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The map label for this gene is ftsK2 [H]

Identifier: 73542285

GI number: 73542285

Start: 2851374

End: 2853698

Strand: Reverse

Name: ftsK2 [H]

Synonym: Reut_A2600

Alternate gene names: 73542285

Gene position: 2853698-2851374 (Counterclockwise)

Preceding gene: 73542289

Following gene: 73542284

Centisome position: 74.97

GC content: 66.06

Gene sequence:

>2325_bases
ATGGCGAGAGCAACCACCACAACCCGGACGGACCCGTCGGCGCTGCCTTCGCGCATCGGCAAACTGCTTGGCGAGGTGCG
CTGGTTCCTGCTGCTCGCCGTCACGCTGGGCTTCCTCTGCGTGCTGGCCAGCTACAGCAAGACCGACCCCGGCTGGTCCC
ACGCCAACCAGGTCGCGGACATCCATAACCTTGGCGGCCGCGTCGGCGCCTGGGTCTCCGACGTACTGTTCTTTATCTTC
GGTTTCTCGGCCTACTGGTGGGCCGTTCTGCTGGTGCGCCGCTGCTGGCGCGGCTGGCGCACGCTGACCGCGGAACTGCC
CGAGCGTGAGGACCACCGCCAGGGCGTGACGGTGAGCTGGATCGGCTTCGTGCTGACGCTGTTTTCCAGCATGGGCCTGG
AAGCCATCCGCATGTACCCGCTGCGGGCCGCGCTGCCGCGTGCGCCGGGCGGCGTGCTCGGCGACCTGATTGGCGGCTGG
ATGCAGACCGCGCTGGGCTTTACCGGTGCCACGCTGCTGCTGCTGCTGATGCTGGCCATCGGCCTGTCGCTGTTCTTCCA
TTTCTCGTGGCTGTCGGTAGCCGAGCATATCGGCGGCTTTGTCGAGACCCTGTTCCTGGGCTTCAAGGCCCGGCGCGAGA
GCAAGCAGGACCGCATCATCGGCAAGGCCGCCAAGGTCGAGCGCACCGAAACCGTGGAAGTGCAGCGCGTGCGTATCGAG
GAAGCGGCGCCCGTGCAGATCGTGCGGCCGCAGGCGGTGCCCAAGCACGAGCGCGTGGAGCGCGAGAAGCAGCAGCCACT
GTTCGCCGATATCCAGGATTCGGACCTACCGCCGCTGGCGCTGCTGGACCCGATCCCGCCGCACCAGGAAACCGTCAGCG
CCGAGACACTGGAATTCACTTCGCGCCTGATCGAGAAGAAGCTCAAGGACTTCGGCGTCGAGGTCAAGGTGGTGGCGGCC
TACCCGGGCCCGGTCATTACGCGCTACGAGATCGAGCCGGCAACCGGCGTGAAGGGCAGCCAGGTGGTGAACCTCGCGCG
CGACCTCGCGCGTTCGCTGTCGCTGGTGTCGATCCGCGTGGTGGAGACCATCCCGGGCAAGAACTACATGGGGCTGGAGT
TGCCGAACCCGAAGCGCCAGACCGTGCGCCTGTCGGAAATCCTCGGCTCGCAGGTCTACAACGAGAGCGCTTCCAGCCTG
ACCATGGCGTTGGGCAAGGACATCGCCGGCAAGCCGATGGTGGCCGACCTTGCCAAGATGCCGCACTGCATGGTGGCCGG
CACGACGGGCTCGGGCAAGTCGGTGGGCATCAATGCGATGATCCTGTCGCTGCTCTACAAGGCCAAGCCCGAGAGCGTGC
GCCTGATCCTGATCGATCCGAAGATGCTCGAAATGAGCGTCTACGAAGGCATTCCGCACCTGTTGTGCCCGGTCGTGACC
GACATGCGCCAGGCGGGCAACGCGCTGAACTGGGCCGTCGGCGAAATGGAGCGGCGCTACAAGCTGATGAGCAAGCTGGG
CGTACGCAACCTGGCCGGCTACAACAAGAAGATCGACGAAGCCGCGGCGAAGGAAGAGAAGATCCCGAACCCGTTCAGCC
TCACGCCGGACGCGCCGGAGCCACTCGACAGGCTGCCGACCATCGTCATCGTCATCGACGAGCTCGCCGACCTGATGATG
GTCGTGGGCAAGAAGGTCGAGGAACTGATCGCGCGTATCGCTCAGAAGGCGCGTGCCGCCGGCCTGCACCTGGTGCTGGC
CACGCAGCGTCCCTCCGTAGACGTGATCACCGGCCTGATCAAGGCCAACGTGCCGACCCGCATTGCGTTCCAGGTCAGCA
GCAAGATCGATTCGCGCACCATCCTTGACCAGCAGGGCGCGGAAGCGCTGCTCGGCATGGGCGACATGCTCTATCTCGCC
CCGGGAACGGGCCTGCCAGTGCGCGTGCACGGCGCCTTTGTCTCCGACGACGAAGTGCACCGCGTGGTGGAAAAGCTCAA
GGAAGGCGGCGAGGCCAACTACATCGAAGGCATCCTCGAAGGCGGCCTGGCTGAAGGCGAGACTGGCACCGATGGCCTTG
GCGGCGGTGCCGGCATTGGCGGCGGCGGTGGCGAAGCGGATCCGCTGTACGACCAGGCAGTGGAAGTCGTGCTGAAGAAC
CGCCGCGCGTCGATCTCGCTGGTGCAGCGCCACCTGCGCATCGGCTACAACCGTGCGGCGCGGCTGCTCGAGGATATGGA
GAAGGCCGGACTGGTGTCGGCCATGTCGGGCAACGGCAACCGGGACATCCTTGCGGCCCCGGGCGCCGCAAGGGAAGATG
ACTGA

