCTCGGCCGCGGCCAGCGCGCGCATTACTACGATCGAAGGCGTGAGCGGCGACAAA
GTCGGGCGCGCTGTACTCGATGCATGGATCAAGCATGACGTGGCCCAGTGCGGCTACTGCCAGAACGGGCAGGTCATGAG
TGCCGTGGGCCTGCTGCGGAACAAGCCGAAACCCACCGACGCCGACATCGACCAGGCCATGGCCGGAAACCTGTGCCGCT
GCGGCACCTACCAACGCATCCGGGCCGCGATCAAAGACGCGGCCCGCGCGCTGGCCTGA

Upstream 100 bases:

>100_bases
AATTGCACTATGCTCATTTGTCCGCGGCGGCAGGCTATTGTCCGCTTCTGTGGCGTGTAAACAAGAACATCGGGCAATGT
ACCCAAGGAGTGTCCTCCCC

Downstream 100 bases:

>100_bases
GCGGAGGTGCCTGACATGCGTATTCGTGGACTCGAAGCACTCGCCGGCGCCAGCAGCGCGCAGGGAAGCAATACTGGCAG
CGCCGGTGATCACGGCGTGG

Product: ferredoxin:(2Fe-2S)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTTLNINGKAQEVDADPSTPLLWALRDNLDLTGTKFGCGMAACGACTVHINGQATRSCVTPISAAASARITTIEGVSGDK
VGRAVLDAWIKHDVAQCGYCQNGQVMSAVGLLRNKPKPTDADIDQAMAGNLCRCGTYQRIRAAIKDAARALA

Sequences:

>Translated_152_residues
MTTLNINGKAQEVDADPSTPLLWALRDNLDLTGTKFGCGMAACGACTVHINGQATRSCVTPISAAASARITTIEGVSGDK
VGRAVLDAWIKHDVAQCGYCQNGQVMSAVGLLRNKPKPTDADIDQAMAGNLCRCGTYQRIRAAIKDAARALA
>Mature_151_residues
TTLNINGKAQEVDADPSTPLLWALRDNLDLTGTKFGCGMAACGACTVHINGQATRSCVTPISAAASARITTIEGVSGDKV
GRAVLDAWIKHDVAQCGYCQNGQVMSAVGLLRNKPKPTDADIDQAMAGNLCRCGTYQRIRAAIKDAARALA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=40.3846153846154, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=38.1578947368421, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=42.8571428571429, Blast_Score=127, Evalue=2e-31,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=37.1621621621622, Blast_Score=88, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=41.6107382550336, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=38.562091503268, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=37.2549019607843, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17737937, Length=159, Percent_Identity=38.3647798742138, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=34.5679012345679, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=33.125, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=33.125, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=33.974358974359, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=32.6923076923077, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15892; Mature: 15761

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLNINGKAQEVDADPSTPLLWALRDNLDLTGTKFGCGMAACGACTVHINGQATRSCVT
CEEECCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHC
PISAAASARITTIEGVSGDKVGRAVLDAWIKHDVAQCGYCQNGQVMSAVGLLRNKPKPTD
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
ADIDQAMAGNLCRCGTYQRIRAAIKDAARALA
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLNINGKAQEVDADPSTPLLWALRDNLDLTGTKFGCGMAACGACTVHINGQATRSCVT
EEECCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHC
PISAAASARITTIEGVSGDKVGRAVLDAWIKHDVAQCGYCQNGQVMSAVGLLRNKPKPTD
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
ADIDQAMAGNLCRCGTYQRIRAAIKDAARALA
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]