Upstream 100 bases:

>100_bases
AGCGCGATTTGCCCACTGTTGCAAATTCCAATGGCGGCGATAGCGCCGCGCCACGTTAAAATGGCCGCCACCATCACCTG
CAAGTGAACCAGATCAAGGC

Downstream 100 bases:

>100_bases
GCGCCGCATCGGTAACATGTGGTTACCCGGTAACCGGCGCAGTGCGGAATCCGGCGCCGGCCGCACGCTCTAACCTGACA
GGTTGCGCCGCCGCCTGATC

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKTDPGWSHANQVADIHNLGGRVGAWVSDVLFFIF
GFSAYWWAVLLVRRCWRGWRTLTAELPEREDHRQGVTVSWIGFVLTLFSSMGLEAIRMYPLRAALPRAPGGVLGDLIGGW
MQTALGFTGATLLLLLMLAIGLSLFFHFSWLSVAEHIGGFVETLFLGFKARRESKQDRIIGKAAKVERTETVEVQRVRIE
EAAPVQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLALLDPIPPHQETVSAETLEFTSRLIEKKLKDFGVEVKVVAA
YPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESASSL
TMALGKDIAGKPMVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKPESVRLILIDPKMLEMSVYEGIPHLLCPVVT
DMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAKEEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLMM
VVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLA
PGTGLPVRVHGAFVSDDEVHRVVEKLKEGGEANYIEGILEGGLAEGETGTDGLGGGAGIGGGGGEADPLYDQAVEVVLKN
RRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILAAPGAAREDD

Sequences:

>Translated_774_residues
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKTDPGWSHANQVADIHNLGGRVGAWVSDVLFFIF
GFSAYWWAVLLVRRCWRGWRTLTAELPEREDHRQGVTVSWIGFVLTLFSSMGLEAIRMYPLRAALPRAPGGVLGDLIGGW
MQTALGFTGATLLLLLMLAIGLSLFFHFSWLSVAEHIGGFVETLFLGFKARRESKQDRIIGKAAKVERTETVEVQRVRIE
EAAPVQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLALLDPIPPHQETVSAETLEFTSRLIEKKLKDFGVEVKVVAA
YPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESASSL
TMALGKDIAGKPMVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKPESVRLILIDPKMLEMSVYEGIPHLLCPVVT
DMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAKEEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLMM
VVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLA
PGTGLPVRVHGAFVSDDEVHRVVEKLKEGGEANYIEGILEGGLAEGETGTDGLGGGAGIGGGGGEADPLYDQAVEVVLKN
RRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILAAPGAAREDD
>Mature_773_residues
ARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKTDPGWSHANQVADIHNLGGRVGAWVSDVLFFIFG
FSAYWWAVLLVRRCWRGWRTLTAELPEREDHRQGVTVSWIGFVLTLFSSMGLEAIRMYPLRAALPRAPGGVLGDLIGGWM
QTALGFTGATLLLLLMLAIGLSLFFHFSWLSVAEHIGGFVETLFLGFKARRESKQDRIIGKAAKVERTETVEVQRVRIEE
AAPVQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLALLDPIPPHQETVSAETLEFTSRLIEKKLKDFGVEVKVVAAY
PGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESASSLT
MALGKDIAGKPMVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKPESVRLILIDPKMLEMSVYEGIPHLLCPVVTD
MRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAKEEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLMMV
VGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAP
GTGLPVRVHGAFVSDDEVHRVVEKLKEGGEANYIEGILEGGLAEGETGTDGLGGGAGIGGGGGEADPLYDQAVEVVLKNR
RASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILAAPGAAREDD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=64.3145161290323, Blast_Score=613, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 84134; Mature: 84003

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKTDPGWSHANQVAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IHNLGGRVGAWVSDVLFFIFGFSAYWWAVLLVRRCWRGWRTLTAELPEREDHRQGVTVSW
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
IGFVLTLFSSMGLEAIRMYPLRAALPRAPGGVLGDLIGGWMQTALGFTGATLLLLLMLAI
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLSLFFHFSWLSVAEHIGGFVETLFLGFKARRESKQDRIIGKAAKVERTETVEVQRVRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEECC
EAAPVQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLALLDPIPPHQETVSAETLEFT
CCCCEEEECCCCCCCHHHHHHHHCCCCEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHHH
SRLIEKKLKDFGVEVKVVAAYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRV
HHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEE
VETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESASSLTMALGKDIAGKPMVADLAKM
EEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHC
PHCMVAGTTGSGKSVGINAMILSLLYKAKPESVRLILIDPKMLEMSVYEGIPHLLCPVVT
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHH
DMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAKEEKIPNPFSLTPDAPE
HHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
PLDRLPTIVIVIDELADLMMVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLI
HHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
KANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSDDEVH
HCCCCCEEEEEEHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEEEECCCHHHH
RVVEKLKEGGEANYIEGILEGGLAEGETGTDGLGGGAGIGGGGGEADPLYDQAVEVVLKN
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILAAPGAAREDD
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
ARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKTDPGWSHANQVAD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IHNLGGRVGAWVSDVLFFIFGFSAYWWAVLLVRRCWRGWRTLTAELPEREDHRQGVTVSW
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
IGFVLTLFSSMGLEAIRMYPLRAALPRAPGGVLGDLIGGWMQTALGFTGATLLLLLMLAI
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLSLFFHFSWLSVAEHIGGFVETLFLGFKARRESKQDRIIGKAAKVERTETVEVQRVRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEECC
EAAPVQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLALLDPIPPHQETVSAETLEFT
CCCCEEEECCCCCCCHHHHHHHHCCCCEECCCCCCCCCCHHCCCCCCCHHHHHHHHHHHH
SRLIEKKLKDFGVEVKVVAAYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRV
HHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEE
VETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESASSLTMALGKDIAGKPMVADLAKM
EEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHC
PHCMVAGTTGSGKSVGINAMILSLLYKAKPESVRLILIDPKMLEMSVYEGIPHLLCPVVT
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHH
DMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAKEEKIPNPFSLTPDAPE
HHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
PLDRLPTIVIVIDELADLMMVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLI
HHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
KANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSDDEVH
HCCCCCEEEEEEHHCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEEEECCCHHHH
RVVEKLKEGGEANYIEGILEGGLAEGETGTDGLGGGAGIGGGGGEADPLYDQAVEVVLKN
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNRDILAAPGAAREDD
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]